Hotels in Santee

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Check prices for these dates

Tonight
Apr 5 - Apr 6
Tomorrow
Apr 6 - Apr 7
Next weekend
Apr 10 - Apr 12
In two weeks
Apr 17 - Apr 19

Where to stay in Santee?

Property amenity
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Comfortable hotel in a tranquil setting, perfect for morning swims and golf outings.
The price is $130
$144 total
includes taxes & fees
Apr 12 - Apr 13
Fairfield Inn & Suites by Marriott Santee
Free breakfast
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,002 reviews)
The price is $125
$139 total
includes taxes & fees
Apr 20 - Apr 21
Hampton Inn Santee-I-95
Free daily full breakfast
Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (497 reviews)
  • cleanliness
    Experience the gateway to Santee's acclaimed golf clubs with complimentary perks.
The price is $54
$66 total
includes taxes & fees
Apr 12 - Apr 13
Quality Inn & Suites Santee I-95
Lobby
Super 8 by Wyndham Santee
Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (449 reviews)
  • cleanliness
    Enjoy a peaceful golf escape at this quiet Santee motel with seasonal pool.
The price is $75
$83 total
includes taxes & fees
Apr 6 - Apr 7
Super 8 by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 star property
Santee
7.8 out of 10, Good, (1,437 reviews)
  • cleanliness
    Relax in peaceful Santee with continental breakfast and helpful staff nearby.
The price is $80
$89 total
includes taxes & fees
Apr 6 - Apr 7
Baymont by Wyndham Santee
In-room safe, iron/ironing board, free WiFi, bed sheets
Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (714 reviews)
The price is $63
$70 total
includes taxes & fees
Apr 12 - Apr 13
Travelodge by Wyndham Santee
Exterior
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,002 reviews)
The price is $119
$132 total
includes taxes & fees
Apr 12 - Apr 13
Best Western Plus Santee Inn
Free daily buffet breakfast
Tru By Hilton Santee
Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (782 reviews)
  • cleanliness
    Experience a comfortable stay near Santee Cooper Country Club with top-rated service.
The price is $115
$128 total
includes taxes & fees
May 4 - May 5
Tru By Hilton Santee
Exterior
Red Roof Inn Santee
Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (648 reviews)
  • cleanliness
    Stay active in Santee with water skiing near this friendly hotel with free perks.
The price is $61
$68 total
includes taxes & fees
Apr 16 - Apr 17
Red Roof Inn Santee
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,002 reviews)
  • cleanliness
    Relax in a serene hotel with a seasonal outdoor pool near Santee attractions.
The price is $112
$124 total
includes taxes & fees
May 4 - May 5
Comfort Inn & Suites Santee
Lobby
Ramada by Wyndham Santee I-95
Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (553 reviews)
  • cleanliness
    Relax at this golf-adjacent hotel with an outdoor pool and 24-hour fitness center.
The price is $79
$88 total
includes taxes & fees
Apr 6 - Apr 7
Ramada by Wyndham Santee I-95
Exterior
Holiday Inn Santee by IHG
Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Golfer's getaway with lakeside views and modern comforts in charming Santee.
The price is $131
$145 total
includes taxes & fees
May 4 - May 5
Holiday Inn Santee by IHG
Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Santee
Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (312 reviews)
  • cleanliness
    Unwind in Santee with easy golf club access and no-cost essentials.
The price is $63
$70 total
includes taxes & fees
Apr 19 - Apr 20
Econo Lodge Santee
Desk, laptop workspace, iron/ironing board, free WiFi
SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1,002 reviews)
  • cleanliness
    Just minutes from I-95, this hotel offers clean, comfortable accommodations.
The price is $99
$110 total
includes taxes & fees
Apr 6 - Apr 7
SureStay Hotel by Best Western Manning
Interior entrance
Hampton Inn Manning
Hampton Inn Manning
2.5 star property
Manning
8.4 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Comfortable South Carolina lodgings near I-95 with 24-hour fitness center.
The price is $125
$139 total
includes taxes & fees
May 3 - May 4
Hampton Inn Manning
Standard Room Double Bed | Desk, free WiFi, bed sheets
Best Inn of Manning
Best Inn of Manning
2.5 star property
Manning
6.8 out of 10, (25 reviews)
The price is $65
$72 total
includes taxes & fees
Apr 28 - Apr 29
Best Inn of Manning
Deluxe Room, 1 King Bed, Non Smoking | Iron/ironing board, free WiFi, bed sheets
Baymont by Wyndham Manning
Baymont by Wyndham Manning
2.5 star property
Manning
6.8 out of 10, (1,001 reviews)
  • cleanliness
    Manning hotel with free breakfast and parking for easy SC travel.
The price is $84
$93 total
includes taxes & fees
Apr 19 - Apr 20
Baymont by Wyndham Manning
Free buffet breakfast
Quality Inn Manning I-95
Quality Inn Manning I-95
2.5 star property
Manning
6.8 out of 10, (511 reviews)
  • cleanliness
    Rest peacefully at this Manning hotel just off I-95 with free parking and breakfast.
The price is $84
$93 total
includes taxes & fees
Apr 26 - Apr 27
Quality Inn Manning I-95
Reception
Super 8 by Wyndham Manning
Super 8 by Wyndham Manning
2.0 star property
Manning
6.4 out of 10, (399 reviews)
  • cleanliness
    Located in Manning with helpful staff and convenient freebies like WiFi and breakfast.
The price is $61
$68 total
includes taxes & fees
Apr 19 - Apr 20
Super 8 by Wyndham Manning
1 bedroom
Starlight Stays
Starlight Stays
2.5 star property
Manning
7.6 out of 10, Good, (10 reviews)
  • cleanliness
    Tranquil Manning retreat near Wyboo Golf Club with complimentary parking.
The price is $66
$73 total
includes taxes & fees
Apr 6 - Apr 7
Starlight Stays
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Get last-minute hotel deals in Santee and save more

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Showing deals for:Apr 5 - Apr 6
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
7.8 out of 10, Good, (1,437 reviews)
The price is $80
per night
$89 total
includes taxes & fees
Baymont by Wyndham Santee
Showing deals for:Apr 6 - Apr 7
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
7.8 out of 10, Good, (1,437 reviews)
The price is $80
per night
$89 total
includes taxes & fees
Baymont by Wyndham Santee
Showing deals for:Apr 10 - Apr 12
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
7.8 out of 10, Good, (1,437 reviews)
The price is $100
per night
$222 total
includes taxes & fees
MOD
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Baymont by Wyndham Santee

Check out pet-friendly hotels in Santee

Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
7.8 out of 10, Good, (1437)
The price is $80
$89 total
includes taxes & fees
Apr 6 - Apr 7
Baymont by Wyndham Santee
View all properties

You may also like hotels with pools in Santee

Free daily buffet breakfast
Tru By Hilton Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (782)
The price is $115
$128 total
includes taxes & fees
May 4 - May 5
Tru By Hilton Santee
View all properties

You can also stay at family-friendly hotels in Santee

Exterior
Best Western Plus Santee Inn

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1002)
The price is $119
$132 total
includes taxes & fees
Apr 12 - Apr 13
Best Western Plus Santee Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit Santee?

Our prices for hotels in Santee are cheapest in January
Price trends for hotels in Santee
Pricing is based on two traveler single night rates
View properties in April
Currently viewing crowd sizes and weather for April.
Typical weather for Santee
April
High 24°C / low 13°C. Sunny most days.
View properties in April
24°
weather_sun
April, no crowd data, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
28°
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May, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
31°
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June, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
33°
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July, no crowd data, average high temperature 33 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
32°
weather_sun
August, no crowd data, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
29°
weather_sun
September, no crowd data, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
24°
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October, no crowd data, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
19°
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November, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
15°
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December, no crowd data, average high temperature 15 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
7°
13°
weather_sun
January, no crowd data, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
4°
16°
weather_sun
February, no crowd data, average high temperature 16 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
6°
19°
weather_sun
March, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
Monthly weather averages (˚C)

Top landmarks in Santee

Santee State Park

4.0/5 (219 reviews)
Rent a pier cabin at Santee State Park for unmatched views of South Carolina's largest lake. Explore 10 miles of trails winding through cypress swamps where alligators and diverse bird species await.
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Santee Cooper Country Club

3.9/5 (94 reviews)
Wind through majestic pines on George Cobb's scenic 18-hole course overlooking Lake Marion. The signature closing hole offers a panoramic view that makes the challenging doglegs and strategic bunkering worth every swing.
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Learn more about Santee

Tee off at championship golf courses or cast a line in Lake Marion's fish-rich waters where locals claim the bass practically jump into your boat. The Santee National Wildlife Refuge offers hiking trails where alligators sun themselves with reptilian nonchalance. Interstate 95 crosses the lake on a causeway that provides views worth pulling over for (safely, of course). Santee State Park delivers lakeside tranquility that makes visitors forget their phones exist. This resort town punches well above its weight with dining options that range from fresh-caught catfish to surprisingly sophisticated fare. The recent addition of the Santee Cooper Regional Water System has locals buzzing about growth while still cherishing their small-town atmosphere.

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Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Check out reviews of Santee hotels guests love

Baymont by Wyndham Santee

Baymont by Wyndham Santee

4/10 Poor
"TV not working. Staff refused to help. Shampoo and conditioner bottles were empty. Staff offered "sorry"."
Nancy 1-night trip
Posted 9 hours ago
Baymont by Wyndham Santee

Frequently asked questions

What accommodations do travelers like in Santee?
Hampton Inn Santee-I-95, Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee are all accommodations that are popular with guests.
Can I book refundable accommodations in Santee?
If you want the flexibility to change your plans to Santee, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where should I stay in Santee if I'm looking for a reasonably priced accommodation?
A few inexpensive options worth considering are Baymont by Wyndham Santee, Tru By Hilton Santee and Best Western Plus Santee Inn.
Where can I stay in Santee if I want a vacation rental instead of a hotel?
Browse 8 vacation homes on our site. You also might want to book one of 98 condos for your trip.
What will the weather in Santee be like during my vacation?
July and August are typically the warmest months in Santee when the average temp is 79°F. January and February are the coldest months when the average temperature is 52°F. August and July are the months with the most rain.
Why should I book my Santee hotel with Hotels.com?
There are lots of reasons to book your Santee trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.