Hotels in Santa Cruz

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Oct 25 - Oct 26

Tomorrow

Oct 26 - Oct 27

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Where to stay in Santa Cruz?

A pool area with a thatched-roof structure, palm trees, and a staircase leading to an upper level.

A hotel room with a bed, a sofa, a wooden coffee table, a lamp, and a picture on the wall.

A spa area with a hot tub, candles, and towels on a wooden table.

A conference room at Hotel Santa Cruz with rows of chairs, a carpeted floor, wooden beams, and chandeliers.

1. Santa Cruz Plaza

Santa Cruz

$119

$119 total

Nov 8 - Nov 9

A modern building with a pool, lounge chairs, and a mountain view.

A bedroom with a large window, a bed, a desk with a chair, and a blue bean bag.

A modern bathroom with a large window, a curved bathtub, and a view of a valley.

A modern hotel room with a large window, a bed, a seating area with chairs, and a small table.

2. Vik Chile

San Vicente

$769

$769 total

Nov 1 - Nov 2

A pool area with two people sitting by the pool, surrounded by wooden barrels and a chair under a white umbrella.

A hot tub in a vineyard setting with a wooden deck and a wooden fence in the background.

A rustic building with a wooden exterior, a covered entrance, and a well-maintained lawn.

A row of red brick buildings with a flat roof, surrounded by lush greenery.

3. Hotel Cava Colchagua

Santa Cruz

$133

$133 total

Nov 15 - Nov 16

A nighttime view of a hotel with multiple illuminated rooms and a swimming pool reflecting the lights.

A spacious living room with two sofas facing a large window overlooking a garden.

A wooden deck with a view of a forest and mountains.

A multi-story hotel with balconies, large windows, and a swimming pool in the foreground.

4. La Perla Hotel

Santa Cruz

$66

$117 total

Nov 21 - Nov 22

A pool area with a table and chairs, surrounded by a tiled deck and a covered patio.

A spacious room with a grand piano, a comfortable armchair, and a dining table with a vase of flowers.

A room with a large glass door leading to an outdoor area, a small table with a lamp, and a decorative plant.

A street lined with brick buildings, some with balconies and potted plants.

5. Hotel Boutique Grand Cru

Santa Cruz

$90

$90 total

Oct 26 - Oct 27

A wooden building with large windows and a covered patio area with chairs and a table.

A room with a piano, a table with books, a candelabra, and a staircase.

A pool area with white metal chairs and tables, surrounded by potted plants and umbrellas.

A hotel with a stone facade, wooden balconies, and a sign that reads "HOTEL VENDIMIO".

6. Hotel Boutique Vendimia Premium

Santa Cruz

$62

$62 total

Oct 26 - Oct 27

A large estate with multiple buildings, a swimming pool, and extensive vineyard fields.

A long dining table set with chairs, a mural with text and a portrait, and a chandelier.

A covered balcony with a view of a swimming pool and vineyard.

A woman walking through a vineyard path with a building in the background.

7. TerraViña

Santa Cruz

$160

$160 total

Oct 26 - Oct 27

A traditional building with a tiled roof, a welcoming sign, and a large glass door.

A cozy bedroom with a large bed, two chairs, a small table, and a chandelier.

A rustic dining area with wooden tables and chairs, large windows, and potted plants.

A traditional house with a tiled roof, a garden with a large pot and a wheelbarrow, and a well-maintained lawn.

8. Hotel Vendimia Parador

Santa Cruz

$49

$49 total

Nov 18 - Nov 19

A modern outdoor pool area with lounge chairs, a covered patio, and a brick pool.

A spacious room with a high wooden ceiling, multiple hanging pendant lights, and two windows.

A bedroom with a bed, pillows, a patterned blanket, and three wall-mounted decorative plates.

A modern building with a tiled roof and large windows, surrounded by a grassy field and trees.

9. Noi Blend Colchagua

Palmilla

$167

$167 total

Oct 27 - Oct 28

A swimming pool with lounge chairs and umbrellas, surrounded by trees.

A garden pathway leading to a house with a wooden exterior and a porch.

A wooden deck with outdoor seating, a small table, and a blue door labeled "SALA MASAJES".

A garden pathway leading to a building with a reception sign.

10. Casa Calfu

Santa Cruz

$80

$80 total

Oct 28 - Oct 29

A modern lounge area with a sectional sofa, a wooden coffee table, and pendant lighting.

A long table set for dining with chairs, under large yellow canopies, against a wooden wall.

A modern bar area with seating, including a leather sofa and two green armchairs, and a wooden coffee table with decorative items.

A modern hotel room with a large bed, a desk, and a window with a city view.

11. Hotel Curicó

Curicó

$72

$72 total

Oct 31 - Nov 1

A hotel named "TIERRA & VINO" with a car parked in front, a well-maintained hedge, and a traditional tiled roof.

A swimming pool with a tiled edge, a grassy area, and a building with a tiled roof and windows.

A bedroom with a bed, a bedside table with a lamp, a window with curtains, and a door.

A dining area with a wooden table and chairs, a ceiling fan, a mounted TV, and a wall-mounted wine rack.

12. Tierra y Vino

Santa Cruz

An outdoor dining area with wooden tables and chairs, surrounded by lush greenery and a glass door leading to a garden.

A garden with a white umbrella, a red chair, and various plants.

A building with a sign reading "Hostal Vida 2000" and a welcome sign.

A cozy interior with a sofa, a round table, and a large window.

13. Hostal Vida 2000

Santa Cruz

$32

$32 total

Oct 26 - Oct 27

A large building with a tiled roof, surrounded by lush greenery and flowering plants.

A cozy living room with a fireplace, wooden furniture, and a chandelier.

A well-maintained garden with a gravel path leading to a building with warm lighting.

A person sitting by a pool with a drink, a glass of water, and a snack tray.

14. Hotel Viña La Playa

Peralillo

$212

$212 total

Oct 29 - Oct 30

The exterior of Hotel Diego de Almagro with a prominent entrance, large columns, and a modern facade.

A restaurant with a central counter, multiple tables with chairs, and a bar area.

An indoor swimming pool with a skylight, lounge chairs, and a lifebuoy.

A hotel room with a large bed, a desk, a chair, a TV, and a wardrobe.

15. Hotel Diego de Almagro Curico

Curicó

A modern bathroom with a freestanding bathtub, a wine glass, and candles.

A modern, well-lit building with a glass facade, a wooden deck with lounge chairs, and a hanging light fixture.

A modern bedroom with a large window, a bed, a small table, and a chair.

A sign for 'RECEPCIÓN V130' at a wine lodge.

16. Vibo Wine Lodge

Santa Cruz

A wooden building with outdoor seating and a covered patio area.

A hotel entrance with a purple mat, wicker chairs, and potted plants.

A yellow building with a tiled roof and a covered porch.

An outdoor seating area with wicker furniture and a lantern.

17. Hotel Ontiveros

San Fernando

$64

$64 total

Oct 27 - Oct 28

A neatly made bed with a striped bedspread and two pillows, a framed picture on the wall, and a window with curtains.

A pool area with lounge chairs and a pergola.

A dirt path flanked by tall palm trees in a lush, green environment.

A four-poster bed with a bench, a nightstand, a chair, and a window with curtains.

18. Hacienda Histórica Marchigüe

Marchihue

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A wooden building with large windows and a covered patio area with chairs and a table.

A room with a piano, a table with books, a candelabra, and a staircase.

A pool area with white metal chairs and tables, surrounded by potted plants and umbrellas.

A hotel with a stone facade, wooden balconies, and a sign that reads "HOTEL VENDIMIO".

Hotel Boutique Vendimia Premium

Santa Cruz

$62

per night

$62 total

A pool area with a thatched-roof structure, palm trees, and a staircase leading to an upper level.

A hotel room with a bed, a sofa, a wooden coffee table, a lamp, and a picture on the wall.

A spa area with a hot tub, candles, and towels on a wooden table.

A conference room at Hotel Santa Cruz with rows of chairs, a carpeted floor, wooden beams, and chandeliers.

Santa Cruz Plaza

Santa Cruz

$134

per night

$134 total

A traditional building with a tiled roof, a welcoming sign, and a large glass door.

A cozy bedroom with a large bed, two chairs, a small table, and a chandelier.

A rustic dining area with wooden tables and chairs, large windows, and potted plants.

A traditional house with a tiled roof, a garden with a large pot and a wheelbarrow, and a well-maintained lawn.

Hotel Vendimia Parador

Santa Cruz

$49

per night

$49 total

A pool area with two people sitting by the pool, surrounded by wooden barrels and a chair under a white umbrella.

A hot tub in a vineyard setting with a wooden deck and a wooden fence in the background.

A rustic building with a wooden exterior, a covered entrance, and a well-maintained lawn.

A row of red brick buildings with a flat roof, surrounded by lush greenery.

Hotel Cava Colchagua

Santa Cruz

$18 off

$165

per night

$165 total

A swimming pool with lounge chairs and umbrellas, surrounded by trees.

A garden pathway leading to a house with a wooden exterior and a porch.

A wooden deck with outdoor seating, a small table, and a blue door labeled "SALA MASAJES".

A garden pathway leading to a building with a reception sign.

Casa Calfu

Santa Cruz

$9 off

$81

per night

$81 total

A cozy room with a bed, a table, and a view of the outdoors through a triangular window.

A wooden shelf with towels hanging on hooks, labeled "Colchagui Tiny Lodge."

A wooden cabin with a curved roof and large windows, situated on a wooden deck in a lush, green landscape.

A rustic cabin with a wooden deck, surrounded by lush greenery and a mountainous backdrop.

Colchagua Tiny Lodge

Santa Cruz

$20 off

$181

per night

$181 total

You can also stay at hotels with a pool in Santa Cruz

A pool area with a thatched-roof structure, palm trees, and a staircase leading to an upper level.

A hotel room with a bed, a sofa, a wooden coffee table, a lamp, and a picture on the wall.

A spa area with a hot tub, candles, and towels on a wooden table.

A conference room at Hotel Santa Cruz with rows of chairs, a carpeted floor, wooden beams, and chandeliers.

Santa Cruz Plaza

Santa Cruz

$119

$119 total

Nov 8 - Nov 9

A large estate with multiple buildings, a swimming pool, and extensive vineyard fields.

A long dining table set with chairs, a mural with text and a portrait, and a chandelier.

A covered balcony with a view of a swimming pool and vineyard.

A woman walking through a vineyard path with a building in the background.

TerraViña

Santa Cruz

$160

$160 total

Oct 26 - Oct 27

A wooden building with large windows and a covered patio area with chairs and a table.

A room with a piano, a table with books, a candelabra, and a staircase.

A pool area with white metal chairs and tables, surrounded by potted plants and umbrellas.

A hotel with a stone facade, wooden balconies, and a sign that reads "HOTEL VENDIMIO".

Hotel Boutique Vendimia Premium

Santa Cruz

$62

$62 total

Oct 26 - Oct 27

A pool area with two people sitting by the pool, surrounded by wooden barrels and a chair under a white umbrella.

A hot tub in a vineyard setting with a wooden deck and a wooden fence in the background.

A rustic building with a wooden exterior, a covered entrance, and a well-maintained lawn.

A row of red brick buildings with a flat roof, surrounded by lush greenery.

Hotel Cava Colchagua

Santa Cruz

$133

$133 total

Nov 15 - Nov 16

A traditional building with a tiled roof, a welcoming sign, and a large glass door.

A cozy bedroom with a large bed, two chairs, a small table, and a chandelier.

A rustic dining area with wooden tables and chairs, large windows, and potted plants.

A traditional house with a tiled roof, a garden with a large pot and a wheelbarrow, and a well-maintained lawn.

Hotel Vendimia Parador

Santa Cruz

$49

$49 total

Nov 18 - Nov 19

A pool area with a table and chairs, surrounded by a tiled deck and a covered patio.

A spacious room with a grand piano, a comfortable armchair, and a dining table with a vase of flowers.

A room with a large glass door leading to an outdoor area, a small table with a lamp, and a decorative plant.

A street lined with brick buildings, some with balconies and potted plants.

Hotel Boutique Grand Cru

Santa Cruz

$90

$90 total

Oct 26 - Oct 27

A swimming pool with lounge chairs and umbrellas, surrounded by trees.

A garden pathway leading to a house with a wooden exterior and a porch.

A wooden deck with outdoor seating, a small table, and a blue door labeled "SALA MASAJES".

A garden pathway leading to a building with a reception sign.

Casa Calfu

Santa Cruz

$80

$80 total

Oct 28 - Oct 29

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Go beyond your typical stay in Santa Cruz

Pool

Spa

Family friendly

Our prices for hotels in Santa Cruz are cheapest in April

Top landmarks in Santa Cruz

Lapostolle Clos Apalta Winery

9.4/10 (21 reviews)

Travelers might want a tour of Lapostolle Clos Apalta Winery, just one of the places to visit, and located 5.3 mi (8.5 km) from central Santa Cruz.

Casino Colchagua

8.0/10 (6 reviews)

Casino Colchagua is 1.4 mi (2.2 km) from central Santa Cruz, why not stop by during your stay.

Colchagua Campo y Vino

9.4/10 (3 reviews)

Colchagua Campo y Vino is 1.4 mi (2.2 km) from central Santa Cruz, why not stop by during your stay.

Laura Hartwig Winery

9.0/10 (17 reviews)

Travelers might want a tour of Laura Hartwig Winery, just one of the places to visit, and located 0.8 mi (1.3 km) from central Santa Cruz.

Bodega Viña Viu Manent

10.0/10 (1 review)

Travelers might want a tour of Bodega Viña Viu Manent, just one of the places to visit, and located 3.4 mi (5.4 km) from central Santa Cruz.

Plaza de Armas

8.2/10 (34 reviews)

If you're planning a bit of sightseeing during your trip, head to Plaza de Armas— just one of the monuments in central Santa Cruz.

Museo de Colchagua

9.6/10 (24 reviews)

The center of Santa Cruz is home to cultural attractions like Museo de Colchagua, so you might want to stop by during your stay. If you want to experience more of the culture Santa Cruz has to offer, head to Casino Colchagua, Laura Hartwig Winery, and Colchagua Campo y Vino.

Learn more about Santa Cruz

Notable for its wineries, Santa Cruz features attractions such as Casino Colchagua and Colchagua Campo y Vino. This relaxing city has something for everyone including restaurants as well as sights like Lapostolle Clos Apalta Winery and Millahue Valley. All are within a rural setting.

See all hotels in Santa Cruz

A vineyard with rows of grapevines, terraced fields, and mountains in the background.

Check out reviews of Santa Cruz hotels guests love

Hotel Vendimia Parador

Hotel Vendimia Parador

10/10 Excellent

"Our stay was wonderful. The property was surrounded with beautiful sights from fascinating antiques to the lush gardens. The owners were very attentive and always available for whatever we needed or had questions about. The breakfast was delicious and elegant. Cannot say enough about our stay. Everything was perfect. It was located very close to a few dining options and wineries too!"

Santa Cruz Plaza

Santa Cruz Plaza

8/10 Good

"El hotel ya está muy viejo, tiene buenas instalaciones y el spa está bien pero las habitaciones ocupan renovación, sobre todo alfombras y aire acondicionado."

TerraViña

TerraViña

10/10 Excellent

"The staff were very friendly and knowledgeable of the local restaurants and wineries. The room has a balcony which was fabulous. Properly was well maintained and beautiful. Definitely would come back to this property."

Hotel Cava Colchagua

Hotel Cava Colchagua

10/10 Excellent

"Excelente y original experiencia boutique Una propuesta realmente innovadora. Se trata de un hotel boutique hermoso cuyas habitaciones están acondicionadas dentro de barricas de roble, muy bien adaptadas y acogedoras. Como sugerencia de mejora, creo que a las habitaciones más grandes les vendría muy bien incluir un perchero y una pequeña mesa con dos sillas para mayor comodidad. Asimismo, en el baño eché de menos una mejor iluminación en el área del espejo. Por lo demás, todo fenomenal. El personal es sumamente amable y siempre está atento a cualquier necesidad. ¡Regresaría sin dudarlo!"

Hotel Boutique Grand Cru

Hotel Boutique Grand Cru

10/10 Excellent

"Great breakfast. Super host Juan Luis. Great location. Comfy bed. Spacious loft style rooms "

Frequently asked questions

What accommodations do travelers recommend in Santa Cruz?

Guests like Santa Cruz Plaza, Hotel Cava Colchagua and La Perla Hotel.

Where can I find free parking at my hotel in Santa Cruz?

These hotels offer the perk of free parking: Tierra y Vino, Hostal Gomero and Whay Hau.

Can I book refundable accommodations in Santa Cruz?

If you need the flexibility to change your plans to Santa Cruz, most properties offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Santa Cruz be like during my visit?

January and February are typically the warmest months in Santa Cruz when the average temp is 70°F. July and August are the coldest months when the average temperature is 50°F. June and August are the months with the most rain.

Why should I book my Santa Cruz hotel through Hotels.com?

There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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