A person in a red jacket and black boots standing on a sandy beach, a dog walking beside them, and another person paddling a kayak in calm water.

Hotels in Salem

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Where to stay in Salem?

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern lobby with a reception desk, seating area, and a vending machine.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

1. Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

$120

$132 total

includes taxes & fees

Oct 11 - Oct 12

A kitchen with a coffee maker, microwave, and refrigerator.

A hotel room with a large bed, a bedside table, a nightstand, and a wall-mounted lamp.

A hotel room with a bed, a desk with a chair, a television, a small table, and a microwave.

A red brick building with a white porch and columns, a door, and windows.

2. Rodeway Inn & Suites Walhalla

Walhalla

$76

$85 total

includes taxes & fees

Nov 5 - Nov 6

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

A reception area with a counter, chairs, and a patterned rug.

3. Hampton Inn & Suites Seneca-Clemson Area

Seneca

$123

$136 total

includes taxes & fees

Oct 8 - Oct 9

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

4. Best Western Seneca-Clemson

Seneca

$94

$103 total

includes taxes & fees

Oct 28 - Oct 29

A modern dining area with a high ceiling, large windows, and a buffet setup.

A swimming pool with lounge chairs and a fence, surrounded by trees.

A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

5. Days Inn by Wyndham Seneca / Clemson Area

Seneca

$83

$91 total

includes taxes & fees

Oct 11 - Oct 12

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

6. Quality Inn Seneca US-123

Seneca

$76

$89 total

includes taxes & fees

Oct 18 - Oct 19

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

A spacious dining area with a long wooden table and patterned upholstered chairs.

7. Lakeside Lodge Clemson

Seneca

$109

$135 total

includes taxes & fees

Oct 8 - Oct 9

A wooden interior with a fireplace, large windows, and outdoor deck.

A lodge with a wooden exterior, a balcony, and a staircase leading to the upper level.

A bedroom with a bed, a desk, a chair, a window, and a door.

A cozy room with a stone fireplace, two wooden rocking chairs, and a large deer painting on the wall.

8. Brook Trout Inn

Sapphire

$186

$208 total

includes taxes & fees

Nov 4 - Nov 5

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

A hotel room with two beds, a desk, a television, and a clock on the wall.

A wall with a decorative design featuring a building, trees, and a sky with clouds.

A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.

9. Inn @ Clemson

Clemson

$89

$99 total

includes taxes & fees

Oct 8 - Oct 9

An outdoor patio area with a fire pit, seating, and string lights.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.

10. Tru by Hilton Seneca Clemson

Seneca

$106

$116 total

includes taxes & fees

Oct 18 - Oct 19

A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

A hotel breakfast area with a self-serve station, including a refrigerator, coffee machine, and fruit display.

A hotel room with a large bed, a desk, a chair, a mirror, and a framed picture on the wall.

A conference room with a large round table, multiple chairs, and a projector.

11. Holiday Inn Express & Suites Clemson by IHG

Clemson

$129

$143 total

includes taxes & fees

Oct 9 - Oct 10

A modern bar area with a menu board, bar stools, and a countertop with various items.

A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.

An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.

A modern dining area with a bar, bar stools, and a patterned rug.

12. Courtyard Marriott Clemson

Clemson

$107

$119 total

includes taxes & fees

Oct 18 - Oct 19

A modern kitchen area with a bar counter and seating.

A vending area with snacks and beverages, including chips and soda.

A modern bar area with high stools and a poolside view.

A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.

13. Hampton Inn Clemson-University Area

Clemson

$110

$122 total

includes taxes & fees

Oct 13 - Oct 14

A long dining table set with plates, glasses, and cutlery, flanked by wooden chairs.

A teal building with a sign reading "H.M.H." and outdoor seating with umbrellas.

A rustic living room with a stone fireplace, leather armchairs, a patterned sofa, and antler decorations.

A bar area with wooden paneling, a counter with stools, and a view of the outdoors through windows.

14. Highlander Mountain House

Downtown Highlands

$195

$214 total

includes taxes & fees

Oct 28 - Oct 29

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.

An outdoor patio with wicker furniture, a round table, and a fountain.

A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

15. The Shepherd Hotel Downtown Clemson

Clemson

$209

$232 total

includes taxes & fees

Oct 13 - Oct 14

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

16. The Abernathy of Clemson

Clemson

$161

$179 total

includes taxes & fees

Oct 18 - Oct 19

A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.

A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

A lobby with seating areas, a reception desk, and a patterned wall.

17. Best Western Plus Clemson Hotel & Conference Center

Clemson

$105

$117 total

includes taxes & fees

Oct 11 - Oct 12

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

A modern restaurant with a marble-top dining table, blue upholstered chairs, and a variety of food items displayed in the background.

A hotel lobby with a long corridor, seating areas, and a reception desk.

A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".

18. The Inn at Patrick Square

Clemson

$149

$165 total

includes taxes & fees

Oct 11 - Oct 12

A swimming pool with lounge chairs and a covered area with tables and chairs.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a microwave.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

A covered porch with a welcome mat, two black Adirondack chairs, and a bench.

19. Carolina Camp Cedar

Pickens

$109

$204 total

includes taxes & fees

Oct 8 - Oct 9

A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.

A gazebo with a tiled roof and a surrounding gravel area.

A gazebo with a tiled roof and wooden pillars, surrounded by a fence and potted plants.

20. Days Inn by Wyndham Clemson

Clemson

$80

$89 total

includes taxes & fees

Oct 8 - Oct 9

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A sunroom with large windows, a ceiling fan, and a coffee table with a vase of flowers.

A kitchen with a refrigerator, white cabinets, a dining area with a table and chairs, and a large window.

A multi-story building with large windows, a balcony, and a tree in front.

A covered patio with wicker furniture and sliding glass doors.

Sunroom & Deck! Golf Retreat in Keowee Key

Salem

$155

per night

$617 total

includes taxes & fees

A wooden gazebo with a roof, surrounded by trees, overlooking a calm lake.

A lakeside view with a sandy beach, lounge chairs, and a row of buildings in the background.

A modern kitchen with white cabinets, a black refrigerator, a teal pendant light, and a marble countertop.

An aerial view of a residential area with houses, a golf course, and a lake in the background.

Lake Front Keowee Condo W/ Balcony & Resort Amenities! 2 Bedroom Condo by RedAwning

Salem

$258

per night

$865 total

includes taxes & fees

A wooden gazebo with a roof and a table and chairs inside, surrounded by trees and overlooking a lake.

A modern building with a prominent wooden entrance canopy, stone pillars, and a clear sky.

A modern living room with a sofa, a coffee table, and a fireplace.

A modern kitchen with a stainless steel sink, pendant lighting, and a view to a living area with a sofa and a staircase.

Tee Times & Lake Days! Luxe Keowee Key Living

Salem

$259

per night

$785 total

includes taxes & fees

A wooden gazebo with a roof and a table and chairs, surrounded by trees and a lake.

A building with a balcony overlooking a dense forest and a body of water.

A lakeside view with boats docked, a wooden bridge, and a covered boat storage area.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a coffee maker.

Condo on Lake Keowee w/ Resort Amenities & Pool!

Salem

$212

per night

$668 total

includes taxes & fees

A wooden gazebo with a roof, surrounded by trees, overlooking a lake.

A private beach with a stone pathway leading to the water, surrounded by trees and a wooden fence.

A sandy beach with a calm lake surrounded by trees.

An indoor swimming pool with clear lanes, a covered roof, and blue and white flags.

Keowee Key Condo w/ Lake Access!

Salem

$316

per night

$863 total

includes taxes & fees

A modern kitchen with white cabinets, a large island, stainless steel appliances, and teal pendant lights.

A kitchen with a granite countertop, white cabinets, and teal pendant lights.

An indoor swimming pool with clear lanes, a high ceiling with skylights, and blue and white triangular flags.

Lake Keowee Resort Condo w/ Balcony & Pool Access!

Salem

$456

per night

$1,272 total

includes taxes & fees

Go beyond your typical stay in Salem

Top neighborhoods in Salem

Turtlehead

Turtlehead

Salem's Turtlehead neighborhood is home to attractions such as Lake Keowee and Chapman Bridge Oconee Bell Preserve.

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Top landmarks in Salem

Devils Fork State Park

9.2/10 (41 reviews)

Devils Fork State Park is 4.7 mi (7.5 km) from central Salem, why not stop by during your stay.

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Keowee Key Golf Course

9.6/10 (7 reviews)

You might want to practice your swing at Keowee Key Golf Course, a golf course located 4.9 mi (7.9 km) from central Salem. If Keowee Key Golf Course doesn't quite scratch your golfing itch, Keowee Springs Golf Course is also nearby.

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Devils Fork Lake Jocassee

Devils Fork Lake Jocassee is 4.6 mi (7.4 km) from central Salem, why not stop by during your stay. If you like Devils Fork Lake Jocassee, you'll love Long Shoals Recreation Area and DAR Monument, both just a short drive away.

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South Beach

If want to top up your tan, you might want to head out to South Beach, located 6 mi (9.7 km) from central Salem. Enjoy the sunset by the shore at North Beach.

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Ultimate Action Sports

10.0/10 (1 review)

Ultimate Action Sports is 2.5 mi (4.1 km) from central Salem, why not stop by during your stay. If you'd also like to explore some of the parks in Salem, Devils Fork Lake Jocassee and DAR Monument are both nearby.

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Boones Creek Oconee Bell Preserve

Boones Creek Oconee Bell Preserve is 2.7 mi (4.4 km) from central Salem, why not stop by during your stay.

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Keowee Key Fitness & Tennis Center

You can catch an event at Keowee Key Fitness & Tennis Center, located 4.7 mi (7.6 km) from central Salem.

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North Beach

If being by the water is a major draw, North Beach is a spot you might want to check out, located 5.1 mi (8.1 km) from central Salem. Enjoy the sunset by the shore at South Beach.

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Learn more about Salem

Salem is well-known for its attractions such as Devils Fork Lake Jocassee and Devils Fork State Park.

See all hotels in Salem

Check out reviews of Salem hotels guests love

Hampton Inn & Suites Seneca-Clemson Area

Seneca

10/10 Exceptional

LuAnn

The Shepherd Hotel Downtown Clemson

Clemson

10/10 Exceptional

Amy

Best Western Seneca-Clemson

Seneca

10/10 Exceptional

Amy

The Inn at Patrick Square

Clemson

10/10 Exceptional

SHARRA

Brook Trout Inn

Sapphire

10/10 Exceptional

Julie

Lakeside Lodge Clemson

Seneca

10/10 Exceptional

Maria

The Abernathy of Clemson

Clemson

10/10 Exceptional

Michele

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A cozy living room with a dining table, sofas, and a chandelier.

A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.

Clemson Memorabilia House

Clemson

10/10 Exceptional

Marissa

A modern living room with a stone fireplace, wooden flooring, and black leather furniture.

A dining area with a wooden table and chairs, a kitchen with white cabinets, and a bedroom with a bed and nightstand.

A bedroom with a large bed, wooden ceiling beams, a ceiling fan, a TV mounted on the wall, and a balcony with a view of trees.

A log cabin with a porch, surrounded by trees.

The Wells Hotel Cashiers

Cashiers

10/10 Exceptional

Norman

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

A cabin in a forest with a small deck and outdoor seating area.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

10/10 Exceptional

Jonathan

A hotel with a stone facade, large windows, and a well-maintained garden.

A bedroom with a large bed, a dark-colored bench, a patterned carpet, and a view of the outside through a glass door.

A person holding a dog in a garden with various plants and a street lamp.

A white robe hanging on a hook, a wooden bench, and a wall-mounted device.

The Park On Main

Downtown Highlands

10/10 Exceptional

Jim

A golf course with a water body, trees, and a distant view of a bridge.

A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.

An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.

A golf course with a clubhouse, surrounded by dense trees and a large body of water.

Clemson University's James F. Martin Inn

Clemson

10/10 Exceptional

Margot

Quality Inn Seneca US-123

Seneca

10/10 Exceptional

Norma

Courtyard Marriott Clemson

Clemson

10/10 Exceptional

Anonymous traveler

A forested area with a fire pit and wooden chairs.

A room with a desk, two chairs, a small table with a vase of flowers, and a view of greenery outside.

A spacious living area with a large window, a wooden dining table, and a cozy seating arrangement.

Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

Highlands

10/10 Exceptional

Jennifer

A white, two-story house with a front porch, surrounded by trees and shrubs.

A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.

A two-story building with a white exterior, a front door, and a balcony.

A bedroom with two beds, a TV, and a fireplace.

Liberty Hall Bed and Breakfast

Pendleton

10/10 Exceptional

William

Frequently Asked Questions

Can I book refundable accommodations in Salem?

If you want the flexibility to change your travel plans to Salem, most properties provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Salem if I want a vacation rental instead of a hotel?

If you want to find a good alternative to a hotel, browse our selection of 42 vacation homes. In addition, there are 25 apartments and 51 condos.

What will the weather in Salem be like during my trip?

The warmest months in Salem are usually July and August with an average temp of 68°F. January and February are the chilliest months when the average temp is 42°F. The rainiest months are December and April.

Why should I book my Salem hotel through Hotels.com?

There are plenty of reasons to book your Salem travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.