4 Star Hotels in Syracuse

November 2026
December 2026

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Oct 23 - Oct 25
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Oct 30 - Nov 1

4 Star Hotels in Syracuse

1. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
$193
$224 total
includes taxes & fees
Nov 13 - Nov 14
Algila' Ortigia Charme Hotel

2. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
Ortigia
$200
$232 total
includes taxes & fees
Nov 5 - Nov 6
Palazzo Artemide - VRetreats, SLH Collection

3. Grande Albergo Alfeo

Grande Albergo Alfeo
Santa Lucia
$86
$98 total
includes taxes & fees
Nov 15 - Nov 16
Grande Albergo Alfeo

4. Charme Hotel Henry's House

Charme Hotel Henry's House
Ortigia
$223
$256 total
includes taxes & fees
Nov 12 - Nov 13
Charme Hotel Henry's House

5. Grand Hotel Villa Politi

Grand Hotel Villa Politi
Grottasanta
$116
$132 total
includes taxes & fees
Nov 15 - Nov 16
Grand Hotel Villa Politi

6. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
Santa Lucia
$102
$116 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Palazzo Cavalieri

7. Mercure Siracusa Prometeo

Mercure Siracusa Prometeo
Neapolis
$95
$119 total
includes taxes & fees
Nov 4 - Nov 5
Mercure Siracusa Prometeo

8. Borgo Pantano

Borgo Pantano
Syracuse
$169
$197 total
includes taxes & fees
Oct 20 - Oct 21
Borgo Pantano

9. UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA
Grottasanta
$149
$170 total
includes taxes & fees
Oct 25 - Oct 26
UNA Hotels One Siracusa Wellness & SPA

10. Hotel Parco delle Fontane

Hotel Parco delle Fontane
Tiche
$114
$130 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Parco delle Fontane

11. Life Hotels Kalaonda Resort

Life Hotels Kalaonda Resort
Syracuse
$108
$123 total
includes taxes & fees
Oct 19 - Oct 20
Life Hotels Kalaonda Resort

12. Hotel Villamare

Hotel Villamare
Syracuse
$145
$165 total
includes taxes & fees
Oct 19 - Oct 20
Hotel Villamare

13. Hotel Centrale

Hotel Centrale
Syracuse
$102
$117 total
includes taxes & fees
Nov 15 - Nov 16
Hotel Centrale

14. Addauro Resort

Addauro Resort
Syracuse
$85
$97 total
includes taxes & fees
Oct 20 - Oct 21
Addauro Resort

15. Albatros Hotel

Albatros Hotel
Syracuse
$103
$117 total
includes taxes & fees
Oct 27 - Oct 28
Albatros Hotel

16. Residence Archimede

Residence Archimede
Syracuse
$125
$143 total
includes taxes & fees
Oct 24 - Oct 25
Residence Archimede

17. Eureka Palace Hotel Spa

Eureka Palace Hotel Spa
Syracuse
$86
$98 total
includes taxes & fees
Nov 16 - Nov 17
Eureka Palace Hotel Spa

18. Villa Fanusa

Villa Fanusa
Syracuse
$94
$107 total
includes taxes & fees
Oct 19 - Oct 20
Villa Fanusa

19. Casal Sikelio

Casal Sikelio
Syracuse
$144
$164 total
includes taxes & fees
Oct 27 - Oct 28
Casal Sikelio

20. Hotel Relax

Hotel Relax
Epipoli
$138
$157 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Relax
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Top neighborhoods in Syracuse

Ortigia

Ortigia's ancient limestone streets tell 2,700 years of Mediterranean stories through every weathered stone. Greek temple ruins stand beside a stunning Baroque cathedral, while the 13th-century Castello Maniace guards this tiny island's tip. The mystical Fonte Aretusa freshwater spring creates a papyrus grove right beside the crystal-clear Ionian Sea. Waterfront trattorias serve fresh seafood and Sicilian classics while you watch fishing boats bobbing at sunset. The compact 1km island is best explored on foot through narrow medieval lanes. Historic palazzos converted to boutique hotels offer authentic stays with sea views from wrought-iron balconies.

Neapolis

Step back in time at Syracuse's Neapolis, where ancient Greek and Roman civilizations come alive through remarkable ruins. The Greek Theater carved into limestone hills offers stunning harbor views, while the Roman Amphitheater reveals gladiatorial heritage. Don't miss the Ear of Dionysius cave where whispers magically amplify, or the Paradise Quarry gardens blooming with Mediterranean flora. Getting around requires walking on uneven ancient paths, with limited bus service connecting to Syracuse center. Pack a lunch or visit the small café near the entrance since dining options are minimal. The archaeological park closes at sunset, so plan your visit during daylight hours to fully experience this extraordinary outdoor museum.

Santa Lucia

Santa Lucia delivers an epic history lesson with every step through its honey-colored streets. The ancient neighborhood showcases Greek ruins, the legendary Tomb of Archimedes, and the stunning Church of Santa Lucia alla Badia with its soaring dome. Colorful fishing boats bob in Porto Piccolo while the Ionian Sea provides a sparkling backdrop to centuries of Mediterranean heritage. Traditional Sicilian trattorias serve fresh seafood along the waterfront promenade. Stone-walled boutique guesthouses and converted palazzo B&Bs make perfect bases for exploring this walkable historic quarter. The limited public buses mean you'll mostly discover Santa Lucia's treasures on foot, which is exactly how this ancient place should be experienced.

Grottasanta

The Grottasanta neighborhood offers attractions such as Pista Ciclabile Siracusa and Ionian Sea.

Acradina

The Acradina neighborhood offers attractions such as Ionian Sea and Capuchin Quarry.

Top landmarks in Syracuse

A coastal cityscape with buildings along the waterfront, a clear blue sky, and a calm sea.
Photo by Juan Pablo Pantoja

Lungomare di Ortigia

9.4/10 (654 reviews)
Ortigia is home to Lungomare di Ortigia, so why not stop by during your stay in Syracuse.
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Ancient ruins, a sign reading "Tempio di Apollo," and a man observing the site.

Temple of Apollo

8.8/10 (692 reviews)
If you're planning a bit of sightseeing head to Temple of Apollo— just one of the monuments in Ortigia. You can also discover the museums and cathedral in the area— your sightseeing tour starts here.
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Fontane Bianche Beach

8.0/10 (189 reviews)
When the beach is calling your name, you might want to head down to Fontane Bianche Beach, located 8.5 mi (13.7 km) from central Syracuse. Enjoy the sunset by the shore at Gallina Beach, Arenella Beach, and Lungomare Tremoli Beach.
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Greek Theatre of Syracuse

9.2/10 (694 reviews)
If you're planning a bit of sightseeing head to Greek Theatre of Syracuse— just one of the monuments in Neapolis. You could also start your cultural experience by heading over to the cathedral in the area.
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Piazza del Duomo

9.6/10 (551 reviews)
Piazza del Duomo is worth passing through for a few pics when in Ortigia. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.
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Archaeological Park of Neapolis

9.0/10 (485 reviews)
If you're planning a bit of sightseeing head to Archaeological Park of Neapolis— just one of the monuments in Neapolis. You could also start your cultural experience by heading over to the cathedral in the area.
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Cathedral of Syracuse

9.4/10 (813 reviews)
If you're planning a bit of sightseeing head to Cathedral of Syracuse— just one of the monuments in Ortigia. You can also discover the cathedral and museums in the area— your sightseeing tour starts here.
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Pista Ciclabile Siracusa

10.0/10 (4 reviews)
Travelers who enjoy the great outdoors might want to go to Pista Ciclabile Siracusa, located 1 mi (1.6 km) from central Syracuse.
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