Hotels in Seneca

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Tonight
Aug 6 - Aug 7
Tomorrow
Aug 7 - Aug 8
This weekend
Aug 7 - Aug 9
Next weekend
Aug 14 - Aug 16

Where to stay in Seneca?

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
$100
$110 total
includes taxes & fees
Aug 23 - Aug 24
Tru by Hilton Seneca Clemson

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$76
$93 total
includes taxes & fees
Aug 16 - Aug 17
Quality Inn Seneca US-123

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
$120
$131 total
includes taxes & fees
Aug 20 - Aug 21
Hampton Inn & Suites Seneca-Clemson Area

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
$101
$111 total
includes taxes & fees
Aug 16 - Aug 17
Best Western Seneca-Clemson

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
$109
$135 total
includes taxes & fees
Aug 9 - Aug 10
Lakeside Lodge Clemson

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$71
$79 total
includes taxes & fees
Aug 16 - Aug 17
Days Inn by Wyndham Seneca / Clemson Area

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
$129
$142 total
includes taxes & fees
Aug 23 - Aug 24
Fairfield Inn & Suites Seneca Clemson Univ Area

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
$99
$153 total
includes taxes & fees
Aug 17 - Aug 18
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
Clemson
$149
$165 total
includes taxes & fees
Sep 1 - Sep 2
Clemson University's James F. Martin Inn

Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
Clemson
$102
$113 total
includes taxes & fees
Aug 16 - Aug 17
Hampton Inn Clemson-University Area

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
Clemson
$99
$110 total
includes taxes & fees
Aug 16 - Aug 17
Comfort Inn & Suites Clemson - University Area

The Abernathy of Clemson

The Abernathy of Clemson
Clemson
$152
$169 total
includes taxes & fees
Aug 30 - Aug 31
The Abernathy of Clemson

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
Clemson
$105
$117 total
includes taxes & fees
Aug 16 - Aug 17
Best Western Plus Clemson Hotel & Conference Center

Inn @ Clemson

Inn @ Clemson
Clemson
$99
$110 total
includes taxes & fees
Aug 9 - Aug 10
Inn @ Clemson

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
Walhalla
$76
$85 total
includes taxes & fees
Aug 16 - Aug 17
Rodeway Inn & Suites Walhalla

The Point At Lake Hartwell

The Point At Lake Hartwell
Townville
$125
$139 total
includes taxes & fees
Aug 7 - Aug 8
The Point At Lake Hartwell

Courtyard Marriott Clemson

Courtyard Marriott Clemson
Clemson
$110
$122 total
includes taxes & fees
Sep 1 - Sep 2
Courtyard Marriott Clemson

Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
Clemson
$110
$122 total
includes taxes & fees
Aug 16 - Aug 17
Holiday Inn Express & Suites Clemson by IHG

The Inn at Patrick Square

The Inn at Patrick Square
Clemson
$149
$165 total
includes taxes & fees
Aug 23 - Aug 24
The Inn at Patrick Square

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
$239
$265 total
includes taxes & fees
Aug 19 - Aug 20
The Shepherd Hotel Downtown Clemson
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Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$94
per night
$114 total
includes taxes & fees
Quality Inn Seneca US-123

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
$120
per night
$132 total
includes taxes & fees
Best Western Seneca-Clemson

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$10 off
$90
per night
$99 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
$159
per night
$175 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
$169
per night
$186 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
$189
per night
$208 total
includes taxes & fees
Tru by Hilton Seneca Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
$179
per night
$241 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$150
per night
$354 total
includes taxes & fees
Quality Inn Seneca US-123

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$48 off
$136
per night
$300 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
$238
per night
$525 total
includes taxes & fees
Best Western Seneca-Clemson

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
$322
per night
$707 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area

6 Mi to South Cove Boat Ramp! Lake Keowee Escape

6 Mi to South Cove Boat Ramp! Lake Keowee Escape
Seneca
$248
per night
$777 total
includes taxes & fees
6 Mi to South Cove Boat Ramp! Lake Keowee Escape

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
$239
per night
$614 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
$380
per night
$837 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area

Lakefront Getaway Dock Fire Pit Kayak Games

Lakefront Getaway Dock Fire Pit Kayak Games
Seneca
$184 off
$826
per night
$2,231 total
includes taxes & fees
Lakefront Getaway Dock Fire Pit Kayak Games

8 Mi to Clemson: Peaceful Family Home w/ Yard

8 Mi to Clemson: Peaceful Family Home w/ Yard
Seneca
$187
per night
$613 total
includes taxes & fees
8 Mi to Clemson: Peaceful Family Home w/ Yard

Home 11 Mi to Clemson: Lake-view Balcony & Dock!

Home 11 Mi to Clemson: Lake-view Balcony & Dock!
Seneca
$273
per night
$802 total
includes taxes & fees
Home 11 Mi to Clemson: Lake-view Balcony & Dock!

Lake Keowee Gem! Close to Clemson & Hiking Trails

Lake Keowee Gem! Close to Clemson & Hiking Trails
Seneca
$429
per night
$1,205 total
includes taxes & fees
Lake Keowee Gem! Close to Clemson & Hiking Trails

Boating & Fishing Basecamp! Lake Keowee Hideaway

Boating & Fishing Basecamp! Lake Keowee Hideaway
Seneca
$395
per night
$1,219 total
includes taxes & fees
Boating & Fishing Basecamp! Lake Keowee Hideaway

Check out hotels with a pool in Seneca

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
$101
$111 total
includes taxes & fees
Aug 16 - Aug 17
Best Western Seneca-Clemson

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
$109
$135 total
includes taxes & fees
Aug 9 - Aug 10
Lakeside Lodge Clemson

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$76
$93 total
includes taxes & fees
Aug 16 - Aug 17
Quality Inn Seneca US-123

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
$120
$131 total
includes taxes & fees
Aug 20 - Aug 21
Hampton Inn & Suites Seneca-Clemson Area

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
$129
$142 total
includes taxes & fees
Aug 23 - Aug 24
Fairfield Inn & Suites Seneca Clemson Univ Area

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$71
$79 total
includes taxes & fees
Aug 16 - Aug 17
Days Inn by Wyndham Seneca / Clemson Area
View all properties

You may also like pet-friendly hotels in Seneca

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
$100
$110 total
includes taxes & fees
Aug 23 - Aug 24
Tru by Hilton Seneca Clemson

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
$76
$93 total
includes taxes & fees
Aug 16 - Aug 17
Quality Inn Seneca US-123

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
$71
$79 total
includes taxes & fees
Aug 16 - Aug 17
Days Inn by Wyndham Seneca / Clemson Area

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
$109
$135 total
includes taxes & fees
Aug 9 - Aug 10
Lakeside Lodge Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
$99
$153 total
includes taxes & fees
Aug 17 - Aug 18
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Seneca are cheapest in December
Price trends for hotels in Seneca
Pricing is based on two traveler single night rates
View properties in August
Typical weather for Seneca
August
High 31°C / low 20°C. Sunny most days.
View properties in August
31°
20°
28°
18°
23°
12°
17°
12°
10°
13°
17°
22°
10°
26°
15°
31°
19°
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21°
Monthly weather averages (˚C)

Top neighborhoods in Seneca

Downtown

Downtown Seneca charms visitors with well-preserved historical buildings that tell the story of its railroad heritage. The tree-lined Ram Cat Alley showcases local history through colorful murals, while the old courthouse square hosts seasonal farmers markets and community events. You can explore the Bertha Lee Strickland Cultural Museum or browse antique shops filled with Southern treasures. Family-owned cafes serve up delicious Southern comfort food like fried green tomatoes and barbecue. Accommodations range from historic bed & breakfasts in Victorian homes to budget-friendly motels. The entire downtown is walkable with wide sidewalks, making it easy to discover this authentic slice of small-town America at your own pace.

Serenity Bay

Lake Keowee beckons from this peaceful coastal retreat nestled in Saxony Forest. Serenity Bay lives up to its name with tree-lined streets perfect for contemplative walks. Nearby Keowee Key Golf Course offers tee times for enthusiasts, while South Beach provides sandy relaxation without the crowds. The natural setting creates an ideal escape for bird watchers and nature photographers. Vacation rentals with weathered wood siding and muted earth tones blend seamlessly into the forest canopy. Getting around requires your own wheels since public transit is limited. The neighborhood trades bustling nightlife for cricket choruses and ocean breezes filtering through pine trees—exactly what makes this hidden gem worth finding.

Pine Ridge Point

Lake Keowee sparkles as the crown jewel of Pine Ridge Point, a peaceful residential haven in Seneca. Waterfront vacation homes nestle among tall pines, offering private docks and stunning views. Visitors spend days swimming in crystal-clear waters, boating across the lake, or simply unwinding on expansive decks beneath Carolina blue skies. This neighborhood is all about authentic lakeside living without commercial distractions. Most travelers cook in well-equipped rental kitchens or drive 15 minutes to Seneca for restaurants. Personal vehicles are essential for getting around, though scenic paths along the shoreline make for perfect evening strolls.

Indian Oaks

Indian Oaks gives you all the peaceful vibes of suburban life with none of the tourist chaos. This leafy neighborhood in Seneca lets you live like a local under a canopy of mature oak trees. The curved streets and manicured lawns create a park-like setting that's perfect for morning walks. Lake Keowee is just a short drive away when you need a water fix. You'll need wheels to get around since public transit is limited and restaurants aren't within walking distance. Most visitors stay in vacation rental homes with private yards and driveways. The neighborhood gets incredibly quiet after dark—ideal for travelers who want to experience authentic suburban living while having Seneca's attractions nearby.

Top landmarks in Seneca

A grassy field with yellow flowers and trees in the foreground, with mountains in the background.

Blue Ridge Field

Blue Ridge Field is worth a visit, located 0.8 mi (1.2 km) from central Seneca.
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A waterfall surrounded by autumn foliage.

High Falls County Park

High Falls County Park is worth a visit, located 7.8 mi (12.5 km) from central Seneca.
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Friendship Recreation Area

Friendship Recreation Area is worth a visit, located 6.5 mi (10.5 km) from central Seneca.
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Oconee County Library Seneca Branch

Oconee County Library Seneca Branch is worth a pic or two when discovering Downtown.
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Highpointe Field

Highpointe Field is worth a visit, located 5.6 mi (8.9 km) from central Seneca.
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South Cove Park

South Cove Park is worth a visit, located 2 mi (3.3 km) from central Seneca.
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The Gauntlet

If you want to see a show while you're in town, try and grab some tickets at The Gauntlet in Downtown. If you enjoy the show and want to see another, Oconee Community Theatre isn't far.
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Seneca Historic District

If you're planning a bit of sightseeing head to Seneca Historic District— just one of the monuments in Downtown.
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Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic downtown offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

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A calm lake with mountains in the background.

Check out reviews of Seneca hotels guests love

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

8/10 Good
"It was a good getaway trip"
laysha 2-night trip
Posted 4 days ago
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

10/10 Excellent
"Room was fine"
Cory 1-night trip
Posted 4 days ago
Fairfield Inn & Suites Seneca Clemson Univ Area
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

10/10 Excellent
"Rooms were clean pool was clean staff was very accommodating room stayed nice and cool. LOTS of store and food options close by, walking distance."
Talisha 1-night trip
Posted 9 days ago
Days Inn by Wyndham Seneca / Clemson Area

Frequently asked questions

What accommodations do travelers like in Seneca?
Can I book refundable accommodations in Seneca?
If you want the flexibility to change your travel plans to Seneca, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a budget-friendly accommodation?
Lakeside Lodge Clemson, Tru by Hilton Seneca Clemson and Quality Inn Seneca US-123 are a few accommodations you might want to consider that'll save you money.
Where can I stay in Seneca if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 212 vacation homes. In addition, there are 21 apartments and 12 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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