Hotels in Santee

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Check prices for these dates

Next weekend
May 22 - May 24
In two weeks
May 29 - May 31

Where to stay in Santee?

Free daily buffet breakfast

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (828 reviews)
Bright, modern hotel near Santee National Golf Club with a refreshing indoor pool for year-round swimming. Guests love the complimentary breakfast, 24-hour fitness center, and helpful staff. Free WiFi and parking add convenience to your Santee visit.
The price is $106
$118 total
includes taxes & fees
May 27 - May 28
Tru By Hilton Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,463 reviews)
Escape to this quiet Santee hotel where comfortable beds await after exploring local golf clubs. Free perks include daily continental breakfast, WiFi, and parking. Guests praise the convenient location close to everything they need.
The price is $75
$83 total
includes taxes & fees
May 17 - May 18
Baymont by Wyndham Santee
Exterior

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,002 reviews)
The price is $118
$131 total
includes taxes & fees
May 25 - May 26
Best Western Plus Santee Inn
Property amenity

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,002 reviews)
Guests love this quiet Santee hotel for its helpful staff and complimentary breakfast. The outdoor pool and health club offer refreshing workout options, while free parking and WiFi add convenience. Golf enthusiasts will appreciate the nearby Santee Cooper Country Club.
The price is $139
$154 total
includes taxes & fees
Jun 1 - Jun 2
Fairfield Inn & Suites by Marriott Santee
Free breakfast

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,003 reviews)
The price is $119
$132 total
includes taxes & fees
May 25 - May 26
Hampton Inn Santee-I-95
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,001 reviews)
This peaceful hotel in Santee's entertainment district offers a quiet retreat with free breakfast and parking. Located near Santee Cooper Country Club, guests can enjoy the fitness center or take a refreshing dip in the seasonal pool. The staff earns consistent praise for their helpfulness.
The price is $114
$126 total
includes taxes & fees
May 25 - May 26
Comfort Inn & Suites Santee
Point of interest

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,001 reviews)
Swing into action at this golf-adjacent hotel featuring an indoor pool and 24-hour fitness center. Relax on the terrace or enjoy a drink at the bar after playing nearby Santee Cooper Country Club. Clean rooms with refrigerators and microwaves create a comfortable home base.
The price is $122
$135 total
includes taxes & fees
May 25 - May 26
Holiday Inn Santee by IHG
Free daily full breakfast

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (528 reviews)
Wake up to free breakfast at this convenient Santee hotel with 7 dining options and a seasonal outdoor pool. After exploring nearby Santee Cooper Country Club, unwind at the bar. Clean rooms, helpful staff, and free WiFi and parking enhance your stay.
The price is $54
$66 total
includes taxes & fees
Jun 7 - Jun 8
Quality Inn & Suites Santee I-95
In-room safe, iron/ironing board, free WiFi, bed sheets

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (731 reviews)
The price is $63
$70 total
includes taxes & fees
May 26 - May 27
Travelodge by Wyndham Santee
Exterior

Super 8 by Wyndham Santee

Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (461 reviews)
Overlooking a golf course, this tranquil motel offers a refreshing seasonal outdoor pool and complimentary breakfast served daily. Located near Santee Cooper Country Club, guests enjoy free WiFi and parking during their stay.
The price is $64
$71 total
includes taxes & fees
May 24 - May 25
Super 8 by Wyndham Santee
Exterior

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (654 reviews)
Minutes from Santee Cooper Country Club, this welcoming hotel offers free WiFi, parking, and daily continental breakfast. Adventure seekers will appreciate the nearby water skiing opportunities, while golf enthusiasts can enjoy Santee National Golf Club just a short drive away.
The price is $63
$70 total
includes taxes & fees
May 20 - May 21
Red Roof Inn Santee
Lobby

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (558 reviews)
Steps from Santee Cooper Country Club, this hotel offers rooms with refrigerators and microwaves. After a round of golf, enjoy the poolside bar and on-site restaurant. Free WiFi and parking make exploring nearby attractions easy.
The price is $72
$80 total
includes taxes & fees
May 24 - May 25
Ramada by Wyndham Santee I-95
Desk, iron/ironing board, free WiFi, bed sheets

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (314 reviews)
Located near Santee Cooper Country Club, this hotel offers free WiFi and parking. You'll appreciate the 24-hour front desk service while exploring nearby attractions including Santee National Golf Club.
The price is $76
$84 total
includes taxes & fees
May 31 - Jun 1
Econo Lodge Santee
Panoramic Tent | Lake view

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (93 reviews)
Escape to this waterfront resort with its own marina and restaurant. Just minutes from Ferguson Island, you'll appreciate the fitness center, helpful staff, and complimentary WiFi. Nearby Round Island provides additional exploration opportunities.
The price is $118
$134 total
includes taxes & fees
May 17 - May 18
Bells Marina & Resort
Front of property

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.4 out of 10, Good, (206 reviews)
The price is $51
$55 total
includes taxes & fees
May 24 - May 25
Peach Tree Inn
Outdoor dining

Doyles B and B at Players course LLC

Doyles B and B at Players course LLC
3.5 star property
Manning
The price is $135
$150 total
includes taxes & fees
May 17 - May 18
Doyles B and B at Players course LLC
Lobby

Sunset Inn Manning I 95

Sunset Inn Manning I 95
2.0 star property
Summerton
4.8 out of 10, (55 reviews)
The price is $54
$60 total
includes taxes & fees
Jun 15 - Jun 16
Sunset Inn Manning I 95
Front of property

Starlight Stays

Starlight Stays
2.5 star property
Manning
7.8 out of 10, Good, (16 reviews)
This comfortable hotel offers peaceful accommodation with in-room coffeemakers and daily housekeeping services. Just a short drive from Florence Regional Airport and popular Wyboo Golf Club, Starlight Stays provides a convenient base for exploring Manning.
The price is $66
$73 total
includes taxes & fees
May 17 - May 18
Starlight Stays
Lobby

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (767 reviews)
Near Smith-Hammond-Middleton Memorial Center, this business-friendly hotel offers free breakfast, WiFi, and parking. Take a refreshing dip in the seasonal outdoor pool or visit the fitness center. Clean rooms and helpful staff create a welcoming atmosphere.
The price is $110
$122 total
includes taxes & fees
May 17 - May 18
Fairfield Inn by Marriott Orangeburg
Deluxe Room, 1 King Bed, Non Smoking | Iron/ironing board, free WiFi, bed sheets

Baymont by Wyndham Manning

Baymont by Wyndham Manning
2.5 star property
Manning
7.0 out of 10, Good, (1,001 reviews)
Unwind in comfort at this Manning hotel, offering a complimentary continental breakfast to start your day. Clean rooms provide a peaceful retreat, while free WiFi keeps you connected. The helpful staff ensures a pleasant stay, with convenient free parking included.
The price is $80
$89 total
includes taxes & fees
May 17 - May 18
Baymont by Wyndham Manning
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Showing deals for:May 16 - May 17
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,463 reviews)
The price is $130
per night
$144 total
includes taxes & fees
Baymont by Wyndham Santee
Showing deals for:May 17 - May 18
Exterior
Best Western Plus Santee Inn

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,002 reviews)
The price is $140
per night
$155 total
includes taxes & fees
Best Western Plus Santee Inn
Showing deals for:May 22 - May 24
Exterior
Best Western Plus Santee Inn

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,002 reviews)
The price is $169
per night
$375 total
includes taxes & fees
Best Western Plus Santee Inn

Check out pet-friendly hotels in Santee

Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1463)
The price is $75
$83 total
includes taxes & fees
May 17 - May 18
Baymont by Wyndham Santee
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You may also like hotels with pools in Santee

Free daily buffet breakfast
Tru By Hilton Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (828)
The price is $106
$118 total
includes taxes & fees
May 27 - May 28
Tru By Hilton Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit Santee?

Our prices for hotels in Santee are cheapest in December
Price trends for hotels in Santee
Pricing is based on two traveler single night rates
View properties in May
Currently viewing crowd sizes and weather for May.
Typical weather for Santee
May
High 28°C / low 17°C. Sunny most days.
View properties in May
28°
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May, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
31°
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June, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
33°
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July, no crowd data, average high temperature 33 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
32°
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August, no crowd data, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
29°
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September, no crowd data, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
24°
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October, no crowd data, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
19°
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November, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
15°
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December, no crowd data, average high temperature 15 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
7°
13°
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January, no crowd data, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
4°
16°
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February, no crowd data, average high temperature 16 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
6°
19°
weather_sun
March, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
24°
weather_sun
April, no crowd data, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
Monthly weather averages (˚C)

Top landmarks in Santee

Santee State Park

4.0/5 (219 reviews)
Santee State Park is 2.7 mi (4.4 km) from central Santee, why not stop by during your stay.
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Learn more about Santee

Tee off at championship golf courses or cast a line in Lake Marion's fish-rich waters where locals claim the bass practically jump into your boat. The Santee National Wildlife Refuge offers hiking trails where alligators sun themselves with reptilian nonchalance. Interstate 95 crosses the lake on a causeway that provides views worth pulling over for (safely, of course). Santee State Park delivers lakeside tranquility that makes visitors forget their phones exist. This resort town punches well above its weight with dining options that range from fresh-caught catfish to surprisingly sophisticated fare. The recent addition of the Santee Cooper Regional Water System has locals buzzing about growth while still cherishing their small-town atmosphere.

See all hotels in Santee
Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Check out reviews of Santee hotels guests love

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"."
Keith 1-night trip
Posted 2 hours ago
Hampton Inn Santee-I-95

Frequently asked questions

What accommodations do travelers like in Santee?
Guests like Baymont by Wyndham Santee, Tru By Hilton Santee and Comfort Inn & Suites Santee.
Can I book refundable accommodations in Santee?
If you want the flexibility to change your plans to Santee, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where should I stay in Santee if I'm looking for a reasonably priced accommodation?
A few inexpensive options worth considering are Baymont by Wyndham Santee, Tru By Hilton Santee and Comfort Inn & Suites Santee.
Where can I stay in Santee if I want a vacation rental instead of a hotel?
Browse 8 vacation homes on our site. You also might want to book one of 98 condos for your trip.
What will the weather in Santee be like during my vacation?
July and August are typically the warmest months in Santee when the average temp is 79°F. January and February are the coldest months when the average temperature is 52°F. August and July are the months with the most rain.
Why should I book my Santee hotel with Hotels.com?
There are lots of reasons to book your Santee trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.