Hotels in Santa Ana
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Top 5 hotels in Santa Ana at a glance
- Casco View Apartments — 3.5-star hotel in Santa Ana. Guest rating: 9.0/10 — Wonderful.
- Hostal La Cigarra — 2-star hotel in Santa Ana. Guest rating: 7.6/10 — Good.
- Hotel República — 2-star hotel in Santa Ana. Guest rating: 6.8/10.
- ART CASCO The Hotel — 2-star hotel in Santa Ana. Guest rating: 6.0/10.
- La Manzana Barrio Vivo by Wynwood — 3-star hotel in Santa Ana. Guest rating: 7.6/10 — Good.
Where to stay in Santa Ana?
Casco View Apartments
Casco View ApartmentsSanta Ana
9.0 out of 10, Wonderful, (102 reviews)
"yes there was laundryroom, iron and nice pool. the stay was very good"
melvin
The price is $75
$113 total
includes taxes & fees
Aug 6 - Aug 7
Hostal La Cigarra
Hostal La CigarraSanta Ana
7.6 out of 10, Good, (73 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
Mark
The price is $31
$34 total
includes taxes & fees
Aug 4 - Aug 5
Hotel República
Hotel RepúblicaSanta Ana
6.8 out of 10, (196 reviews)
"Good location. Walking distance to shops and public transport."
Danilo
The price is $29
$92 total
includes taxes & fees
Aug 4 - Aug 5
ART CASCO The Hotel
ART CASCO The HotelSanta Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking!
The price is really affordable, but the condition of the hotel is not the best"
Eldris
The price is $25
$27 total
includes taxes & fees
Aug 29 - Aug 30
La Manzana Barrio Vivo by Wynwood
La Manzana Barrio Vivo by WynwoodSanta Ana
7.6 out of 10, Good, (18 reviews)
"Very clean and safe property"
Javier Alberto Lindauer
The price is $70
$121 total
includes taxes & fees
Aug 11 - Aug 12
Hotel Riazor
Hotel RiazorSanta Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Del
The price is $27
$30 total
includes taxes & fees
Aug 4 - Aug 5
Hotel Caracas - Casco Viejo
Hotel Caracas - Casco ViejoSanta Ana
9.0 out of 10, Wonderful, (2 reviews)
"It is what you would expect for the $30/ night. Clean bed, and room, a/c worked well, limited water for showers at times, limited hot water. Great location for walking around close to Casco Viejo."
William
The price is $27
$30 total
includes taxes & fees
Aug 18 - Aug 19
Central Hotel Panama Casco Viejo
Central Hotel Panama Casco ViejoSan Felipe, 0.9 km from Santa Ana
9.2 out of 10, Wonderful, (1,006 reviews)
"Great experience, good location and beautiful views"
Vivialy
The price is $165
$182 total
includes taxes & fees
Sep 2 - Sep 3
Tantalo Hotel
Tantalo HotelSan Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (317 reviews)
"Super good location, very nice restaurant."
SUSAN
The price is $93
$103 total
includes taxes & fees
Aug 9 - Aug 10
American Trade Hotel
American Trade HotelSan Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (785 reviews)
"This hotel was amazing; the staff was friendly and helpful. The food was awesome. I will stay there again"
iriela
The price is $177
$195 total
includes taxes & fees
Aug 24 - Aug 25
Hotel Casa Panamá
Hotel Casa PanamáSan Felipe, 0.6 km from Santa Ana
7.6 out of 10, Good, (732 reviews)
"Great location, and nice and helpful staff. "
Liza
The price is $65
$71 total
includes taxes & fees
Aug 19 - Aug 20
Hotel Magnolia Boutique
Hotel Magnolia BoutiqueSan Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (497 reviews)
"Great customer service, wonderful room and great location. "
Sharon
The price is $89
$98 total
includes taxes & fees
Aug 4 - Aug 5
Oasis Hotel
Oasis HotelSan Felipe, 0.6 km from Santa Ana
8.4 out of 10, Very Good, (146 reviews)
"the hotel was great, great location, Claudia very corteous and helpful "
MARGARET
The price is $59
$65 total
includes taxes & fees
Aug 20 - Aug 21
Radisson Hotel Panama Canal
Radisson Hotel Panama CanalAmador, 2.3 km from Santa Ana
8.6 out of 10, Excellent, (1,004 reviews)
"This is always a great place to stay if you want to stay close to the Causeway. Staff is very friendly and helpful. We had a great two night stay!"
Maxima
The price is $94
$103 total
includes taxes & fees
Aug 15 - Aug 16
Marriott Panama Hotel
Marriott Panama Hotel2.1 km from Santa Ana
9.0 out of 10, Wonderful, (1,002 reviews)
"There is good staff. Rooms are top rated"
Jovanny Ariel
The price is $161
$177 total
includes taxes & fees
Aug 16 - Aug 17
Hotel Caribe
Hotel CaribeCalidonia, 1.2 km from Santa Ana
7.6 out of 10, Good, (325 reviews)
"Nice clean, safe hotel in a great location."
James
The price is $42
$46 total
includes taxes & fees
Aug 12 - Aug 13
Hotel Marparaiso
Hotel MarparaisoCalidonia, 1.7 km from Santa Ana
7.8 out of 10, Good, (191 reviews)
"I love the hotel and ever thing about it ,location transport, safe around the hotle ."
Andres
The price is $36
$40 total
includes taxes & fees
Aug 4 - Aug 5
Hotel La Compañía Casco Antiguo
Hotel La Compañía Casco AntiguoSan Felipe, 0.9 km from Santa Ana
9.8 out of 10, Exceptional, (335 reviews)
"Beautiful resort. Great experience. Great location and awesome breakfast"
Michael
The price is $339
$373 total
includes taxes & fees
Aug 20 - Aug 21
Hotel San Felipe
Hotel San FelipeSan Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (430 reviews)
"Lovely place -super nice breakfast and very friendly staff. And a super location!"
Helle
The price is $180
$198 total
includes taxes & fees
Aug 8 - Aug 9
Residencial & Hotel Palazzo
Residencial & Hotel PalazzoCalidonia, 1.4 km from Santa Ana
7.4 out of 10, Good, (145 reviews)
"The room were clean the staff was helpful over all nice"
jameka
The price is $36
$39 total
includes taxes & fees
Sep 1 - Sep 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Santa Ana
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Hotel República | 6.8 196 reviews | View | ||||||
 Casco View Apartments | 9.0 Wonderful 102 reviews | View | ||||||
 Hotel Caracas - Casco Viejo | 9.0 Wonderful 2 reviews | View | ||||||
 Hostal La Cigarra | 7.6 Good 73 reviews | View | ||||||
 La Manzana Barrio Vivo by Wynwood | 7.6 Good 18 reviews | View |
Top landmarks in Santa Ana
Check out reviews of Santa Ana hotels guests love
Dreams Playa Bonita Panama - All Inclusive
10/10 Excellent
Find out more about Santa Ana