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Hotels in South San Francisco

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Days Inn by Wyndham San Francisco S/Oyster Point Airport

Days Inn by Wyndham San Francisco S/Oyster Point Airport
2.0 star property
Paradise Valley
7.8 out of 10, Good, (29 reviews)
This South San Francisco hotel offers peaceful accommodations near SFO Museum and Cow Palace. Enjoy complimentary WiFi, breakfast, and airport transfers. Hiking trails beckon outdoor enthusiasts, while Chase Center is just a short drive away.
The price is $82
$99 total
includes taxes & fees
May 31 - Jun 1
Days Inn by Wyndham San Francisco S/Oyster Point Airport

Travelers Inn

Travelers Inn
2.0 star property
South San Francisco
7.6 out of 10, Good, (586 reviews)
Experience convenience at this South San Francisco motel with free WiFi and parking. Located a 12-minute walk from the Metro Station and 11 minutes from SFO, it's near Serramonte Center and Cow Palace. The 24-hour front desk ensures assistance whenever needed.
The price is $114
$133 total
includes taxes & fees
May 26 - May 27
Travelers Inn

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North
2.0 star property
South San Francisco
6.0 out of 10, (3,652 reviews)
Splash in the outdoor pool or grab a bite at the on-site restaurant. Free WiFi and airport shuttle make travel seamless. Just a short drive from Oracle Park, Chase Center, and San Francisco Bay, with SFO Museum nearby.
The price is $64
$76 total
includes taxes & fees
May 26 - May 27
Travelodge by Wyndham San Francisco Airport North

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.2 out of 10, Good, (17 reviews)
Just 8 minutes from SFO Airport, this South San Francisco guesthouse offers convenient access to downtown attractions. Walk to South San Francisco Station or drive minutes to Chase Center. Unwind in rooms with complimentary WiFi and in-room coffeemakers.
The price is $74
$162 total
includes taxes & fees
May 26 - May 27
Miller Apartments

Park Pointe Hotel

Park Pointe Hotel
2.0 star property
South San Francisco
5.8 out of 10, (1,007 reviews)
This serene hotel offers a peaceful atmosphere near SFO Museum and San Francisco Bay. King Sun restaurant serves international cuisine on-site. Walk to South San Francisco Station or drive to Oracle Park and downtown attractions while enjoying free parking.
The price is $70
$83 total
includes taxes & fees
May 26 - May 27
Park Pointe Hotel

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (1,003 reviews)
Minutes from San Francisco International Airport with a 14-minute walk to South San Francisco Station. Enjoy free WiFi and parking at this convenient motel. Guests appreciate the helpful staff while SFO Museum and Cow Palace attractions are nearby.
The price is $120
$140 total
includes taxes & fees
May 26 - May 27
Airport Inn

Hotel Focus SFO

Hotel Focus SFO
3.0 star property
The East Side
7.6 out of 10, Good, (1,593 reviews)
Free airport shuttle makes travel stress-free at this South San Francisco hotel. Enjoy complimentary WiFi and on-the-go breakfast daily. Within walking distance of South San Francisco Station and a short drive to SFO Museum.
The price is $98
$115 total
includes taxes & fees
Jun 7 - Jun 8
Hotel Focus SFO

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,003 reviews)
This serene hotel sits just minutes from San Francisco International Airport with free WiFi and parking. Walk to South San Francisco Station or drive to downtown attractions. The friendly staff ensures peaceful stays in clean, comfortable rooms.
The price is $89
$105 total
includes taxes & fees
May 26 - May 27
Inn By The SFO

Royal Inn

Royal Inn
2.0 star property
South San Francisco
6.8 out of 10, (135 reviews)
Just 10 minutes from San Francisco State University and Golden Gate Park, this South San Francisco motel offers complimentary WiFi and parking. Close to Serramonte Center and Cow Palace, with the Metro Station only 14 minutes away by foot.
The price is $100
$117 total
includes taxes & fees
May 26 - May 27
Royal Inn

Americana Inn

Americana Inn
2.5 star property
South San Francisco
8.0 out of 10, Very Good, (318 reviews)
This South San Francisco motel provides free WiFi and parking just 9 minutes from SFO Airport. Close to SFO Museum and Serramonte Center, with easy access to Chase Center and Oracle Park via nearby metro stations.
The price is $126
$147 total
includes taxes & fees
Jun 18 - Jun 19
Americana Inn

Larkspur Landing Extended Stay Suites South San Francisco

Larkspur Landing Extended Stay Suites South San Francisco
3.0 star property
The East Side
7.6 out of 10, Good, (1,004 reviews)
This tranquil hotel offers free self-serve breakfast and WiFi, with comfortable suites just 14 minutes' walk from South San Francisco Station. Oracle Park and Moscone Convention Center are a short drive away, while the fitness center helps maintain your routine.
The price is $121
$142 total
includes taxes & fees
May 30 - May 31
Larkspur Landing Extended Stay Suites South San Francisco

Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.8 out of 10, Excellent, (2,136 reviews)
Wake up to stunning San Francisco Bay views at this South San Francisco hotel offering a free airport shuttle and American cuisine at The Commons. Just 9 minutes from SFO with easy access to Moscone Convention Center, guests praise the spotless rooms and attentive staff.
The price is $114
$136 total
includes taxes & fees
May 31 - Jun 1
Sonesta Select San Francisco Airport Oyster Point Waterfront

Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel
3.0 star property
South San Francisco
8.4 out of 10, Very Good, (1,818 reviews)
This business-friendly hotel offers convenient perks including free breakfast and a fitness center just minutes from SFO airport. Visit San Francisco Bay or Chase Center with easy access, and return to clean rooms with attentive staff always ready to assist travelers.
The price is $109
$128 total
includes taxes & fees
Jun 13 - Jun 14
Best Western Plus Grosvenor Airport Hotel

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
3.0 star property
The East Side
9.0 out of 10, Wonderful, (491 reviews)
Newly renovated hotel with complimentary breakfast sits just 4 miles from SFO Airport, offering scheduled shuttle service. Close to Chase Center and San Francisco Bay, this contemporary space features clean rooms, a fitness center, and friendly, attentive staff.
The price is $122
$144 total
includes taxes & fees
May 30 - May 31
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North
3.0 star property
The East Side
8.6 out of 10, Excellent, (1,008 reviews)
Step into tranquility at this South San Francisco hotel, just a 13-minute walk from the station. The convenient location puts you close to shops, restaurants, and major attractions. Rooms include microwaves and refrigerators, while a fitness center and restaurant keep you energized.
The price is $92
$108 total
includes taxes & fees
May 31 - Jun 1
Hilton Garden Inn San Francisco Arpt North

DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd
4.0 star property
South San Francisco
8.4 out of 10, Very Good, (2,302 reviews)
Escape the busy travel hustle in this serene hotel just 7 minutes from SFO. Free airport shuttle, comfortable beds, and helpful staff create a peaceful retreat. Unwind at the bar or maintain your routine in the fitness center after exploring nearby attractions.
The price is $118
$139 total
includes taxes & fees
May 31 - Jun 1
DoubleTree by Hilton San Francisco South Airport Blvd

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
4.0 star property
Oyster Point
9.2 out of 10, Wonderful, (1,005 reviews)
Experience waterfront tranquility at this South San Francisco hotel with convenient access to SFO. The indoor pool and 24-hour fitness center offer relaxation, while AC Waterfront Lounge serves local cuisine. Just a short drive from San Francisco Bay and Moscone Convention Center.
The price is $134
$160 total
includes taxes & fees
May 30 - May 31
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

Comfort Inn and Suites San Francisco Airport North

Comfort Inn and Suites San Francisco Airport North
2.5 star property
The East Side
7.8 out of 10, Good, (1,003 reviews)
Just 7.1 km from SFO, this hotel offers complimentary shuttle service, daily buffet breakfast, and WiFi. South San Francisco Station is a 6-minute walk away, while Moscone Convention Center and San Francisco Bay are a short drive from this comfortable base.
The price is $108
$127 total
includes taxes & fees
May 29 - May 30
Comfort Inn and Suites San Francisco Airport North

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side
8.8 out of 10, Excellent, (1,440 reviews)
Just minutes from San Francisco International Airport with shuttle service and walking distance to South San Francisco Station. Enjoy the indoor pool, 24-hour fitness center, and restaurant with bar after a busy day. Fellow travelers praise the helpful staff.
The price is $143
$168 total
includes taxes & fees
May 31 - Jun 1
Embassy Suites by Hilton San Francisco Airport Oyster Point

Hampton Inn San Francisco Airport

Hampton Inn San Francisco Airport
2.5 star property
The East Side
8.8 out of 10, Excellent, (1,003 reviews)
The price is $115
$136 total
includes taxes & fees
Jun 5 - Jun 6
Hampton Inn San Francisco Airport
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Check out hotels with a pool in South San Francisco

You may also like pet-friendly hotels in South San Francisco

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit South San Francisco?

Our prices for hotels in South San Francisco are cheapest in January
Price trends for hotels in South San Francisco
Pricing is based on two traveler single night rates
View properties in May
Currently viewing crowd sizes and weather for May.
Typical weather for South San Francisco
May
High 17°C / low 11°C. Sunny most days.
View properties in May
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May, no crowd data, average high temperature 17 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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July, no crowd data, average high temperature 19 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 20 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 20 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 19 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 17 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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December, no crowd data, average high temperature 14 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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January, no crowd data, average high temperature 14 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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February, no crowd data, average high temperature 15 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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March, no crowd data, average high temperature 15 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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April, no crowd data, average high temperature 16 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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Top neighborhoods in South San Francisco

Downtown South San Francisco

Downtown South San Francisco buzzes with a blend of biotech innovation and cultural diversity. Corporate towers and colorful murals tell the story of this unique business hub. You'll find authentic taquerias, dim sum houses, and Filipino eateries nestled between modern office campuses along Grand Avenue. The neighborhood comes alive during weekdays when professionals fill its plazas and restaurants. Getting around is a breeze with nearby BART and Caltrain stations connecting you to San Francisco proper and beyond. Business hotels cater mostly to corporate travelers with practical amenities. The area quiets down after work hours, offering a genuine glimpse into Bay Area life away from tourist crowds.

Oyster Point

Oyster Point balances sleek biotech campuses with stunning San Francisco Bay views. The waterfront promenade offers perfect spots for watching waves crash against the shore or catching a beautiful sunset. Modern plazas feature public art installations while walking paths showcase both cutting-edge architecture and natural bay ecosystems. Business travelers appreciate the corporate hotels with meeting facilities and convenient access to office buildings. Dining options cater primarily to weekday lunch crowds, with most establishments closing early evening. The area is best explored by car, though waterfront paths provide scenic strolling opportunities away from the corporate hustle.

The East Side

The East Side delivers authentic local life away from San Francisco's tourist traps. Catch Bay views from San Bruno Point Park or explore diverse family-owned restaurants along Grand Avenue serving up killer tacos and pho. This residential neighborhood mixes Hispanic and Asian influences that shine through local markets and casual eateries. Budget travelers appreciate the affordable motels and extended-stay options that cost way less than downtown San Francisco. Buses connect to BART and Caltrain, though having wheels helps. Most spots close early, so plan your food adventures accordingly.

Paradise Valley

Paradise Valley offers a peaceful retreat from San Francisco's bustle while keeping you close to the action. This quiet residential neighborhood in South San Francisco balances suburban calm with convenient access to nearby attractions. Take a stroll through San Bruno Point Park or venture to local spots like K1 Speed for some indoor racing fun. Budget-friendly accommodations make Paradise Valley an appealing base for Bay Area exploration. The neighborhood's proximity to San Francisco International Airport and major highways ensures easy connections throughout the region. With ample street parking and minimal crowds, you'll appreciate this low-key alternative to the city's more hectic districts.

Top landmarks in South San Francisco

Learn more about South San Francisco

Look beyond the iconic 'South San Francisco The Industrial City' sign crowning Sign Hill Park for a city with its own distinct identity. Grand Avenue serves up a global feast of family-run eateries where locals debate the merits of each dumpling house. San Bruno Mountain offers hiking trails with sweeping Bay views that explain why residents tolerate the fog. See's Candies factory tours satisfy sweet tooths, while K1 Speed delivers indoor racing thrills. The Convention Center hosts events that draw visitors who are surprised to discover this isn't simply San Francisco's southern neighborhood. Despite tripling in population since World War II, 'South City' maintains its working-class roots while embracing its role as a Peninsula destination in its own right.

Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀
Open Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

Check out reviews of South San Francisco hotels guests love

Frequently asked questions

What accommodations do travelers like in South San Francisco?
Can I book refundable accommodations in South San Francisco?
If you need the flexibility to change your travel plans to South San Francisco, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in South San Francisco if I want a vacation rental instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 26 vacation homes. In addition, you can choose from 12 apartments.
What will the weather in South San Francisco be like during my visit?
The warmest months in South San Francisco are usually September and August with an average temp of 62°F. February and January are the chilliest months when the average temp is 53°F. The rainiest months are December and January.
Why should I book my South San Francisco accommodation with Hotels.com?
There are lots of reasons to book your South San Francisco trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.