Hotels in South Main
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Top 5 hotels in South Main at a glance
- Wyndham Houston near NRG Park/Medical Center — 3.5-star hotel in South Main. Guest rating: 7.2/10 — Good.
- Comfort Suites Houston near Medical Center- NRG Stadium — 2.5-star hotel in South Main. Guest rating: 8.8/10 — Excellent.
- Wingate Houston near NRG Park/Medical Center — 3-star hotel in South Main. Guest rating: 6.6/10.
- Quality Inn & Suites NRG Park - Medical Center — 2.5-star hotel in South Main. Guest rating: 6.6/10.
- Candlewood Suites Houston Medical Center by IHG — 2.5-star hotel in South Main. Guest rating: 7.4/10 — Good.
Where to stay in South Main?
Wyndham Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical CenterSouth Main
7.2 out of 10, Good, (1,381 reviews)
"Bar was nice parking had plenty and rooms super clean "
Luis
The price is $77
$90 total
includes taxes & fees
Sep 2 - Sep 3
Comfort Suites Houston near Medical Center- NRG Stadium
Comfort Suites Houston near Medical Center- NRG StadiumSouth Main
8.8 out of 10, Excellent, (1,001 reviews)
"The hotel rooms were very clean. The staff were very nice. There were security cameras everywhere, even in the elevators, but the stay wasn’t bad at all."
LaKeisha
The price is $97
$114 total
includes taxes & fees
Sep 1 - Sep 2
Wingate Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical CenterSouth Main
6.6 out of 10, (1,003 reviews)
"My overall stay was good and property was well maintained and cleaned and staff was super helpful"
Terry
The price is $74
$87 total
includes taxes & fees
Aug 5 - Aug 6
Quality Inn & Suites NRG Park - Medical Center
Quality Inn & Suites NRG Park - Medical CenterSouth Main
6.6 out of 10, (1,012 reviews)
"The room was ok don't expect a 5 ⭐️ room, staff was great especially the maintenance man he helped us out a lot when the ac and tv wasn't working right he transferred us too another room with no questions asked. The breakfast was great 😋 and the parking was excellent."
HERBERT
The price is $59
$69 total
includes taxes & fees
Sep 1 - Sep 2
Candlewood Suites Houston Medical Center by IHG
Candlewood Suites Houston Medical Center by IHGSouth Main
7.4 out of 10, Good, (889 reviews)
"Everything was clean and the staff was helpful. Close to lots of restaurants and had a shuttle to the stadium."
Barbara
The price is $74
$87 total
includes taxes & fees
Aug 27 - Aug 28
Hyatt Place Houston Medical Center
Hyatt Place Houston Medical CenterTexas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (2,609 reviews)
"We thoroughly enjoyed our stay! The room was perfect. The breakfast was amazing. The staff was great. Super nice hotel!!"
Marcus
The price is $127
$149 total
includes taxes & fees
Aug 10 - Aug 11
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG1.4 km from South Main
9.4 out of 10, Exceptional, (1,010 reviews)
"Clean! Friendly staff! Easy check in/out"
LINDSEY
The price is $118
$139 total
includes taxes & fees
Aug 9 - Aug 10
Blossom Hotel Houston, Curio Collection by Hilton
Blossom Hotel Houston, Curio Collection by HiltonTexas Medical Center, 3.5 km from South Main
9.0 out of 10, Wonderful, (3,855 reviews)
"Very nice place to stay center of medical center close proximity to great places to visit"
Samantha
The price is $146
$170 total
includes taxes & fees
Sep 3 - Sep 4
Hyatt House Houston Medical Center
Hyatt House Houston Medical CenterTexas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (1,263 reviews)
"It was very comfortable stay !"
estella
The price is $126
$149 total
includes taxes & fees
Aug 15 - Aug 16
The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictTexas Medical Center, 4.4 km from South Main
9.2 out of 10, Wonderful, (1,167 reviews)
"Rooms clean and enjoyed the bar downstairs."
Sheila
The price is $152
$189 total
includes taxes & fees
Aug 8 - Aug 9
Hilton Garden Inn Houston Medical Center, TX
Hilton Garden Inn Houston Medical Center, TXTexas Medical Center, 4.7 km from South Main
9.2 out of 10, Wonderful, (1,004 reviews)
"Breakfast buffet was amazing!"
Darren
The price is $114
$133 total
includes taxes & fees
Aug 16 - Aug 17
Best Western Plus Pearland/Houston Medical Center Hotel
Best Western Plus Pearland/Houston Medical Center HotelSoutheast Houston, 10.2 km from South Main
9.4 out of 10, Exceptional, (379 reviews)
"The staff is always friendly and helpful."
Sharon
The price is $80
$94 total
includes taxes & fees
Aug 6 - Aug 7
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterTexas Medical Center, 4.4 km from South Main
8.4 out of 10, Very Good, (2,080 reviews)
"Fantastic staff. Good food and nice bar."
aseem
The price is $81
$95 total
includes taxes & fees
Aug 16 - Aug 17
Home2 Suites by Hilton at the Galleria
Home2 Suites by Hilton at the GalleriaGreater Uptown, 8 km from South Main
9.0 out of 10, Wonderful, (1,011 reviews)
"It's was outstanding room 609 nice, very very clean breakfast was great and the staff was nice and sweet and helpful Love all of it."
Kevin
The price is $106
$124 total
includes taxes & fees
Aug 10 - Aug 11
Hotel Ylem
Hotel Ylem2.3 km from South Main
8.4 out of 10, Very Good, (1,544 reviews)
"Great Comfy bed, Amazing Hot Shower and Room was super cold and relaxing, we will definitely be using this hotel for future stays !!!"
Monica
The price is $78
$96 total
includes taxes & fees
Aug 11 - Aug 12
DoubleTree by Hilton Hotel Houston - Greenway Plaza
DoubleTree by Hilton Hotel Houston - Greenway PlazaGreenway Plaza-Upper Kirby, 6.6 km from South Main
8.4 out of 10, Very Good, (1,783 reviews)
"really nice staff, super helpful, not one complaint to give."
Nicole
The price is $81
$95 total
includes taxes & fees
Aug 15 - Aug 16
Drury Inn & Suites Houston Near the Galleria
Drury Inn & Suites Houston Near the GalleriaThe Galleria, 9.4 km from South Main
9.4 out of 10, Exceptional, (1,499 reviews)
"The amenities are great, nice clean hotel and the team couldn’t be more proficient and kind. They made my stay a very nice and comfortable one."
Karen
The price is $90
$105 total
includes taxes & fees
Aug 9 - Aug 10
Best Western Plus Downtown Inn & Suites
Best Western Plus Downtown Inn & Suites10.2 km from South Main
9.2 out of 10, Wonderful, (1,115 reviews)
"Good stay
Clean room
Helpful staff"
Karen
The price is $118
$138 total
includes taxes & fees
Aug 10 - Aug 11
Hyatt Place Houston/Galleria
Hyatt Place Houston/Galleria8.7 km from South Main
8.8 out of 10, Excellent, (1,564 reviews)
"location was good and stay"
desiree
The price is $111
$131 total
includes taxes & fees
Aug 5 - Aug 6
Studio 6 Houston, TX – Pearland/Medical Center
Studio 6 Houston, TX – Pearland/Medical CenterSoutheast Houston, 12.9 km from South Main
9.2 out of 10, Wonderful, (177 reviews)
"Very nice, and clean. Comfortable and quiet"
Pamela
The price is $60
$70 total
includes taxes & fees
Aug 4 - Aug 5
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in South Main
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Candlewood Suites Houston Medical Center by IHG | 7.4 Good 889 reviews | View | ||||||
 Comfort Suites Houston near Medical Center- NRG Stadium | 8.8 Excellent 1,001 reviews | View | ||||||
 Wyndham Houston near NRG Park/Medical Center | 7.2 Good 1,381 reviews | View | ||||||
 Wingate Houston near NRG Park/Medical Center | 6.6 1,003 reviews | View | ||||||
 Quality Inn & Suites NRG Park - Medical Center | 6.6 1,012 reviews | View |
Check out reviews of South Main hotels guests love
La Quinta Inn & Suites by Wyndham Houston Bush IAH South
8/10 Good
Find out more about South Main