Photo by Cindy Keese

Hotels in Seneca

your current months are February, 2025 and March, 2025.
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March 2025
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Where to stay in Seneca?

Quality Inn Seneca US-123
Room, 2 Double Beds, Accessible, Non Smoking | Pillowtop beds, desk, laptop workspace, blackout drapes

Quality Inn Seneca US-123

2.5 star property
8.0 out of 10, Very Good, (562)
The price is $91
$110 total
includes taxes & fees
Feb 15 - Feb 16
Quality Inn Seneca US-123
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Seneca

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Pine Ridge Point

Seneca's Pine Ridge Point neighborhood offers attractions including Lake Keowee.

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Pine Ridge Point

Learn more about Seneca

Seneca, well-known for its sports and university life, features attractions such as Blue Ridge Field and Keowee Reservoir. This family-friendly city has something for everyone including its waterfront, coffeehouses, and sights like Lake Keowee and Keowee Key Golf Course.

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View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

Frequently asked questions

What accommodations do travelers like in Seneca?
Tru by Hilton Seneca Clemson, Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area are all properties that our guests really like.
Can I book refundable accommodations in Seneca?
If you want the flexibility to change your travel plans to Seneca, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in Seneca if I want a budget-friendly accommodation?
Two inexpensive options worth considering are Lakeside Lodge Clemson and Tru by Hilton Seneca Clemson.
Where can I stay in Seneca if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 189 vacation homes. In addition, there are 11 apartments and 7 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.