Hotels in Santee

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Check prices for these dates

Tonight
Mar 24 - Mar 25
Tomorrow
Mar 25 - Mar 26
This weekend
Mar 27 - Mar 29
Next weekend
Apr 3 - Apr 5

Where to stay in Santee?

Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 star property
Santee
7.8 out of 10, Good, (1,425 reviews)
  • cleanliness
    Relax in peaceful Santee with continental breakfast and helpful staff nearby.
The price is $80
$89 total
includes taxes & fees
Mar 25 - Mar 26
Baymont by Wyndham Santee
In-room safe, iron/ironing board, free WiFi, bed sheets
Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2.0 star property
Santee
7.0 out of 10, Good, (710 reviews)
The price is $63
$70 total
includes taxes & fees
Mar 25 - Mar 26
Travelodge by Wyndham Santee
Exterior
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,006 reviews)
The price is $119
$132 total
includes taxes & fees
Mar 30 - Mar 31
Best Western Plus Santee Inn
Free daily buffet breakfast
Tru By Hilton Santee
Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (769 reviews)
  • cleanliness
    Experience a comfortable stay near Santee Cooper Country Club with top-rated service.
The price is $119
$132 total
includes taxes & fees
Apr 13 - Apr 14
Tru By Hilton Santee
Free daily full breakfast
Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (489 reviews)
  • cleanliness
    Experience the gateway to Santee's acclaimed golf clubs with complimentary perks.
The price is $54
$66 total
includes taxes & fees
Mar 30 - Mar 31
Quality Inn & Suites Santee I-95
Exterior
Red Roof Inn Santee
Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (646 reviews)
  • cleanliness
    Stay active in Santee with water skiing near this friendly hotel with free perks.
The price is $58
$65 total
includes taxes & fees
Mar 30 - Mar 31
Red Roof Inn Santee
Lobby
Super 8 by Wyndham Santee
Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (446 reviews)
  • cleanliness
    Enjoy a peaceful golf escape at this quiet Santee motel with seasonal pool.
The price is $75
$83 total
includes taxes & fees
Mar 25 - Mar 26
Super 8 by Wyndham Santee
Property amenity
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,003 reviews)
  • cleanliness
    Comfortable hotel in a tranquil setting, perfect for morning swims and golf outings.
The price is $143
$159 total
includes taxes & fees
Apr 5 - Apr 6
Fairfield Inn & Suites by Marriott Santee
Exterior
Holiday Inn Santee by IHG
Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Golfer's getaway with lakeside views and modern comforts in charming Santee.
The price is $136
$151 total
includes taxes & fees
Mar 29 - Mar 30
Holiday Inn Santee by IHG
Free breakfast
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,003 reviews)
The price is $135
$150 total
includes taxes & fees
Apr 5 - Apr 6
Hampton Inn Santee-I-95
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,005 reviews)
  • cleanliness
    Relax in a serene hotel with a seasonal outdoor pool near Santee attractions.
The price is $121
$134 total
includes taxes & fees
Mar 30 - Mar 31
Comfort Inn & Suites Santee
Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Santee
Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (312 reviews)
  • cleanliness
    Unwind in Santee with easy golf club access and no-cost essentials.
The price is $68
$76 total
includes taxes & fees
Apr 7 - Apr 8
Econo Lodge Santee
Desk, laptop workspace, iron/ironing board, free WiFi
SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1,005 reviews)
  • cleanliness
    Just minutes from I-95, this hotel offers clean, comfortable accommodations.
The price is $95
$105 total
includes taxes & fees
Mar 30 - Mar 31
SureStay Hotel by Best Western Manning
Restaurant
Hampton Inn Manning
Hampton Inn Manning
2.5 star property
Manning
8.4 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Comfortable South Carolina lodgings near I-95 with 24-hour fitness center.
The price is $143
$159 total
includes taxes & fees
Apr 19 - Apr 20
Hampton Inn Manning
Standard Room Double Bed | Desk, free WiFi, bed sheets
Best Inn of Manning
Best Inn of Manning
2.5 star property
Manning
7.0 out of 10, Good, (20 reviews)
The price is $71
$79 total
includes taxes & fees
Mar 26 - Mar 27
Best Inn of Manning
Deluxe Room, 1 King Bed, Non Smoking | Iron/ironing board, free WiFi, bed sheets
Baymont by Wyndham Manning
Baymont by Wyndham Manning
2.5 star property
Manning
6.8 out of 10, (1,001 reviews)
  • cleanliness
    Manning hotel with free breakfast and parking for easy SC travel.
The price is $78
$87 total
includes taxes & fees
Apr 5 - Apr 6
Baymont by Wyndham Manning
Free buffet breakfast
Quality Inn Manning I-95
Quality Inn Manning I-95
2.5 star property
Manning
6.8 out of 10, (510 reviews)
  • cleanliness
    Rest peacefully at this Manning hotel just off I-95 with free parking and breakfast.
The price is $80
$89 total
includes taxes & fees
Mar 25 - Mar 26
Quality Inn Manning I-95
Reception
Super 8 by Wyndham Manning
Super 8 by Wyndham Manning
2.0 star property
Manning
6.4 out of 10, (396 reviews)
  • cleanliness
    Located in Manning with helpful staff and convenient freebies like WiFi and breakfast.
The price is $60
$67 total
includes taxes & fees
Mar 31 - Apr 1
Super 8 by Wyndham Manning
1 bedroom
Starlight Stays
Starlight Stays
2.5 star property
Manning
7.4 out of 10, Good, (8 reviews)
  • cleanliness
    Tranquil Manning retreat near Wyboo Golf Club with complimentary parking.
The price is $66
$73 total
includes taxes & fees
Mar 25 - Mar 26
Starlight Stays
Panoramic Tent | Lake view
Bells Marina & Resort
Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (91 reviews)
  • cleanliness
    Tucked away on the water, this Eutawville resort offers marina access and golf.
The price is $105
$120 total
includes taxes & fees
Mar 25 - Mar 26
Bells Marina & Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Showing deals for:Mar 24 - Mar 25
Free daily buffet breakfast
Tru By Hilton Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (769 reviews)
The price is $138
per night
$153 total
includes taxes & fees
Tru By Hilton Santee
Showing deals for:Mar 25 - Mar 26
Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
7.8 out of 10, Good, (1,425 reviews)
The price is $80
per night
$89 total
includes taxes & fees
Baymont by Wyndham Santee
Showing deals for:Apr 3 - Apr 5
Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
7.8 out of 10, Good, (1,425 reviews)
The price is $100
per night
$222 total
includes taxes & fees
MOD
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Baymont by Wyndham Santee

Check out pet-friendly hotels in Santee

Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
7.8 out of 10, Good, (1425)
The price is $80
$89 total
includes taxes & fees
Mar 25 - Mar 26
Baymont by Wyndham Santee
View all properties

You may also like hotels with pools in Santee

Exterior
Best Western Plus Santee Inn

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1006)
The price is $119
$132 total
includes taxes & fees
Mar 30 - Mar 31
Best Western Plus Santee Inn
View all properties

You can also stay at family-friendly hotels in Santee

Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1003)
The price is $143
$159 total
includes taxes & fees
Apr 5 - Apr 6
Fairfield Inn & Suites by Marriott Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit Santee?

Our prices for hotels in Santee are cheapest in January
Price trends for hotels in Santee
Pricing is based on two traveler single night rates
View properties in March
Currently viewing crowd sizes and weather for March.
Typical weather for Santee
March
High 19°C / low 9°C. Sunny most days.
View properties in March
19°
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March, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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24°
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April, no crowd data, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
28°
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May, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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31°
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June, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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33°
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July, no crowd data, average high temperature 33 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
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32°
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August, no crowd data, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
29°
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September, no crowd data, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
24°
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October, no crowd data, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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19°
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November, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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15°
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December, no crowd data, average high temperature 15 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
7°
13°
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January, no crowd data, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
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16°
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February, no crowd data, average high temperature 16 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
6°
Monthly weather averages (˚C)

Top landmarks in Santee

Santee State Park

4.0/5 (112 reviews)
Rent a pier cabin at Santee State Park for unmatched views of South Carolina's largest lake. Explore 10 miles of trails winding through cypress swamps where alligators and diverse bird species await.
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Santee Cooper Country Club

3.9/5 (47 reviews)
Wind through majestic pines on George Cobb's scenic 18-hole course overlooking Lake Marion. The signature closing hole offers a panoramic view that makes the challenging doglegs and strategic bunkering worth every swing.
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Learn more about Santee

Tee off at championship golf courses or cast a line in Lake Marion's fish-rich waters where locals claim the bass practically jump into your boat. The Santee National Wildlife Refuge offers hiking trails where alligators sun themselves with reptilian nonchalance. Interstate 95 crosses the lake on a causeway that provides views worth pulling over for (safely, of course). Santee State Park delivers lakeside tranquility that makes visitors forget their phones exist. This resort town punches well above its weight with dining options that range from fresh-caught catfish to surprisingly sophisticated fare. The recent addition of the Santee Cooper Regional Water System has locals buzzing about growth while still cherishing their small-town atmosphere.

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Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Check out reviews of Santee hotels guests love

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

6/10 Okay
"Second time staying here. Adequate for the cost and our needs. Great location; close proximity to amenities. Easy check-in; friendly, courteous employees. Clean, large ground floor room with comfortable bed, small fridge and microwave. Convenient parking right in front of room."
Judy 1-night trip
Posted 4 hours ago
Travelodge by Wyndham Santee

Frequently asked questions

What accommodations do travelers like in Santee?
Hampton Inn Santee-I-95, Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee are all accommodations that are popular with guests.
Can I book refundable accommodations in Santee?
If you want the flexibility to change your plans to Santee, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where should I stay in Santee if I'm looking for a reasonably priced accommodation?
A few inexpensive options worth considering are Baymont by Wyndham Santee, Tru By Hilton Santee and Best Western Plus Santee Inn.
Where can I stay in Santee if I want a vacation rental instead of a hotel?
Browse 8 vacation homes on our site. You also might want to book one of 97 condos for your trip.
What will the weather in Santee be like during my vacation?
July and August are typically the warmest months in Santee when the average temp is 79°F. January and February are the coldest months when the average temperature is 52°F. August and July are the months with the most rain.
Why should I book my Santee hotel with Hotels.com?
There are lots of reasons to book your Santee trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.