4 Star Hotels in Syracuse

October 2026
12
November 2026

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This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

4 Star Hotels in Syracuse

1. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
$192
$223 total
includes taxes & fees
Nov 6 - Nov 7
Algila' Ortigia Charme Hotel

2. Grande Albergo Alfeo

Grande Albergo Alfeo
Santa Lucia
$101
$115 total
includes taxes & fees
Nov 7 - Nov 8
Grande Albergo Alfeo

3. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
Ortigia
$215
$248 total
includes taxes & fees
Nov 5 - Nov 6
Palazzo Artemide - VRetreats, SLH Collection

4. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
Santa Lucia
$108
$124 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Palazzo Cavalieri

5. Grand Hotel Villa Politi

Grand Hotel Villa Politi
Grottasanta
$116
$132 total
includes taxes & fees
Oct 26 - Oct 27
Grand Hotel Villa Politi

6. Charme Hotel Henry's House

Charme Hotel Henry's House
Ortigia
$248
$284 total
includes taxes & fees
Nov 11 - Nov 12
Charme Hotel Henry's House

7. UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA
Grottasanta
$148
$169 total
includes taxes & fees
Oct 25 - Oct 26
UNA Hotels One Siracusa Wellness & SPA

8. Mercure Siracusa Prometeo

Mercure Siracusa Prometeo
Neapolis
$94
$119 total
includes taxes & fees
Nov 4 - Nov 5
Mercure Siracusa Prometeo

9. Hotel Parco delle Fontane

Hotel Parco delle Fontane
Tiche
$114
$130 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Parco delle Fontane

10. Borgo Pantano

Borgo Pantano
Syracuse
$180
$209 total
includes taxes & fees
Oct 13 - Oct 14
Borgo Pantano

11. Life Hotels Kalaonda Resort

Life Hotels Kalaonda Resort
Syracuse
$107
$122 total
includes taxes & fees
Oct 13 - Oct 14
Life Hotels Kalaonda Resort

12. Hotel Villamare

Hotel Villamare
Syracuse
$146
$166 total
includes taxes & fees
Oct 17 - Oct 18
Hotel Villamare

13. Hotel Centrale

Hotel Centrale
Syracuse
$107
$121 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Centrale

14. Addauro Resort

Addauro Resort
Syracuse
$87
$99 total
includes taxes & fees
Oct 19 - Oct 20
Addauro Resort

15. Albatros Hotel

Albatros Hotel
Syracuse
$108
$123 total
includes taxes & fees
Oct 28 - Oct 29
Albatros Hotel

16. Residence Archimede

Residence Archimede
Syracuse
$124
$141 total
includes taxes & fees
Oct 14 - Oct 15
Residence Archimede

17. Eureka Palace Hotel Spa

Eureka Palace Hotel Spa
Syracuse
$89
$102 total
includes taxes & fees
Oct 18 - Oct 19
Eureka Palace Hotel Spa

18. Hotel Relax

Hotel Relax
Epipoli
$137
$157 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Relax

19. Casal Sikelio

Casal Sikelio
Syracuse
$134
$153 total
includes taxes & fees
Oct 14 - Oct 15
Casal Sikelio

20. Hotel Panorama

Hotel Panorama
Neapolis
$91
$100 total
includes taxes & fees
Nov 10 - Nov 11
Hotel Panorama
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Top neighborhoods in Syracuse

Ortigia

Ortigia's ancient limestone streets tell 2,700 years of Mediterranean stories through every weathered stone. Greek temple ruins stand beside a stunning Baroque cathedral, while the 13th-century Castello Maniace guards this tiny island's tip. The mystical Fonte Aretusa freshwater spring creates a papyrus grove right beside the crystal-clear Ionian Sea. Waterfront trattorias serve fresh seafood and Sicilian classics while you watch fishing boats bobbing at sunset. The compact 1km island is best explored on foot through narrow medieval lanes. Historic palazzos converted to boutique hotels offer authentic stays with sea views from wrought-iron balconies.

Neapolis

Step back in time at Syracuse's Neapolis, where ancient Greek and Roman civilizations come alive through remarkable ruins. The Greek Theater carved into limestone hills offers stunning harbor views, while the Roman Amphitheater reveals gladiatorial heritage. Don't miss the Ear of Dionysius cave where whispers magically amplify, or the Paradise Quarry gardens blooming with Mediterranean flora. Getting around requires walking on uneven ancient paths, with limited bus service connecting to Syracuse center. Pack a lunch or visit the small café near the entrance since dining options are minimal. The archaeological park closes at sunset, so plan your visit during daylight hours to fully experience this extraordinary outdoor museum.

Santa Lucia

Santa Lucia delivers an epic history lesson with every step through its honey-colored streets. The ancient neighborhood showcases Greek ruins, the legendary Tomb of Archimedes, and the stunning Church of Santa Lucia alla Badia with its soaring dome. Colorful fishing boats bob in Porto Piccolo while the Ionian Sea provides a sparkling backdrop to centuries of Mediterranean heritage. Traditional Sicilian trattorias serve fresh seafood along the waterfront promenade. Stone-walled boutique guesthouses and converted palazzo B&Bs make perfect bases for exploring this walkable historic quarter. The limited public buses mean you'll mostly discover Santa Lucia's treasures on foot, which is exactly how this ancient place should be experienced.

Grottasanta

The Grottasanta neighborhood offers attractions such as Pista Ciclabile Siracusa and Ionian Sea.

Tiche

Tiche's ancient Greek quarter lets you walk right through history with every step. The Greek Theater carved into limestone hosts summer performances under starlit skies, while the Temple of Apollo frames perfect Mediterranean sunsets. Explore the Archaeological Park of Neapolis with its mysterious Ear of Dionysius cave, known for its perfect acoustics and surrounded by olive groves. Traditional tavernas serve fresh seafood and arancini in family-run establishments with prices that won't break the bank. Historic guesthouses in converted ancient buildings offer authentic stays with Sicilian breakfasts included. Walking remains the primary way to get around, though public buses connect to central Syracuse when your feet need a rest.

Top landmarks in Syracuse

A coastal cityscape with buildings along the waterfront, a clear blue sky, and a calm sea.
Photo by Juan Pablo Pantoja

Lungomare di Ortigia

9.4/10 (654 reviews)
Ortigia is home to Lungomare di Ortigia, so why not stop by during your stay in Syracuse.
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Ancient ruins, a sign reading "Tempio di Apollo," and a man observing the site.

Temple of Apollo

8.8/10 (692 reviews)
If you're planning a bit of sightseeing head to Temple of Apollo— just one of the monuments in Ortigia. You can also discover the museums and cathedral in the area— your sightseeing tour starts here.
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Fontane Bianche Beach

8.0/10 (189 reviews)
When the beach is calling your name, you might want to head down to Fontane Bianche Beach, located 8.5 mi (13.7 km) from central Syracuse. Enjoy the sunset by the shore at Gallina Beach, Arenella Beach, and Lungomare Tremoli Beach.
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Piazza del Duomo

9.6/10 (551 reviews)
Piazza del Duomo is worth passing through for a few pics when in Ortigia. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.
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Greek Theatre of Syracuse

9.2/10 (694 reviews)
If you're planning a bit of sightseeing head to Greek Theatre of Syracuse— just one of the monuments in Neapolis. You could also start your cultural experience by heading over to the cathedral in the area.
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Archaeological Park of Neapolis

9.0/10 (485 reviews)
If you're planning a bit of sightseeing head to Archaeological Park of Neapolis— just one of the monuments in Neapolis. You could also start your cultural experience by heading over to the cathedral in the area.
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Cathedral of Syracuse

9.4/10 (813 reviews)
If you're planning a bit of sightseeing head to Cathedral of Syracuse— just one of the monuments in Ortigia. You can also discover the cathedral and museums in the area— your sightseeing tour starts here.
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Pista Ciclabile Siracusa

10.0/10 (4 reviews)
Travelers who enjoy the great outdoors might want to go to Pista Ciclabile Siracusa, located 1 mi (1.6 km) from central Syracuse.
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