Hotels in Saint Matthews

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Top 5 hotels in Saint Matthews at a glance

1. Red Roof Inn Orangeburg — 2-star hotel in Orangeburg. Guest rating: 5.6/10.
2. Fairfield Inn by Marriott Orangeburg — 3-star hotel in Orangeburg. Guest rating: 8.4/10 — Very Good.
3. Spark by Hilton Orangeburg — 2.5-star hotel in Orangeburg. Guest rating: 7.8/10 — Good.
4. Tru by Hilton Orangeburg — 2.5-star hotel in Orangeburg. Guest rating: 9.2/10 — Wonderful.
5. Quality Inn & Suites Orangeburg — 2.5-star hotel in Orangeburg. Guest rating: 6.2/10.

Where to stay in Saint Matthews?

A hotel reception area with a counter, coffee machines, and a refrigerator.

A Red Roof Inn with two red leather armchairs and a small wooden table in front of a stone-patterned wall.

A two-story building with a grey facade, large windows, and a covered entrance area.

A Red Roof Inn sign, a Waffle House sign, and a BP gas station.

1. Red Roof Inn Orangeburg

Orangeburg

$58

$65 total

includes taxes & fees

Aug 30 - Aug 31

A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

A modern bar area with a stone fireplace, a flat-screen TV, and a coffee station.

A reception area with a wooden reception desk, a welcome mat, a vending machine, and a clock on the wall.

A corner market with a refrigerator stocked with beverages and snacks.

2. Fairfield Inn by Marriott Orangeburg

Orangeburg

$101

$112 total

includes taxes & fees

Aug 24 - Aug 25

A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

A lobby with a reception desk, a staircase, and seating area with orange chairs.

A modern kitchen with a wooden table and bench, blue cabinets, and a yellow pendant light fixture.

A modern indoor swimming pool with clear glass walls, sunlit lounge areas, and a view of greenery outside.

3. Spark by Hilton Orangeburg

Orangeburg

$98

$108 total

includes taxes & fees

Aug 26 - Aug 27

A self-service kiosk with a beverage cooler, microwave, and various food items.

A modern interior with a dining area, seating arrangements, and a reception desk.

A pool table in a room with a colorful mural, chairs, and a sofa.

A breakfast counter with a sign reading 'TOP IT BREAKFAST,' a coffee machine, a yogurt dispenser, and various food items.

4. Tru by Hilton Orangeburg

Orangeburg

$114

$127 total

includes taxes & fees

Sep 6 - Sep 7

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A spacious lobby with a central round table and chairs, a bar area, and a staircase leading to an upper level.

A spacious living area with a sofa, two patterned armchairs, a wooden coffee table, and a ceiling fan. A flat-screen TV is mounted on the wall, and a kitchen area is visible in the background.

A pool area with lounge chairs and a building in the background.

5. Quality Inn & Suites Orangeburg

Orangeburg

$60

$66 total

includes taxes & fees

Sep 13 - Sep 14

A breakfast bar with pastries, fruits, and a vase with flowers.

A reception area with a dark-colored reception desk, a clock on the wall, and a doormat with "Travelodge" written on it.

A Travelodge motel with a parking lot and a signboard.

A hotel bathroom with a sink, mirror, towel rack, and a door leading to the bedroom.

6. Travelodge by Wyndham Orangeburg

Orangeburg

$79

$88 total

includes taxes & fees

Aug 24 - Aug 25

A spacious lobby with a sofa, chairs, a coffee table, and a staircase with a green leaf-patterned wall.

A hotel room with a bed, bedside tables, a nightstand, a lamp, a wall-mounted phone, a painting, a window with curtains, and an air conditioning unit.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a modern design.

A reception area with a staircase, reception desk, and seating area with blue sofas.

7. Sleep Inn Orangeburg

Orangeburg

$89

$99 total

includes taxes & fees

Aug 30 - Aug 31

A hotel room with a large bed, a desk, a chair, a nightstand, and a wall-mounted lamp.

A lobby with a reception desk, a sofa, a small round table, and an American flag.

A modern hotel lobby with a reception desk, seating area, and a coffee bar.

8. Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

$114

$127 total

includes taxes & fees

Sep 6 - Sep 7

A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

A hotel room with two beds, a seating area, and a large abstract painting on the wall.

A modern hotel room with a grey sofa, a flat-screen TV, a desk with a lamp, and abstract wall art.

An outdoor patio area with a fire pit, seating, and tables.

9. SpringHill Suites by Marriott Orangeburg

Orangeburg

$109

$121 total

includes taxes & fees

Aug 30 - Aug 31

A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

A hotel room with a large bed, a desk with a flat-screen TV, a chair, a desk lamp, and a window with curtains.

A modern dining area with tables and chairs, large windows with sheer curtains, and pendant lighting.

A snack shop with a sign reading "Hampton Suite Shop" and a variety of snacks and drinks on display.

10. Hampton Inn & Suites Orangeburg

Orangeburg

$130

$145 total

includes taxes & fees

Sep 6 - Sep 7

A restaurant with round tables and chairs, a counter with a display case, and large windows.

A hotel room with two beds, a desk, and a mirror.

A kitchen with wooden cabinets, a stainless steel range hood, and a black refrigerator.

A reception desk with a laptop, a patterned sofa, and a doormat with "SOUTHERN" visible.

11. Southern Lodge 601

Orangeburg

$77

$85 total

includes taxes & fees

Aug 24 - Aug 25

A hotel room with two beds, a desk, and a chair. There are wall-mounted lamps and a large window with curtains.

A restaurant with multiple tables and chairs, a wooden counter, and a painting on the wall.

A reception area with a wooden reception desk, a wall-mounted clock, and a welcome mat.

A swimming pool with a 4ft depth marker, lounge chairs, and a covered seating area.

12. Comfort Inn & Suites Orangeburg

Orangeburg

$105

$117 total

includes taxes & fees

Sep 14 - Sep 15

A modern kitchen with a long counter, equipped with coffee makers, a kettle, and a microwave.

A hotel room with a beige armchair, a black ottoman, a standing lamp, and an air conditioning unit.

A multi-story hotel with a covered entrance, balconies, and a parking area.

A living room with a brown leather sofa, a matching armchair, a coffee table, and a striped rug.

13. Super 8 by Wyndham, Orangeburg

Orangeburg

$58

$64 total

includes taxes & fees

Sep 1 - Sep 2

A hotel room with a bed, a desk, a chair, and a hanging coat rack.

A reception area with a stone wall, wooden reception desk, and a seating area with a TV and plants.

A spacious living area with a wooden floor, a ceiling fan, a flat-screen TV, and a large window with sheer curtains.

A modern kitchen with a granite countertop, a built-in microwave, a sink, and a mirror above the counter.

14. Suburban Studios Orangeburg

Orangeburg

$64

$71 total

includes taxes & fees

Sep 21 - Sep 22

A hotel room with a bed, a desk, a chair, a sofa, and a table.

A gym with cardio equipment, dumbbells, and a TV on a shelf.

A Baymont Inn & Suites reception desk with a sign indicating Orangeburg, South Carolina.

A hotel with a swimming pool, outdoor seating, and a flagpole with an American flag.

15. Baymont by Wyndham Orangeburg North

Orangeburg

$55

$61 total

includes taxes & fees

Aug 30 - Aug 31

A hotel room with a sofa, a bed with a red blanket, two bedside lamps, a small table, and a TV.

A motel with a row of single-story rooms, a covered front porch, and a parking lot.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A parking lot with multiple cars and a yellow truck.

16. Orangeburg Inn & Suites

Orangeburg

$63

$71 total

includes taxes & fees

Aug 24 - Aug 25

A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

A hotel corridor with blue doors, a covered walkway, and a parking lot in the background.

A lobby with two leather armchairs, a marble-topped table, and a patterned carpet.

A spacious dining area with multiple tables and chairs, large windows, and a patterned carpet.

17. Baymont by Wyndham Santee

Santee

$80

$89 total

includes taxes & fees

Aug 24 - Aug 25

A hotel entrance with a sign reading "Best Western PLISS."

A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.

A hotel room with two large beds, a wooden headboard, bedside tables with lamps, a wardrobe, and a view of the outdoors through a window.

A spacious living room with a large window, a ceiling fan, and a vibrant red accent wall.

18. Best Western Plus Santee Inn

Santee

$111

$123 total

includes taxes & fees

Aug 30 - Aug 31

A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

A hotel room with two beds, a desk, and a large window with a view.

A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.

A modern hotel lobby with a central reception desk, a children's play area, and a restaurant named "Top It Break."

19. Tru By Hilton Santee

Santee

$98

$108 total

includes taxes & fees

Aug 30 - Aug 31

A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

A gym with treadmills, weight machines, and a wall of dumbbells.

A Hampton Inn hotel at night with a well-lit facade and a parking lot in the foreground.

A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.

20. Hampton Inn Santee-I-95

Santee

$123

$137 total

includes taxes & fees

Sep 7 - Sep 8

View all properties

Go beyond your typical stay in Saint Matthews

Pet friendly

Pool

Family friendly

Learn more about Saint Matthews

The region around Saint Matthews is home to attractions such as Congaree National Park and Edisto Memorial Gardens.

See all hotels in Saint Matthews

A swamp with tall trees and water reflecting the greenery.

Check out reviews of Saint Matthews hotels guests love

Quality Inn Columbia Airport

10/10 Excellent

"We were very pleased after reading so many bad reviews. The hotel was clean, wonderful staff, great breakfast that had cereal, waffles, eggs, sausage gravy, fruit, pastries and breads. Our room had a nice smell when we opened the door and the air was on so nice and cool. Now if you are fussy well then you should not be shopping in this price point. Chipped paint, cracks here or there or a little dust in high corners do not bother us. All we care about is what we and other people will be touching us cleanand this certainly was. In fact the hotel exceeded our expectations and will stay again."

Baymont by Wyndham Santee

8/10 Good

"Clean. Comfortable bed. Breakfast was lacking."

Country Inn & Suites by Radisson, Columbia Airport, SC

10/10 Excellent

"Clean and quiet"

Holiday Inn Columbia - Downtown by IHG

10/10 Excellent

"Clean room, helpful and friendly staff."

Hyatt Place Columbia/Downtown/The Vista

10/10 Excellent

"Everyone was so friendly"

Sheraton Columbia Downtown Hotel

10/10 Excellent

"Clean room"

Frequently asked questions

What hotels do travelers like in Saint Matthews?

Guests like Tru by Hilton Orangeburg.

Can I book a refundable hotel in Saint Matthews?

If you want the flexibility to change your travel plans to Saint Matthews, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Saint Matthews be like during my trip?

July and August are typically the warmest months in Saint Matthews when the average temp is 79°F. January and February are the coldest months when the average temperature is 51°F. August and July are the months with the most rain.

Why should I book my Saint Matthews accommodation with Hotels.com?

There are lots of reasons to book your Saint Matthews trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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