Hotels in Wyatt
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Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1001)
9.4/10
Exceptional
(1001)
- Peaceful highway-adjacent retreat with indoor and outdoor pool options.
The price is $90
$90
$103 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1004)
8.4/10
Very Good
(1004)
- Stay minutes from Central Park at this inviting hotel with an indoor pool and gym.
The price is $76
$76
$86 total
includes taxes & fees
Dec 30 - Dec 31
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (615)
6.6/10
(615)
- Gateway to historic Charleston with easy interstate access and free breakfast.
The price is $62
$62
$69 total
includes taxes & fees
Dec 30 - Dec 31
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (724)
8.4/10
Very Good
(724)
- Enjoy a serene stay in Sikeston, just minutes from Central Park and Depot Museum.
The price is $55
$55
$63 total
includes taxes & fees
Dec 30 - Dec 31
Quality Inn Cairo I-57
Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (274)
6.6/10
(274)
- Convenient Cairo hotel offers comfortable stay with free breakfast and WiFi.
The price is $71
$71
$79 total
includes taxes & fees
Jan 17 - Jan 18, 2026
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1006)
9.4/10
Exceptional
(1006)
- Quiet, dual pool paradise near Central Park in charming Sikeston.
The price is $75
$75
$86 total
includes taxes & fees
Jan 4 - Jan 5, 2026
La Center Motel
La Center Motel
2.0 star property
La Center
7.8 out of 10, Good, (17)
7.8/10
Good
(17)
- Only minutes from the Ohio River Valley, this hotel offers free perks in La Center.
The price is $60
$60
$70 total
includes taxes & fees
Dec 30 - Dec 31
Eagle Inn Charleston
Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105)
6.6/10
(105)
- Stay fit while visiting Charleston with a health club at this convenient motel.
The price is $60
$60
$67 total
includes taxes & fees
Dec 30 - Dec 31
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (283)
8.4/10
Very Good
(283)
- Cozy stay near Central Park with indoor pool, free WiFi, and friendly staff.
The price is $88
$88
$101 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1005)
7.2/10
Good
(1005)
- Enjoy a peaceful night's rest and complimentary breakfast at this quiet Sikeston hotel.
The price is $63
$63
$72 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Country Yard Inn and Suite
Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (121)
6.8/10
(121)
- Enjoy a comfortable base in Sikeston with free perks and 24-hour service.
The price is $53
$53
$64 total
includes taxes & fees
Dec 30 - Dec 31
Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (569)
6.8/10
(569)
- Convenient Sikeston escape with free amenities and easy access to local attractions.
The price is $59
$59
$68 total
includes taxes & fees
Dec 30 - Dec 31
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Wyatt
Pet friendly
Check out reviews of Wyatt hotels guests love
Super 8 by Wyndham Sikeston/Miner Area
10/10 Excellent
"Excellent check-in process! Extremely friendly staff. Room is very adequate. Everything you need. Price was a great bargain."
Best Western Plus Sikeston
10/10 Excellent
"Great place to stay to stop over for the night. Very clean. Great value. "
Days Inn and Suites by Wyndham Sikeston
10/10 Excellent
"Everything was excellent. Verify happy with everything. Stayed 3 weeks for work and already booked 2 more stays."
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
10/10 Excellent
"Affordable and confortable"
Drury Inn & Suites Sikeston, MO
10/10 Excellent
"This our favorite place to stop for a good night sleep. "
Comfort Inn & Suites Sikeston I-55
10/10 Excellent
"Awesome no complaints "
Country Yard Inn and Suite
10/10 Excellent
"Great stay, numerous tv movie channels, check in easy, friendly staff"
Pear Tree Inn Sikeston
10/10 Excellent
"This is our go to when we visit relatives"
Super 8 by Wyndham Charleston/Sikeston East MO
10/10 Excellent
"Thank you "
Frequently asked questions
What hotels do travelers like in Wyatt?
Can I book refundable accommodations in Wyatt?
If you want the flexibility to change your plans to Wyatt, most hotels offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Wyatt be like during my visit?
The warmest months in Wyatt are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.
Why should I book my Wyatt hotel with Hotels.com?
There are plenty of reasons to book your Wyatt travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.