Hotels in Cairo

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Check prices for these dates

Tonight
Sep 7 - Sep 8
Tomorrow
Sep 8 - Sep 9
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Where to stay in Cairo?

Lobby
Standard Room, 2 Double Beds, Non Smoking
Exterior
Lobby

1. Quality Inn Cairo I-57

Quality Inn Cairo I-57
Cairo
$70
$78 total
includes taxes & fees
Oct 2 - Oct 3
Quality Inn Cairo I-57
Room
Breakfast area
Lobby
Lobby

2. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
$60
$66 total
includes taxes & fees
Sep 8 - Sep 9
Super 8 by Wyndham Charleston/Sikeston East MO
Exterior
Lobby sitting area
Room
Breakfast buffet

3. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
$66
$74 total
includes taxes & fees
Sep 9 - Sep 10
The Riverstone Hotel Charleston-Sikeston
Room, 1 King Bed, Non Smoking | View from room
Property entrance
Room
Room, 1 King Bed, Non Smoking | Bathroom

4. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
$77
$85 total
includes taxes & fees
Sep 8 - Sep 9
Eagle Inn Charleston
Basic Double Room | Living area
Basic Double Room | Living area
Front of property
Basic Double Room

5. La Center Motel

La Center Motel
La Center
$54
$63 total
includes taxes & fees
Sep 20 - Sep 21
La Center Motel
House (2 Bedrooms) | Interior
House (2 Bedrooms) | Front of property
House (2 Bedrooms) | Interior
House (2 Bedrooms) | Interior

6. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
Cunningham
$149
$290 total
includes taxes & fees
Sep 8 - Sep 9
Quiet Country Stay: Modern Home Near Paducah
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Our prices for hotels in Cairo are cheapest in September
Price trends for hotels in Cairo
Pricing is based on two traveler single night rates
View properties in September
Typical weather for Cairo
September
High 28°C / low 17°C. Sunny most days.
View properties in September
28°
17°
21°
11°
14°
5°
9°
1°
6°
-2°
8°
-1°
14°
5°
19°
9°
25°
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32°
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Monthly weather averages (˚C)

Top landmarks in Cairo

Fort Defiance State Park

7.4/10 (15 reviews)
Fort Defiance State Park is 2.3 mi (3.7 km) from central Cairo, why not stop by during your stay.
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Learn more about Cairo

Cairo is well-known for its attractions such as Mississippi River and Ohio River Valley. The city has something for everyone including sights like Fort Defiance State Park within a small-town setting.

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A steel bridge with a sunset in the background.

Check out reviews of Cairo hotels guests love

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

10/10 Excellent
"Everything was fine for a one night stay."
Jay 1-night trip
Posted 8 hours ago
The Riverstone Hotel Charleston-Sikeston
La Center Motel

La Center Motel

10/10 Excellent
"Great AC unit in the room!"
Jonathan 1-night trip
Posted 1 month ago
La Center Motel
Eagle Inn Charleston

Eagle Inn Charleston

10/10 Excellent
"Great"
Jackson 1-night trip
Posted 5 months ago
Eagle Inn Charleston

Frequently asked questions

What accommodations do travelers like in Cairo?
Guests like Quality Inn Cairo I-57 and Eagle Inn Charleston.
Can I book refundable accommodations in Cairo?
If you're looking for the flexibility to change your travel plans to Cairo, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I stay in Cairo if I'm looking for an affordable accommodation?
Quality Inn Cairo I-57 is an accommodation you might want to consider that'll save you money.
What will the weather in Cairo be like during my trip?
The warmest months in Cairo are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.
Why should I book my Cairo accommodation with Hotels.com?
There are plenty of reasons to book your Cairo travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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