Photo by Visit Greenville, South Carolina
Hotels in Upstate South Carolina
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Upstate South Carolina?

Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & Suites
9.2 out of 10, Wonderful, (1370)
The price is $94
$103 total
includes taxes & fees
Oct 26 - Oct 27
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check out hotels with a hot tub in Upstate South Carolina

Comfort Suites Greenville Airport
Comfort Suites Greenville Airport
9.4 out of 10, Exceptional, (1000)
The price is $108
$122 total
includes taxes & fees
Nov 9 - Nov 10
You may also like pet-friendly hotels in Upstate South Carolina

Hampton Inn Anderson/ Alliance Business Park
Hampton Inn Anderson/ Alliance Business Park
9.2 out of 10, Wonderful, (787)
The price is $114
$126 total
includes taxes & fees
Nov 2 - Nov 3
You can also stay at family-friendly hotels in Upstate South Carolina

Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & Suites
9.2 out of 10, Wonderful, (1370)
The price is $94
$103 total
includes taxes & fees
Oct 26 - Oct 27
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Upstate South Carolina
Top landmarks in Southeastern United States
Learn more about Upstate South Carolina
Upstate South Carolina is well-known for its university life and sports, featuring attractions such as Discovery Island Water Park and Frankie's Fun Park. This family-friendly city has something for everyone including its live music, restaurants, and sights like The Shops at Greenridge and Conestee Nature Preserve.

Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism
Check out reviews of Upstate South Carolina hotels guests love

Drury Inn & Suites Greenville
10/10 Excellent
Frequently asked questions
Keep exploring
- Neighborhoods
- Landmarks
- Amenities
- Hotels close to nearby airports
- Nearby cities
- Top cities in United States of America
- More Hotels
- Most popular destinations
- More ways to book
- Hotels near Falls Park on the Reedy
- Hotels near Bon Secours Wellness Arena
- Hotels near Prisma Health Greenville Memorial Hospital
- Hotels near Clemson University
- Hotels near Spartanburg Memorial Auditorium
- Hotels near Haywood Mall
- Hotels near BMW Performance Center
- Hotels near Greenville Convention Center
- Hotels near The Peace Center
- Hotels near Wofford College
- Hotels near Fred W. Symmes Chapel
- Hotels near Bob Jones University
- Hotels near Devils Fork State Park
- Hotels near Memorial Stadium
- Hotels near Furman University
- Hotels near Table Rock State Park
- Hotels near Fluor Field at the West End
- Hotels near WestGate Mall
- Hotels near Anderson University
- Hotels near Heritage Park
- Hotels with Parking in Upstate South Carolina
- Family Hotels in Upstate South Carolina
- Business Hotels in Upstate South Carolina
- Hotels with Free Breakfast in Upstate South Carolina
- Hotels with a Pool in Upstate South Carolina
- Hotels with a Gym in Upstate South Carolina
- Pet-Friendly Hotels in Upstate South Carolina
- Cheap Hotels in Upstate South Carolina
- Hotels with Kitchens in Upstate South Carolina
- New York Hotels
- Las Vegas Hotels
- Orlando Hotels
- Chicago Hotels
- San Francisco Hotels
- Los Angeles Hotels
- San Diego Hotels
- Miami Hotels
- Houston Hotels
- Boston Hotels
- Pigeon Forge Hotels
- Nashville Hotels
- Gatlinburg Hotels
- Atlanta Hotels
- San Antonio Hotels
- Austin Hotels
- New Orleans Hotels
- Honolulu Hotels
- Dallas Hotels
- Anaheim Hotels
- Spartanburg Marriott
- Holiday Inn Greenville - Woodruff Road by IHG
- Courtyard by Marriott Greenville Haywood Mall
- SpringHill Suites by Marriott Greenville Downtown
- The Shepherd Hotel Downtown Clemson
- Baymont by Wyndham Greenville Woodruff Rd
- Aloft Greenville Downtown
- Lakeside Lodge Clemson
- Quality Inn Seneca Clemson Area US-123
- Hampton Inn & Suites Greenville Airport, SC
- Tru by Hilton Greenville Woodruff Road
- Best Western Greenville Airport Inn
- Hyatt Place Greenville/Haywood
- Hotel Hartness
- Holiday Inn Express & Suites Greenville - Downtown by IHG
- Tru by Hilton Spartanburg
- Courtyard Greenville-Spartanburg by Marriott
- Comfort Inn & Suites Clemson - University Area
- Comfort Suites At WestGate Mall
- Best Western Plus Spartanburg
- Days Inn by Wyndham Clinton / Laurens I-26
- Holiday Inn Express Gaffney by IHG
- Comfort Inn & Suites Greer - Greenville
- Best Western Spartanburg Northwest
- Inn @ Clemson
- Comfort Suites Greenville South
- Baymont by Wyndham Easley/Greenville
- Hampton Inn Gaffney
- Days Inn by Wyndham Easley/Greenville/Clemson Area
- Clemson University's James F. Martin Inn
- Hampton Inn & Suites Seneca-Clemson Area
- Best Western Travelers Rest Greenville
- Comfort Suites Simpsonville - Greenville
- Hampton Inn Clemson-University Area
- The Inn at Patrick Square
- WoodSpring Suites Greenville Simpsonville
- Days Inn by Wyndham Simpsonville
- Best Western Seneca-Clemson
- Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG
- WoodSpring Suites Spartanburg - Duncan
- Hampton Inn Greenville/Travelers Rest
- Rodeway Inn & Suites Walhalla
Most popular destinations
Hotels
- The Waves Tulum
- Hotels in Catalina Island
- Hotel Abu
- Hotels in Martha's Vineyard
- Cheap Hotels in Monterey Wine Country
- Cheap Hotels in Twin Falls
- Hotels in Tobago
- Ocean Maya Royale - Adults Only - All Inclusive
- Hotels in Downtown Charleston
- Hotel Baluartes
- Hotels near Marine Corps Recruit Depot Parris Island
- El Dorado Royale, Catamaran, Cenote, All & More Inclusive Adults Only
- Cheap Hotels in Martinsville
- Hotels in Hamptons
- Hotels in Far Rockaway
- Maxxmarine hotel
- Hotels in Buffalo
- Cheap Hotels in Fort Walton Beach - Destin
- Hotels in Vancouver
- Business Hotels in Mississippi Gulf Coast
- Hotels near Coker College
- Renovated Aloft Cancun
- Hotel Hostal El Farol
- Hotels in Long Beach Island
- Hotels in Bay Area
- Hotel Mexicali
- Cheap Hotels in San Francisco
- Hotels in Maui
- Sheraton Maria Isabel Mexico City Reforma
- Hotels in Las Vegas























































































































































