Hotels in South San Francisco

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La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.2 out of 10, Very Good, (2,029 reviews)
Just 5 minutes from SFO, this hotel offers a peaceful retreat with an outdoor pool and 24-hour fitness center. Enjoy complimentary breakfast before exploring nearby attractions or catching the free airport shuttle. Walking distance to South San Francisco Station.
The price is $96
$113 total
includes taxes & fees
Jul 19 - Jul 20
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel
3.0 star property
South San Francisco
8.4 out of 10, Very Good, (1,853 reviews)
This business-friendly hotel offers convenient perks including free breakfast and a fitness center just minutes from SFO airport. Visit San Francisco Bay or Chase Center with easy access, and return to clean rooms with attentive staff always ready to assist travelers.
The price is $109
$128 total
includes taxes & fees
Aug 1 - Aug 2
Best Western Plus Grosvenor Airport Hotel

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side
8.8 out of 10, Excellent, (1,606 reviews)
Just minutes from San Francisco International Airport with shuttle service and walking distance to South San Francisco Station. Enjoy the indoor pool, 24-hour fitness center, and restaurant with bar after a busy day. Fellow travelers praise the helpful staff.
The price is $139
$163 total
includes taxes & fees
Aug 1 - Aug 2
Embassy Suites by Hilton San Francisco Airport Oyster Point

DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd
4.0 star property
South San Francisco
8.4 out of 10, Very Good, (2,364 reviews)
Escape the busy travel hustle in this serene hotel just 7 minutes from SFO. Free airport shuttle, comfortable beds, and helpful staff create a peaceful retreat. Unwind at the bar or maintain your routine in the fitness center after exploring nearby attractions.
The price is $122
$144 total
includes taxes & fees
Jul 25 - Jul 26
DoubleTree by Hilton San Francisco South Airport Blvd

Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.8 out of 10, Excellent, (2,245 reviews)
Wake up to stunning San Francisco Bay views at this South San Francisco hotel offering a free airport shuttle and American cuisine at The Commons. Just 9 minutes from SFO with easy access to Moscone Convention Center, guests praise the spotless rooms and attentive staff.
The price is $110
$131 total
includes taxes & fees
Jul 26 - Jul 27
Sonesta Select San Francisco Airport Oyster Point Waterfront

Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North
3.0 star property
The East Side
8.6 out of 10, Excellent, (1,003 reviews)
Step into tranquility at this South San Francisco hotel, just a 13-minute walk from the station. The convenient location puts you close to shops, restaurants, and major attractions. Rooms include microwaves and refrigerators, while a fitness center and restaurant keep you energized.
The price is $98
$115 total
includes taxes & fees
Jul 26 - Jul 27
Hilton Garden Inn San Francisco Arpt North

Four Points by Sheraton Hotel & Suites San Francisco Airport

Four Points by Sheraton Hotel & Suites San Francisco Airport
3.0 star property
South San Francisco
7.8 out of 10, Good, (1,000 reviews)
Relax in this South San Francisco hotel where free WiFi keeps you connected while the fitness center helps maintain your workout routine. Just a 15-minute drive from Moscone Convention Center and within walking distance of South San Francisco Station.
The price is $103
$121 total
includes taxes & fees
Jul 31 - Aug 1
Four Points by Sheraton Hotel & Suites San Francisco Airport

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
4.0 star property
Oyster Point
9.2 out of 10, Wonderful, (1,002 reviews)
Experience waterfront tranquility at this South San Francisco hotel with convenient access to SFO. The indoor pool and 24-hour fitness center offer relaxation, while AC Waterfront Lounge serves local cuisine. Just a short drive from San Francisco Bay and Moscone Convention Center.
The price is $127
$151 total
includes taxes & fees
Jul 24 - Jul 25
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
3.0 star property
The East Side
9.0 out of 10, Wonderful, (515 reviews)
Newly renovated hotel with complimentary breakfast sits just 4 miles from SFO Airport, offering scheduled shuttle service. Close to Chase Center and San Francisco Bay, this contemporary space features clean rooms, a fitness center, and friendly, attentive staff.
The price is $122
$143 total
includes taxes & fees
Jul 24 - Jul 25
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North
2.0 star property
South San Francisco
6.0 out of 10, (3,864 reviews)
Splash in the outdoor pool or grab a bite at the on-site restaurant. Free WiFi and airport shuttle make travel seamless. Just a short drive from Oracle Park, Chase Center, and San Francisco Bay, with SFO Museum nearby.
The price is $67
$80 total
includes taxes & fees
Jul 27 - Jul 28
Travelodge by Wyndham San Francisco Airport North

Comfort Inn and Suites San Francisco Airport North

Comfort Inn and Suites San Francisco Airport North
2.5 star property
The East Side
7.8 out of 10, Good, (1,002 reviews)
Just 7.1 km from SFO, this hotel offers complimentary shuttle service, daily buffet breakfast, and WiFi. South San Francisco Station is a 6-minute walk away, while Moscone Convention Center and San Francisco Bay are a short drive from this comfortable base.
The price is $102
$120 total
includes taxes & fees
Aug 14 - Aug 15
Comfort Inn and Suites San Francisco Airport North

Home2 Suites by Hilton San Francisco Airport North

Home2 Suites by Hilton San Francisco Airport North
3.0 star property
The East Side
9.0 out of 10, Wonderful, (1,234 reviews)
Just minutes from SFO Airport with complimentary shuttle service, this hotel offers free daily buffet breakfast and WiFi. Walk to South San Francisco Station for city access, or drive to Oracle Park and Chase Center within 15 minutes.
The price is $130
$152 total
includes taxes & fees
Aug 2 - Aug 3
Home2 Suites by Hilton San Francisco Airport North

Holiday Inn Express San Francisco-Airport North by IHG

Holiday Inn Express San Francisco-Airport North by IHG
2.5 star property
South San Francisco
8.2 out of 10, Very Good, (1,000 reviews)
Wake up to a free buffet breakfast at this South San Francisco hotel with complimentary airport shuttles just minutes from SFO. Rooms include refrigerators and microwaves, while a fitness center and hot tub help you unwind after exploring nearby attractions.
The price is $95
$124 total
includes taxes & fees
Aug 2 - Aug 3
Holiday Inn Express San Francisco-Airport North by IHG

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.4 out of 10, Very Good, (1,207 reviews)
Steps from San Francisco Bay, this hotel offers a refreshing outdoor pool and hot tub. Each room includes handy microwaves and refrigerators. A free airport shuttle, fitness center, and complimentary breakfast make exploring nearby attractions effortless.
The price is $116
$138 total
includes taxes & fees
Aug 16 - Aug 17
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Hampton Inn San Francisco Airport

Hampton Inn San Francisco Airport
2.5 star property
The East Side
8.6 out of 10, Excellent, (1,003 reviews)
The price is $110
$131 total
includes taxes & fees
Aug 2 - Aug 3
Hampton Inn San Francisco Airport

Hotel Focus SFO

Hotel Focus SFO
3.0 star property
The East Side
7.6 out of 10, Good, (1,629 reviews)
Free airport shuttle makes travel stress-free at this South San Francisco hotel. Enjoy complimentary WiFi and on-the-go breakfast daily. Within walking distance of South San Francisco Station and a short drive to SFO Museum.
The price is $89
$105 total
includes taxes & fees
Jul 19 - Jul 20
Hotel Focus SFO

Hotel Nova SFO

Hotel Nova SFO
2.5 star property
South San Francisco
8.6 out of 10, Excellent, (1,002 reviews)
The price is $120
$140 total
includes taxes & fees
Jul 31 - Aug 1
Hotel Nova SFO

Larkspur Landing Extended Stay Suites South San Francisco

Larkspur Landing Extended Stay Suites South San Francisco
3.0 star property
The East Side
7.6 out of 10, Good, (1,000 reviews)
This tranquil hotel offers free self-serve breakfast and WiFi, with comfortable suites just 14 minutes' walk from South San Francisco Station. Oracle Park and Moscone Convention Center are a short drive away, while the fitness center helps maintain your routine.
The price is $124
$146 total
includes taxes & fees
Jul 31 - Aug 1
Larkspur Landing Extended Stay Suites South San Francisco

Rodeway Inn South San Francisco Airport

Rodeway Inn South San Francisco Airport
2.0 star property
South San Francisco
7.2 out of 10, Good, (1,001 reviews)
Modern accommodations near San Francisco Intl Airport with free WiFi and parking. Just 7 minutes from SFO Museum and within walking distance of South San Francisco Station. Travelers appreciate the helpful 24-hour staff and secure surroundings.
The price is $84
$99 total
includes taxes & fees
Aug 14 - Aug 15
Rodeway Inn South San Francisco Airport

Days Inn by Wyndham San Francisco S/Oyster Point Airport

Days Inn by Wyndham San Francisco S/Oyster Point Airport
2.0 star property
Paradise Valley
8.0 out of 10, Very Good, (60 reviews)
This South San Francisco hotel offers peaceful accommodations near SFO Museum and Cow Palace. Enjoy complimentary WiFi, breakfast, and airport transfers. Hiking trails beckon outdoor enthusiasts, while Chase Center is just a short drive away.
The price is $101
$125 total
includes taxes & fees
Jul 31 - Aug 1
Days Inn by Wyndham San Francisco S/Oyster Point Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check out pet-friendly hotels in South San Francisco

You may also like hotels with pools in South San Francisco

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit South San Francisco?

Our prices for hotels in South San Francisco are cheapest in January
Price trends for hotels in South San Francisco
Pricing is based on two traveler single night rates
View properties in July
Currently viewing crowd sizes and weather for July.
Typical weather for South San Francisco
July
High 19°C / low 13°C. Sunny most days.
View properties in July
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July, no crowd data, average high temperature 19 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 20 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 20 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 19 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 17 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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December, no crowd data, average high temperature 14 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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January, no crowd data, average high temperature 14 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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February, no crowd data, average high temperature 15 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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March, no crowd data, average high temperature 15 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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April, no crowd data, average high temperature 16 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 17 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 19 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Top neighborhoods in South San Francisco

Downtown South San Francisco

Downtown South San Francisco buzzes with a blend of biotech innovation and cultural diversity. Corporate towers and colorful murals tell the story of this unique business hub. You'll find authentic taquerias, dim sum houses, and Filipino eateries nestled between modern office campuses along Grand Avenue. The neighborhood comes alive during weekdays when professionals fill its plazas and restaurants. Getting around is a breeze with nearby BART and Caltrain stations connecting you to San Francisco proper and beyond. Business hotels cater mostly to corporate travelers with practical amenities. The area quiets down after work hours, offering a genuine glimpse into Bay Area life away from tourist crowds.

Oyster Point

Oyster Point balances sleek biotech campuses with stunning San Francisco Bay views. The waterfront promenade offers perfect spots for watching waves crash against the shore or catching a beautiful sunset. Modern plazas feature public art installations while walking paths showcase both cutting-edge architecture and natural bay ecosystems. Business travelers appreciate the corporate hotels with meeting facilities and convenient access to office buildings. Dining options cater primarily to weekday lunch crowds, with most establishments closing early evening. The area is best explored by car, though waterfront paths provide scenic strolling opportunities away from the corporate hustle.

The East Side

The East Side delivers authentic local life away from San Francisco's tourist traps. Catch Bay views from San Bruno Point Park or explore diverse family-owned restaurants along Grand Avenue serving up killer tacos and pho. This residential neighborhood mixes Hispanic and Asian influences that shine through local markets and casual eateries. Budget travelers appreciate the affordable motels and extended-stay options that cost way less than downtown San Francisco. Buses connect to BART and Caltrain, though having wheels helps. Most spots close early, so plan your food adventures accordingly.

Paradise Valley

Paradise Valley offers a peaceful retreat from San Francisco's bustle while keeping you close to the action. This quiet residential neighborhood in South San Francisco balances suburban calm with convenient access to nearby attractions. Take a stroll through San Bruno Point Park or venture to local spots like K1 Speed for some indoor racing fun. Budget-friendly accommodations make Paradise Valley an appealing base for Bay Area exploration. The neighborhood's proximity to San Francisco International Airport and major highways ensures easy connections throughout the region. With ample street parking and minimal crowds, you'll appreciate this low-key alternative to the city's more hectic districts.

Top landmarks in South San Francisco

Learn more about South San Francisco

Look beyond the iconic 'South San Francisco The Industrial City' sign crowning Sign Hill Park for a city with its own distinct identity. Grand Avenue serves up a global feast of family-run eateries where locals debate the merits of each dumpling house. San Bruno Mountain offers hiking trails with sweeping Bay views that explain why residents tolerate the fog. See's Candies factory tours satisfy sweet tooths, while K1 Speed delivers indoor racing thrills. The Convention Center hosts events that draw visitors who are surprised to discover this isn't simply San Francisco's southern neighborhood. Despite tripling in population since World War II, 'South City' maintains its working-class roots while embracing its role as a Peninsula destination in its own right.

A large, modern bridge with a unique design against a clear blue sky.
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Frequently asked questions

What accommodations do travelers like in South San Francisco?
Can I book refundable accommodations in South San Francisco?
If you need the flexibility to change your travel plans to South San Francisco, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in South San Francisco if I want a vacation rental instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 25 vacation homes. In addition, you can choose from 13 apartments.
What will the weather in South San Francisco be like during my visit?
The warmest months in South San Francisco are usually September and August with an average temp of 62°F. February and January are the chilliest months when the average temp is 53°F. The rainiest months are December and January.
Why should I book my South San Francisco accommodation with Hotels.com?
There are lots of reasons to book your South San Francisco trip with us: our free cancellations on selected hotels gives you flexibility, and with One Keyā„¢, our rewards program, you will be able to earn and use OneKeyCashā„¢* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.