Hotels in New Madrid

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

This weekend
Aug 7 - Aug 9
Next weekend
Aug 14 - Aug 16

Top 5 hotels in New Madrid at a glance

  1. Super 8 By Wyndham Marston — 2-star hotel in Marston. Guest rating: 8.0/10 — Very Good.
  2. Reelfoot Lake Inn — 2-star hotel in Tiptonville. Guest rating: 7.2/10 — Good.
  3. Travel Inn Marston I-55 by Hotel O — 2.5-star hotel in Marston. Guest rating: 6.0/10.
  4. Holiday Inn Express & Suites Sikeston Southwest by IHG — 2.5-star hotel in Sikeston. Guest rating: 8.8/10 — Excellent.
  5. Hampton Inn Sikeston — 2.5-star hotel in Sikeston. Guest rating: 9.0/10 — Wonderful.

Where to stay in New Madrid?

Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout drapes, WiFi (free)

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very Good, (69 reviews)
Discover comfort at this Marston hotel, just off Interstate 55. Wake up to a complimentary full breakfast before exploring nearby attractions. Free WiFi and parking add value to your stay in this convenient Missouri location.
The price is $83
$95 total
includes taxes & fees
Aug 4 - Aug 5
Super 8 By Wyndham Marston
Standard Room, 2 Double Beds, Non Smoking | Blackout drapes, iron/ironing board (on request), WiFi (free)

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (502 reviews)
The price is $61
$76 total
includes taxes & fees
Aug 23 - Aug 24
Reelfoot Lake Inn
WiFi (free), bed sheets

Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
2.5 star property
Marston
6.0 out of 10, (127 reviews)
The price is $69
$86 total
includes taxes & fees
Sep 2 - Sep 3
Travel Inn Marston I-55 by Hotel O
Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.8 out of 10, Excellent, (489 reviews)
Experience Sikeston from this hotel with free breakfast, WiFi, and parking. Take a morning dip in the indoor pool or hit the fitness center. Near Central Park and Sikeston Depot Museum, guests love the helpful staff and clean rooms.
The price is $97
$110 total
includes taxes & fees
Aug 23 - Aug 24
Holiday Inn Express & Suites Sikeston Southwest by IHG
Exterior

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (601 reviews)
Dive into vacation mode at this welcoming hotel with an indoor pool and fitness center near Central Park. After enjoying the complimentary breakfast, explore Sikeston Depot Museum before returning to relax in modern rooms with free WiFi.
The price is $99
$112 total
includes taxes & fees
Aug 23 - Aug 24
Hampton Inn Sikeston
Property amenity

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (101 reviews)
Located in Sikeston, this hotel offers free breakfast, WiFi, and parking. Take a refreshing swim in the indoor pool or grab a bite at the restaurant. Nearby attractions include Central Park and Sikeston Depot Museum for local exploration.
The price is $110
$125 total
includes taxes & fees
Aug 9 - Aug 10
Fairfield Inn & Suites by Marriott Sikeston
Property amenity

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (19 reviews)
The price is $109
$123 total
includes taxes & fees
Aug 16 - Aug 17
TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top landmarks in New Madrid

River Ridge Winery

8.4/10 (15 reviews)
Travelers might want a tour of River Ridge Winery, just one of the places to visit, and located 0.6 mi (1 km) from central New Madrid.
See properties

Learn more about New Madrid

New Madrid is applauded for its cultural attractions such as New Madrid Historical Museum and Hunter-Dawson State Historic Site.

See all hotels in New Madrid
A cannon on a brick platform by a river, with a steamboat in the background.

Check out reviews of New Madrid hotels guests love

Hampton Inn Sikeston

Hampton Inn Sikeston

8/10 Good
"They didn't have any cups inside the room"
Carla Sue 2-night trip
Posted 2 hours ago
Hampton Inn Sikeston

Frequently asked questions

What hotels do travelers like in New Madrid?
Guests like Super 8 By Wyndham Marston and Travel Inn Marston I-55 by Hotel O.
Can I book refundable accommodations in New Madrid?
If you need the flexibility to change your travel plans to New Madrid, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in New Madrid be like during my vacation?
The warmest months in New Madrid are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 42°F. The rainiest months are March and April.
Why should I book my New Madrid hotel through Hotels.com?
There are plenty of reasons to book your New Madrid travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.