Hotels in Santee

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Jan 19 - Jan 20
Tomorrow
Jan 20 - Jan 21
This weekend
Jan 23 - Jan 25
Next weekend
Jan 30 - Feb 1

Where to stay in Santee?

Free daily buffet breakfast
Tru By Hilton Santee
Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (688 reviews)
  • cleanliness
    Experience a comfortable stay near Santee Cooper Country Club with top-rated service.
The price is $107
$119 total
includes taxes & fees
Jan 26 - Jan 27
Tru By Hilton Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,427 reviews)
  • cleanliness
    Relax in peaceful Santee with continental breakfast and helpful staff nearby.
The price is $75
$83 total
includes taxes & fees
Jan 20 - Jan 21
Baymont by Wyndham Santee
Property amenity
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 star property
Santee
9.8 out of 10, Exceptional, (1,005 reviews)
  • cleanliness
    Comfortable hotel in a tranquil setting, perfect for morning swims and golf outings.
The price is $121
$134 total
includes taxes & fees
Jan 25 - Jan 26
Fairfield Inn & Suites by Marriott Santee
Exterior
Holiday Inn Santee by IHG
Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (989 reviews)
  • cleanliness
    Golfer's getaway with lakeside views and modern comforts in charming Santee.
The price is $112
$124 total
includes taxes & fees
Feb 8 - Feb 9
Holiday Inn Santee by IHG
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,004 reviews)
  • cleanliness
    Relax in a serene hotel with a seasonal outdoor pool near Santee attractions.
The price is $103
$114 total
includes taxes & fees
Jan 25 - Jan 26
Comfort Inn & Suites Santee
In-room safe, iron/ironing board, free WiFi, bed sheets
Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2.0 star property
Santee
7.0 out of 10, Good, (688 reviews)
The price is $62
$69 total
includes taxes & fees
Jan 20 - Jan 21
Travelodge by Wyndham Santee
Free breakfast
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,005 reviews)
The price is $124
$137 total
includes taxes & fees
Jan 26 - Jan 27
Hampton Inn Santee-I-95
Exterior
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,002 reviews)
The price is $119
$132 total
includes taxes & fees
Jan 25 - Jan 26
Best Western Plus Santee Inn
Free daily full breakfast
Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (466 reviews)
  • cleanliness
    Experience the gateway to Santee's acclaimed golf clubs with complimentary perks.
The price is $54
$66 total
includes taxes & fees
Jan 25 - Jan 26
Quality Inn & Suites Santee I-95
Lobby
Ramada by Wyndham Santee I-95
Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (548 reviews)
  • cleanliness
    Relax at this golf-adjacent hotel with an outdoor pool and 24-hour fitness center.
The price is $61
$67 total
includes taxes & fees
Jan 25 - Jan 26
Ramada by Wyndham Santee I-95
Exterior
Red Roof Inn Santee
Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (642 reviews)
  • cleanliness
    Stay active in Santee with water skiing near this friendly hotel with free perks.
The price is $70
$78 total
includes taxes & fees
Jan 22 - Jan 23
Red Roof Inn Santee
Lobby
Super 8 by Wyndham Santee
Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (441 reviews)
  • cleanliness
    Enjoy a peaceful golf escape at this quiet Santee motel with seasonal pool.
The price is $70
$78 total
includes taxes & fees
Jan 20 - Jan 21
Super 8 by Wyndham Santee
Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Santee
Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (310 reviews)
  • cleanliness
    Unwind in Santee with easy golf club access and no-cost essentials.
The price is $62
$68 total
includes taxes & fees
Feb 15 - Feb 16
Econo Lodge Santee
Panoramic Tent | Lake view
Bells Marina & Resort
Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (86 reviews)
  • cleanliness
    Tucked away on the water, this Eutawville resort offers marina access and golf.
The price is $94
$105 total
includes taxes & fees
Jan 20 - Jan 21
Bells Marina & Resort
Front of property
Peach Tree Inn
Peach Tree Inn
2.5 star property
St. George
7.4 out of 10, Good, (154 reviews)
The price is $68
$73 total
includes taxes & fees
Jan 20 - Jan 21
Peach Tree Inn
1 bedroom
Starlight Stays
Starlight Stays
2.5 star property
Manning
7.0 out of 10, Good, (7 reviews)
  • cleanliness
    Tranquil Manning retreat near Wyboo Golf Club with complimentary parking.
The price is $67
$75 total
includes taxes & fees
Feb 11 - Feb 12
Starlight Stays
Lobby
Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott Orangeburg
2.5 star property
Orangeburg
8.4 out of 10, Very Good, (711 reviews)
  • cleanliness
    Swim into comfort at this Orangeburg hotel with fitness options and seasonal pool.
The price is $84
$93 total
includes taxes & fees
Jan 25 - Jan 26
Fairfield Inn by Marriott Orangeburg
Interior entrance
Hampton Inn Manning
Hampton Inn Manning
2.5 star property
Manning
8.4 out of 10, Very Good, (1,001 reviews)
  • cleanliness
    Comfortable South Carolina lodgings near I-95 with 24-hour fitness center.
The price is $119
$132 total
includes taxes & fees
Jan 26 - Jan 27
Hampton Inn Manning
Seasonal outdoor pool
Spark by Hilton Orangeburg
Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,001 reviews)
  • cleanliness
    Central stay in Orangeburg with seasonal pool and complimentary breakfast.
The price is $87
$97 total
includes taxes & fees
Feb 1 - Feb 2
Spark by Hilton Orangeburg
Free daily buffet breakfast
Tru by Hilton Orangeburg
Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,005 reviews)
The price is $115
$127 total
includes taxes & fees
Feb 5 - Feb 6
Tru by Hilton Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Get last-minute hotel deals in Santee and save more

Sign in to unlock great savings.
Showing deals for:Jan 19 - Jan 20
Free daily buffet breakfast
Tru By Hilton Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (688 reviews)
The price is $125
per night
$139 total
includes taxes & fees
Tru By Hilton Santee
Showing deals for:Jan 20 - Jan 21
Free daily buffet breakfast
Tru By Hilton Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (688 reviews)
The price is $127
per night
$141 total
includes taxes & fees
Tru By Hilton Santee
Showing deals for:Jan 30 - Feb 1
Free daily buffet breakfast
Tru By Hilton Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (688 reviews)
The price is $140
per night
$312 total
includes taxes & fees
Tru By Hilton Santee

Check out pet-friendly hotels in Santee

Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
2.5 star property
Santee
9.8 out of 10, Exceptional, (1005)
The price is $121
$134 total
includes taxes & fees
Jan 25 - Jan 26
Fairfield Inn & Suites by Marriott Santee
View all properties

You may also like hotels with pools in Santee

Free daily buffet breakfast
Tru By Hilton Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (688)
The price is $107
$119 total
includes taxes & fees
Jan 26 - Jan 27
Tru By Hilton Santee
View all properties

You can also stay at family-friendly hotels in Santee

Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
2.5 star property
Santee
9.8 out of 10, Exceptional, (1005)
The price is $121
$134 total
includes taxes & fees
Jan 25 - Jan 26
Fairfield Inn & Suites by Marriott Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit Santee?

Our prices for hotels in Santee are cheapest in January
Price trends for hotels in Santee
Pricing is based on two traveler single night rates
View properties in January
Currently viewing crowd sizes and weather for January.
Typical weather for Santee
January
High 13°C / low 4°C. Sunny most days.
View properties in January
13°
weather_sun
January, no crowd data, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
4°
16°
weather_sun
February, no crowd data, average high temperature 16 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
6°
19°
weather_sun
March, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
24°
weather_sun
April, no crowd data, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
28°
weather_sun
May, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
31°
weather_sun
June, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
33°
weather_sun
July, no crowd data, average high temperature 33 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
32°
weather_sun
August, no crowd data, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
29°
weather_sun
September, no crowd data, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
24°
weather_sun
October, no crowd data, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
19°
weather_sun
November, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
15°
weather_sun
December, no crowd data, average high temperature 15 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
7°
Monthly weather averages (˚C)

Top landmarks in Santee

Santee State Park

4.0/5 (112 reviews)
Santee State Park is 2.7 mi (4.4 km) from central Santee, why not stop by during your stay.
See properties

Santee Cooper Country Club

3.9/5 (47 reviews)
You might want to play some rounds at Santee Cooper Country Club, located 0.6 mi (1 km) from central Santee. If Santee Cooper Country Club doesn't quite scratch your golfing itch, Santee National Golf Club is also nearby.
See properties

Learn more about Santee

Tee off at championship golf courses or cast a line in Lake Marion's fish-rich waters where locals claim the bass practically jump into your boat. The Santee National Wildlife Refuge offers hiking trails where alligators sun themselves with reptilian nonchalance. Interstate 95 crosses the lake on a causeway that provides views worth pulling over for (safely, of course). Santee State Park delivers lakeside tranquility that makes visitors forget their phones exist. This resort town punches well above its weight with dining options that range from fresh-caught catfish to surprisingly sophisticated fare. The recent addition of the Santee Cooper Regional Water System has locals buzzing about growth while still cherishing their small-town atmosphere.

See all hotels in Santee
Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Check out reviews of Santee hotels guests love

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

10/10 Excellent
"The afternoon-night clerk was wonderful, friendly, professional and helpful. We received cookies and water at check-in, a nice touch. The room was clean and comfortable and breakfast good. "
Karmela 1-night trip
Posted 18 hours ago
Fairfield Inn & Suites by Marriott Santee

Frequently asked questions

What accommodations do travelers like in Santee?
Hampton Inn Santee-I-95, Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee are all accommodations that are popular with guests.
Can I book refundable accommodations in Santee?
If you want the flexibility to change your plans to Santee, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where should I stay in Santee if I'm looking for a reasonably priced accommodation?
A few inexpensive options worth considering are Tru By Hilton Santee, Baymont by Wyndham Santee and Hampton Inn Santee-I-95.
Where can I stay in Santee if I want a vacation rental instead of a hotel?
Browse 7 vacation homes on our site. You also might want to book one of 95 condos for your trip.
What will the weather in Santee be like during my vacation?
July and August are typically the warmest months in Santee when the average temp is 79°F. January and February are the coldest months when the average temperature is 52°F. August and July are the months with the most rain.
Why should I book my Santee hotel with Hotels.com?
There are lots of reasons to book your Santee trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.