Top 10 Hotels in Frohna, MO in 2026 (from $59)

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Where to stay in Frohna?

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

A hotel room with two beds, a brick wall, and a wooden headboard.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

1. Drury Inn & Suites Jackson MO

Jackson

$84

$89 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A kitchen counter with a coffee machine, a kettle, and storage boxes.

A swimming pool with a diving board, pool rules signs, and lounge chairs.

A hotel lobby with a seating area, a reception desk, and a bar.

2. Holiday Inn Express & Suites Perryville by IHG

Perryville

$103

$118 total

includes taxes & fees

Oct 31 - Nov 1

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

3. Super 8 by Wyndham Perryville

Perryville

$71

$82 total

includes taxes & fees

Oct 6 - Oct 7

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

$84

$91 total

includes taxes & fees

Oct 4 - Oct 5

A modern retail area with a display of local items and snacks.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

5. Tru By Hilton Cape Girardeau

Cape Girardeau

$89

$102 total

includes taxes & fees

Oct 8 - Oct 9

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A swimming pool with a small water slide, surrounded by lounge chairs and umbrellas.

A playground with a wooden playhouse, a slide, and two animal-shaped swings.

A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

6. Perryville RV Resort

Perryville

$66

$76 total

includes taxes & fees

Oct 1 - Oct 2

A lobby with a TV, framed pictures, a plant, and patterned chairs.

A hotel reception desk with a sign that reads "Quality by Choice Hotels."

A hotel room with a desk, a television, a coffee maker, a chair, and a window with curtains.

A hotel room with a large bathtub, a bed with two pillows, a nightstand, and a wall-mounted lamp.

7. Quality Inn Perryville I-55

Perryville

$64

$73 total

includes taxes & fees

Oct 20 - Oct 21

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

A building with a sign that reads "The Atrium Boutique Hotel".

8. The Atrium - A Boutique Hotel

Perryville

$84

$170 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

A reception area with a blue couch, a wooden table with a vase of flowers, and a reception desk with a digital screen.

A swimming pool with a metal ladder, a Days Inn sign, and a blue water tower in the background.

A hotel hallway with a patterned carpet, blue walls, and a sign indicating an office.

9. Days Inn by Wyndham Perryville

Perryville

$71

$82 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

10. Comfort Suites Jackson-Cape Girardeau

Jackson

$77

$83 total

includes taxes & fees

Oct 22 - Oct 23

A hotel room with a bed, a desk with a chair, a small table, a sofa, a bathtub, and a window with curtains.

A breakfast area with a counter, seating, and kitchen appliances.

A room with a fireplace, a mounted deer head, a bookshelf, and two armchairs.

A gym with treadmills, a weight machine, and exercise balls.

11. Baymont by Wyndham Chester IL

Chester

$89

$99 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with two beds, a desk, a chair, a TV, and a projector screen.

An indoor swimming pool with four lounge chairs and a metal ladder.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

A reception area with two reception desks, a wall-mounted sign, and a refrigerator.

12. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

$105

$117 total

includes taxes & fees

Oct 28 - Oct 29

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

13. Quality Inn Cape Girardeau North

Cape Girardeau

$60

$68 total

includes taxes & fees

Oct 11 - Oct 12

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

14. Town House Inn

Jackson

$71

$77 total

includes taxes & fees

Oct 1 - Oct 2

A log cabin with a wooden deck, a door, and a small window.

A gravel path leading to a lake with cabins and a sign indicating Blue Line Resort.

A large outdoor area with a pond, several wooden cabins, and a road.

A compact kitchen with wooden cabinets, a microwave, a trash bin, and a dining table with placemats.

15. Pet Friendly! Couples Retreat in Southern Illinois

Murphysboro

$120

$235 total

includes taxes & fees

Oct 1 - Oct 2

An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.

A spacious lobby with a central seating area, a large window, and a reception desk.

A hotel with a covered entrance, outdoor seating, and a flag.

A modern kitchen with a stainless steel refrigerator, microwave, and dishwasher. There is a window providing natural light and a view of the outdoors.

16. Home2 Suites by Hilton Carbondale

Carbondale

$119

$137 total

includes taxes & fees

Oct 27 - Oct 28

A room with a brown sofa, a brown armchair, a patterned carpet, a lamp, and a window with curtains.

A hotel room with a large bed, a desk, a chair, a window with curtains, a wall-mounted TV, and a large painting.

A hotel lobby with a reception desk, several tables and chairs, framed pictures on the walls, and a clock.

A hotel with a Super 8 sign, multiple parking spaces, and a brick facade.

17. Super 8 by Wyndham Carbondale

Carbondale

$65

$75 total

includes taxes & fees

Oct 13 - Oct 14

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

A hallway with exposed brick walls, wooden flooring, and a white door.

18. Urban Lofts

Perryville

$224

$338 total

includes taxes & fees

Oct 1 - Oct 2

A building with a covered entrance, a parking lot, and a tree.

A hotel lobby with leather sofas, a reception desk, an exit sign, and a view of the outdoors.

A hotel reception area with a reception desk, a TV, and a seating area with a sofa and table.

A hotel room with a bed, desk, chair, television, and a window with curtains.

19. Quality Inn Carbondale University area

Carbondale

$62

$71 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with two beds, a desk, a chair, a TV, a lamp, and a painting on the wall.

A modern hotel lobby with leather sofas, a flat-screen TV, and framed artwork on the walls.

A bar area with multiple stools, a bar counter, shelves of liquor bottles, and hanging pendant lights.

An indoor swimming pool with clear blue water, a sunshade, and a seating area with chairs and a table.

20. Best Western Saluki Inn

Carbondale

$91

$107 total

includes taxes & fees

Oct 13 - Oct 14

View all properties

Go beyond your typical stay in Frohna

Check out reviews of Frohna hotels guests love

Best Western Saluki Inn

Carbondale

10/10 Exceptional

Akash

Drury Inn & Suites Jackson MO

Jackson

10/10 Exceptional

Nicole

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

10/10 Exceptional

Alexandra

Tru By Hilton Cape Girardeau

Cape Girardeau

10/10 Exceptional

Tara

Super 8 by Wyndham Perryville

Perryville

10/10 Exceptional

DAN

Baymont by Wyndham Chester IL

Chester

10/10 Exceptional

Michael

Days Inn by Wyndham Perryville

Perryville

10/10 Exceptional

Anonymous traveler

Town House Inn

Jackson

10/10 Exceptional

larry

Urban Lofts

Perryville

10/10 Exceptional

Gregory

Super 8 by Wyndham Carbondale

Carbondale

10/10 Exceptional

Anonymous traveler

Frequently Asked Questions

Can I book a refundable accommodation in Frohna?

If you're looking for the flexibility to change your plans to Frohna, most accommodations offer refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Frohna be like during my trip?

July and August are typically the warmest months in Frohna when the average temp is 75°F. January and February are the coldest months when the average temperature is 39°F. April and May are the months with the most rain.

Why should I book my Frohna hotel with Hotels.com?

There are lots of reasons to book your Frohna trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.