Casino Hotels in Panama City

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Sep 20 - Sep 21
Tomorrow
Sep 21 - Sep 22
Next weekend
Sep 25 - Sep 27
In two weeks
Oct 2 - Oct 4

Casino Hotels in Panama City

1. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
$108
$119 total
includes taxes & fees
Sep 21 - Sep 22
Riande Aeropuerto Hotel & Casino

2. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
$139
$139 total
includes taxes & fees
Oct 19 - Oct 20
Megapolis Hotel Panamá

3. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
$109
$120 total
includes taxes & fees
Oct 10 - Oct 11
Decapolis Hotel Panama City

4. ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
Tocumen Airport
$102
$133 total
includes taxes & fees
Sep 21 - Sep 22
ORHO Hotel Boutique 15 Minutes from PTY Airport

5. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
$280
$308 total
includes taxes & fees
Oct 2 - Oct 3
Hotel La Compañía Casco Antiguo

6. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
$110
$121 total
includes taxes & fees
Oct 3 - Oct 4
Courtyard by Marriott Panama Multiplaza Mall

7. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
$169
$186 total
includes taxes & fees
Oct 10 - Oct 11
Marriott Panama Hotel

8. JW Marriott Panama

JW Marriott Panama
San Francisco
$263
$290 total
includes taxes & fees
Oct 4 - Oct 5
JW Marriott Panama

9. Hotel Mio Panama

Hotel Mio Panama
Bella Vista
$56
$62 total
includes taxes & fees
Sep 24 - Sep 25
Hotel Mio Panama

10. Hotel Milan

Hotel Milan
Bella Vista
$40
$44 total
includes taxes & fees
Sep 22 - Sep 23
Hotel Milan

11. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
$143
$157 total
includes taxes & fees
Sep 29 - Sep 30
Renaissance Panama City Hotel

12. Hilton Panama

Hilton Panama
Bella Vista
$245
$270 total
includes taxes & fees
Oct 9 - Oct 10
Hilton Panama

13. Yoo Panama Luxury Ocean View Apartment

Yoo Panama Luxury Ocean View Apartment
Bella Vista
$124
$136 total
includes taxes & fees
Oct 15 - Oct 16
Yoo Panama Luxury Ocean View Apartment

14. Novotel Panama City

Novotel Panama City
Bella Vista
$88
$97 total
includes taxes & fees
Oct 18 - Oct 19
Novotel Panama City

15. Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
Bella Vista
$72
$107 total
includes taxes & fees
Sep 29 - Sep 30
Hotel Dann Carlton Marinn Place Panama Financial District

16. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
$98
$108 total
includes taxes & fees
Oct 2 - Oct 3
Courtyard by Marriott Panama Metromall

17. La Concordia Boutique Hotel

La Concordia Boutique Hotel
Casco Viejo
$202
$222 total
includes taxes & fees
Oct 8 - Oct 9
La Concordia Boutique Hotel

18. Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
Bella Vista
$92
$102 total
includes taxes & fees
Sep 21 - Sep 22
Torres de Alba Hotel & Suites

19. Toscana Inn

Toscana Inn
Bella Vista
$64
$71 total
includes taxes & fees
Sep 21 - Sep 22
Toscana Inn

20. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
$92
$99 total
includes taxes & fees
Sep 27 - Sep 28
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
See more properties

Top neighborhoods in Panama City

Casco Viejo

Casco Viejo's cobblestone streets tell Panama's colonial story at every turn. The golden Metropolitan Cathedral and historic theaters create a living museum vibe. Rooftop bars offer spectacular bay views while museums showcase Panama's diverse heritage. Plaza hopping rewards you with hidden architectural gems and cultural performances that bring history to life. The neighborhood serves up everything from fusion cuisine in restored mansions to traditional Panamanian dishes. Boutique hotels occupy colonial buildings with charming courtyards and personalized service. Though compact, comfortable walking shoes are essential for navigating the uneven historic streets.

Bella Vista

Bella Vista balances Panama City's sleek business side with upscale urban living. Gleaming skyscrapers along Avenida Balboa house financial headquarters while trendy spots on Calle Uruguay buzz with after-work crowds. Shop at MultiPlaza Pacific mall, visit Crown Casino, or simply stroll the waterfront promenade for stunning bay views. Getting around is a breeze with two metro stations and plentiful taxis. Dining options range from rooftop restaurants to international cuisine that won't disappoint. High-rise hotels with spectacular views cater to business travelers and tourists who appreciate modern comforts with a side of ocean breeze.

El Cangrejo

El Cangrejo pulses with modern energy around the iconic "El Tornillo" tower, where art meets business in Panama City's cosmopolitan heart. Korean BBQ aromas mingle with coffee scents from sidewalk cafes, while galleries showcase local talent beneath tropical sunshine. Colorful murals splash across office buildings as diverse cultures blend in this trendy district. The neighborhood serves up an eclectic fusion of Korean, Jewish, and Panamanian cuisines in stylish eateries and casual cafes. Modern boutique hotels and upscale business lodging dominate accommodation options. Getting around is a breeze with nearby Metro Line 1 stations, abundant taxis, and pleasantly walkable streets.

Obarrio

Obarrio dazzles with gleaming skyscrapers housing Panama City's financial powerhouses and luxury shopping. Multiplaza Pacific mall tempts with designer boutiques while the business crowd buzzes between meetings. When you're not trying your luck at local casinos, relax at a sophisticated coffeehouse or stroll the wide, clean sidewalks of Calle 50. Hotels range from international chains to boutique properties, with rates reflecting the upscale surroundings. Getting around is a breeze with excellent taxi service, frequent buses along Via España, and the Metro Line 1 connecting directly to Iglesia del Carmen station.

Punta Pacifica

Punta Pacifica's gleaming glass towers and an iconic sail-shaped skyscraper create a skyline that screams luxury with a Pacific Ocean backdrop. Stroll the waterfront promenades where swaying palms frame perfect sunset views, or duck into Multiplaza Pacific Mall to browse designer boutiques in marble-floored splendor. The neighborhood balances business and pleasure with its mix of corporate offices and upscale leisure spots. Dining here means international cuisine with ocean views at rooftop bars and hotel restaurants where reservations are smart moves. High-rise hotels and serviced apartments offer amenities like infinity pools and concierge services. Getting around is easy with abundant taxis and walkable streets, though you won't find much public transit in this polished enclave.

Top landmarks in Panama City

A modern building facade with vertical reflective panels and the word "GUCCI" prominently displayed.
Photo by Fabiola Tile

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
If you want to give your credit card some exercise, head out to Multiplaza Pacific Mall in San Francisco. Splash some more cash at Avenida Balboa, Multicentro Panama, and Pacific Center.
See properties
A marina with numerous boats, a bridge in the background, and lush green hills.

Amador Causeway

9.0/10 (1,902 reviews)
If you're planning a bit of sightseeing head to Amador Causeway— just one of the monuments in Amador. You can also discover the churches and cathedral in the area— your sightseeing tour starts here. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.
See properties
A city skyline with tall buildings along a waterfront.
Photo by Rob Gosse

Cinta Costera

9.2/10 (3,823 reviews)
Cinta Costera is worth a pic or two when discovering Calidonia.
See properties
A nighttime cityscape with illuminated skyscrapers and a river reflecting the lights.

Avenida Balboa

8.8/10 (3,608 reviews)
If you want to give your credit card some exercise, head out to Avenida Balboa in Calidonia. Splash some more cash at Multicentro Panama, Uruguay Street, and Multiplaza Pacific Mall.
See properties
A historic stone tower amidst ruins, surrounded by grassy terrain.

Panama Viejo

9.2/10 (3,752 reviews)
If you're planning a bit of sightseeing head to Panama Viejo— just one of the monuments in Parque Lefevre. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.
See properties

Albrook Shopping Mall

8.6/10 (4,561 reviews)
Don't visit Ancon without stopping off at Albrook Shopping Mall, a top spot for shopaholics. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.
See properties

Fuerte Amador Resort & Marina

9.4/10 (169 reviews)
You can stroll along Fuerte Amador Resort & Marina for relaxing water views when you're in Amador. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you carry on walking you'll get to Panama Cruise Terminal for some more water views.
See properties

Via Espana

8.4/10 (2,902 reviews)
If you want to give your credit card some exercise, head out to Via Espana in Bella Vista. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. Splash some more cash at Uruguay Street, Multicentro Panama, and Avenida Balboa.
See properties