Hotels in La Mesilla

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in La Mesilla?

Casa Escondida Bed & Breakfast
Casa Escondida Bed & Breakfast
3.0 star property
Chimayo
9.4 out of 10, Exceptional, (270 reviews)
Wake up to complimentary full breakfast at this charming adobe retreat just minutes from Chimayo Museum and Trading Mercantile. Guests love the helpful staff, garden terrace, and peaceful grounds with free WiFi and parking.
The price is $168
$188 total
includes taxes & fees
Apr 17 - Apr 18
Casa Escondida Bed & Breakfast
Bishop's Lodge, Auberge Collection
Bishop's Lodge, Auberge Collection
5.0 star property
Tesuque
9.4 out of 10, Exceptional, (103 reviews)
Escape to this secluded resort nestled in the mountains near Santa Fe Plaza. Rejuvenate at the full-service spa with deep-tissue massages, then lounge by the outdoor pool with cocktails from the poolside bar. Meow Wolf and Shidoni Foundry await nearby.
The price is $719
$866 total
includes taxes & fees
May 10 - May 11
Bishop's Lodge, Auberge Collection
Four Seasons Resort Rancho Encantado Santa Fe
Four Seasons Resort Rancho Encantado Santa Fe
5.0 star property
Santa Fe
9.4 out of 10, Exceptional, (278 reviews)
This luxurious resort features an outdoor pool and American cuisine at Terra restaurant. Indulge in deep-tissue massages or reflexology at the full-service spa, just minutes from Tesuque Casino and Santa Fe Opera. A poolside bar and 24-hour fitness center complete your retreat.
The price is $616
$753 total
includes taxes & fees
May 10 - May 11
Four Seasons Resort Rancho Encantado Santa Fe
Hotel Glorieta
Hotel Glorieta
3.5 star property
Santa Fe
8.4 out of 10, Very Good, (185 reviews)
Escape to a peaceful sanctuary with spectacular views in Santa Fe. Minutes from downtown shopping and Meow Wolf, this hotel offers a seasonal outdoor pool, hot tub, and 24-hour fitness center. Enjoy a meal at the restaurant or drink at the garden-side lounge.
The price is $121
$168 total
includes taxes & fees
May 7 - May 8
Hotel Glorieta
Homewood Suites by Hilton Santa Fe-North
Homewood Suites by Hilton Santa Fe-North
3.0 star property
Santa Fe
9.2 out of 10, Wonderful, (1,001 reviews)
Embrace the Southwest vibe at this golf-adjacent hotel featuring an outdoor pool and 24-hour fitness center. Just minutes from Buffalo Thunder Resort and Casino, this Santa Fe retreat offers free breakfast, parking, and spacious rooms with sofa beds and refrigerators.
The price is $153
$175 total
includes taxes & fees
Apr 26 - Apr 27
Homewood Suites by Hilton Santa Fe-North
Hilton Santa Fe Buffalo Thunder
Hilton Santa Fe Buffalo Thunder
4.0 star property
Santa Fe
8.8 out of 10, Excellent, (1,077 reviews)
The price is $134
$154 total
includes taxes & fees
May 10 - May 11
Hilton Santa Fe Buffalo Thunder
Cities Of Gold Casino
Cities Of Gold Casino
3.0 star property
Santa Fe
8.2 out of 10, Very Good, (1,127 reviews)
A tranquil escape with convenient proximity to Santa Fe and nearby attractions like Don Quixote Distillery. Test your luck at the casino, work out at the fitness center, or relax at the bar. Clean rooms, helpful staff, and free WiFi and parking enhance your stay.
The price is $76
$86 total
includes taxes & fees
Apr 19 - Apr 20
Cities Of Gold Casino
Ohkay Casino Resort Hotel
Ohkay Casino Resort Hotel
2.5 star property
Ohkay Owingeh
8.0 out of 10, Very Good, (822 reviews)
Escape to this vibrant casino resort featuring a seasonal outdoor pool and lively nightclub. Enjoy American cuisine at Festival Buffet and drinks at the bar after a day exploring nearby Tesuque Peak Trail. Clean rooms, free WiFi, and attentive staff enhance your stay.
The price is $107
$120 total
includes taxes & fees
Apr 25 - Apr 26
Ohkay Casino Resort Hotel
Motel 6 Espanola, NM
Motel 6 Espanola, NM
2.0 star property
Espanola
6.4 out of 10, (524 reviews)
This budget-friendly motel offers 24-hour front desk service and complimentary WiFi in a convenient location. The well-lit, safe parking lot provides peace of mind while exploring nearby attractions like Bond House Museum and Tesuque Peak Trail.
The price is $89
$101 total
includes taxes & fees
Apr 17 - Apr 18
Motel 6 Espanola, NM
Days Inn by Wyndham Espanola
Days Inn by Wyndham Espanola
2.0 star property
Espanola
5.8 out of 10, (602 reviews)
Wake up to a complimentary continental breakfast at this Espanola hotel, perfectly positioned for downhill ski enthusiasts. Enjoy convenient amenities including free WiFi and parking, plus easy access to Bond House Museum and Tesuque Peak Trail.
The price is $89
$101 total
includes taxes & fees
Apr 17 - Apr 18
Days Inn by Wyndham Espanola
Rodeway Inn Española
Rodeway Inn Española
2.0 star property
Espanola
6.2 out of 10, (483 reviews)
Free breakfast, WiFi, and parking await at this tranquil hotel near Bond House Museum. Guests consistently praise the property's peaceful atmosphere and well-maintained facilities, with Tesuque Peak Trail adventures just a short drive away.
The price is $60
$68 total
includes taxes & fees
May 17 - May 18
Rodeway Inn Española
The Inn at the Delta
The Inn at the Delta
3.0 star property
Espanola
9.4 out of 10, Exceptional, (1,002 reviews)
Discover the charm of this welcoming B&B in Espanola, where spacious rooms await. Free WiFi and parking make exploring easy, with Bond House Museum and Tesuque Peak Trail nearby. The attentive staff ensures a memorable northern New Mexico stay.
The price is $165
$188 total
includes taxes & fees
Apr 19 - Apr 20
The Inn at the Delta
Hampton Inn & Suites Los Alamos White Rock
Hampton Inn & Suites Los Alamos White Rock
2.5 star property
Los Alamos
9.0 out of 10, Wonderful, (700 reviews)
The price is $114
$128 total
includes taxes & fees
Apr 25 - Apr 26
Hampton Inn & Suites Los Alamos White Rock
Holiday Inn Express & Suites Los Alamos Entrada Park by IHG
Holiday Inn Express & Suites Los Alamos Entrada Park by IHG
2.5 star property
Los Alamos
8.8 out of 10, Excellent, (768 reviews)
Wake up to a complimentary breakfast before exploring Bradbury Science Museum and Karen Wray Fine Art Gallery. This hotel offers an indoor pool for morning swims, hot tub, fitness center, and free WiFi with parking.
The price is $136
$152 total
includes taxes & fees
Apr 25 - Apr 26
Holiday Inn Express & Suites Los Alamos Entrada Park by IHG
Wingate by Wyndham Los Alamos
Wingate by Wyndham Los Alamos
2.5 star property
Los Alamos
8.0 out of 10, Very Good, (594 reviews)
Set in a prime location for hikers and skiers, this hotel offers free breakfast, WiFi, and parking near local attractions. The fitness center provides post-trail workouts, while the attentive staff ensures a comfortable stay just 4 minutes from the county airport.
The price is $121
$135 total
includes taxes & fees
Apr 18 - Apr 19
Wingate by Wyndham Los Alamos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check out reviews of La Mesilla hotels guests love

Frequently asked questions

What accommodations do travelers recommend in La Mesilla?
Can I book a refundable hotel in La Mesilla?
If you need the flexibility to change your plans to La Mesilla, most properties provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in La Mesilla be like during my trip?
The warmest months in La Mesilla are usually July and June with an average temp of 70°F. January and December are the chilliest months when the average temp is 33°F. The rainiest months are September and July.
Why should I book my La Mesilla hotel through Hotels.com?
There are plenty of reasons to book your La Mesilla travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.