Hotels in Mesquite

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in Mesquite?

A lobby with a stone fireplace, sofas, and a glass coffee table.

A living room with a sofa, ottoman, TV, and a desk with a chair. There is a kitchen in the background.

A courtyard with outdoor seating, a small tree, and a stone wall.

An indoor swimming pool with a hot tub, tiled flooring, and a high ceiling with beams.

Drury Inn & Suites Las Cruces

Las Cruces

$94

$109 total

includes taxes & fees

Aug 30 - Aug 31

A buffet area with a variety of baked goods, a coffee station, and a decorative plant.

A cozy living room with a wooden sofa and armchair, a wooden coffee table, and a patterned rug.

A hotel room with two beds, wooden benches, a desk, and a chair.

A patio with a table and chairs, a large tree, a fountain, and a pool in the background.

Best Western Mission Inn

Las Cruces

$77

$89 total

includes taxes & fees

Aug 24 - Aug 25

A spacious lobby with a high ceiling, a central chandelier, and large windows allowing natural light.

An outdoor patio with a built-in fireplace, surrounded by yellow cushioned chairs and a pergola overhead.

A hotel with a distinctive arched entrance and a clear sign reading "Hilton Garden Inn."

A spacious living room with a fireplace, leather sofas, a wooden coffee table with fruit, and patterned rugs.

Hilton Garden Inn Las Cruces

Las Cruces

$101

$117 total

includes taxes & fees

Aug 30 - Aug 31

A spacious hotel lobby with a modern design, featuring a reception desk, seating area, and potted plants.

A hotel room with a bed, a sofa, a desk, and a TV. There are framed pictures on the wall.

An indoor swimming pool with clear water, a diving board, and lounge chairs.

A modern hotel room with a blue sofa, armchairs, a flat-screen TV, and framed pictures on the wall.

Comfort Suites University Las Cruces

Las Cruces

$83

$97 total

includes taxes & fees

Sep 13 - Sep 14

A Days Inn with a large sign, a flag, and a well-maintained entrance area.

A hotel room with a bed, desk, chair, and a painting on the wall.

A hotel lobby with a reception desk, seating area, and a kitchenette.

An outdoor patio with wooden benches and a grill area.

Days Inn by Wyndham Las Cruces

Las Cruces

$48

$57 total

includes taxes & fees

Sep 1 - Sep 2

A spacious indoor courtyard with tiled flooring, wooden furniture, and a balcony with a railing.

A dining area with a table and chairs, a remote control on a rug, and a door leading to another room.

A hotel room with a large bed, a television, a desk, and a chair.

A lobby with a tiled floor, a staircase, and a patterned wall hanging.

Ramada Hotel & Conference Center by Wyndham Las Cruces

Las Cruces

$79

$92 total

includes taxes & fees

Sep 1 - Sep 2

A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

A covered outdoor area with a patio, seating, and a small lawn.

A golf course with a mountain range in the background.

Comfort Inn & Suites Las Cruces Mesilla

Las Cruces

$95

$111 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with two beds, a desk with a TV, a chair, and two lamps.

A living room with striped sofas, a glass coffee table, a fireplace, and a television.

A multi-story hotel with a central entrance, balconies, and a parking area.

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

Las Cruces

$57

$67 total

includes taxes & fees

Sep 13 - Sep 14

A spacious lobby with a central dining area, multiple seating options, and a modern chandelier.

A gym with treadmills, elliptical machines, and exercise bikes.

A lobby with teal armchairs, a coffee bar, and a dining area.

An indoor swimming pool with clear water, tiled edges, and a metal safety railing.

Hampton Inn & Suites Las Cruces I-10

Las Cruces

$118

$136 total

includes taxes & fees

Aug 30 - Aug 31

A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows allowing natural light.

A hotel room with a sofa, a dining table, a kitchen area with a microwave, refrigerator, and sink.

A swimming pool with lounge chairs and a sunshade.

A spacious living area with a fireplace, comfortable seating, and a television.

Hampton Inn & Suites Las Cruces I-25

Las Cruces

$98

$113 total

includes taxes & fees

Aug 30 - Aug 31

An outdoor patio area with seating arrangements, including sofas and chairs, under a covered structure with a wooden ceiling.

A modern coffee shop interior with a wooden counter, seating area, and menu boards.

A modern bar area with a long counter, bar stools, and a variety of liquor bottles.

A Courtyard by Marriott hotel with a modern facade, multiple windows, and a covered entrance area.

Courtyard by Marriott Las Cruces at NMSU

Las Cruces

$134

$155 total

includes taxes & fees

Aug 30 - Aug 31

A pool area with a fountain, palm trees, and outdoor seating.

A hallway with a tiled floor, a chandelier, potted plants, and a cross at the end.

A brick pathway lined with lush greenery and stone columns, leading to a covered area with a pergola.

A fountain with a lotus design in a pool, surrounded by a balustrade and palm trees.

Hotel Encanto de Las Cruces

Las Cruces

$118

$164 total

includes taxes & fees

Aug 23 - Aug 24

A hotel with a pool area, stone walls, and a palm tree.

A hotel with a central courtyard, multiple balconies, and a stone wall.

A hotel kitchen with a coffee station, a fresh juice dispenser, and various cooking appliances.

A reception desk with a wooden finish and decorative diamond patterns, a wall-mounted sign reading "Quality by Choice Hotels," and a framed picture on the wall.

Quality Inn & Suites Las Cruces - University Area

Las Cruces

$53

$63 total

includes taxes & fees

Sep 11 - Sep 12

A hotel room with a bed, a TV mounted on the wall, a desk, and a sofa.

A compact kitchenette with a microwave, a small sink, and a refrigerator.

A small, modern kitchenette with a white countertop, a sink, and a compact refrigerator.

A modern hotel with a flat roof, large windows, and a well-lit entrance.

Springhill Suites By Marriott Las Cruces

Las Cruces

$112

$129 total

includes taxes & fees

Aug 29 - Aug 30

A hotel room with a large bed, two bedside lamps, a desk with a chair, a window with curtains, and a cityscape painting on the wall.

A hotel lobby with a reception desk, seating area, and a ceiling fan.

A hotel with a stone facade, a covered entrance, and a parking lot.

A dining area with multiple tables and chairs, a kitchen area with a refrigerator and a coffee machine, and a television mounted on the wall.

Super 8 by Wyndham Las Cruces/White Sands Area

Las Cruces

$51

$60 total

includes taxes & fees

Sep 11 - Sep 12

A living room with a sofa, two armchairs, a coffee table, and a lamp.

A spacious lobby with a wooden staircase, a seating area with two armchairs and a table, and a green wall with a leaf pattern.

A hotel room with a bed, a desk with a television, a chair, and a wardrobe.

A modern dining area with tables and chairs, a kitchen area with appliances, and artwork on the walls.

Sleep Inn University

Las Cruces

$59

$69 total

includes taxes & fees

Sep 13 - Sep 14

A pool area with a hot tub, lounge chairs, and a lifeguard stand.

A spacious living area with a fireplace, a television mounted above it, and a seating arrangement including a sofa and chairs.

A hotel room with a blue accent wall, a sofa, a bed, a desk, and a mirror.

A hotel with a modern design, featuring a covered entrance and multiple floors.

Comfort Suites Las Cruces I-25 North

Las Cruces

$104

$125 total

includes taxes & fees

Sep 13 - Sep 14

A spacious living room with a dark wooden coffee table, patterned armchairs, a grey sofa, and a red and orange patterned rug.

A living room with a fireplace, two patterned armchairs, a sofa, a coffee table, and a decorative rug.

A spacious dining area with multiple tables and chairs, a kitchen in the background, and a large screen on the wall.

A hotel room with a bed, a sofa, a desk, and a nightstand.

Best Western Anthony/West El Paso

Anthony

$109

$125 total

includes taxes & fees

Aug 23 - Aug 24

A vending machine, a refrigerator, and a display of travel brochures.

A coffee machine with a coffee cup and a sign above it that says "RISE & SHINE".

An indoor swimming pool with two lanes, safety railings, and clear signage including pool capacity and no diving allowed.

A hotel room with two beds, a refrigerator, a desk with a chair, a mirror, and a window with curtains.

Studio 6 – Las Cruces, NM - Telshor

Las Cruces

$59

$69 total

includes taxes & fees

Aug 23 - Aug 24

An outdoor seating area with a fire pit, sofas, and chairs.

A modern hotel room with a wooden desk, a grey sofa, a small ottoman, a television, and a bed with a white headboard.

A modern cafe with an 'inspired table' sign, a 'good morning' greeting, and a variety of seating options including tables and chairs.

A modern lounge area with a sofa, chairs, and tables, featuring pendant lighting and large windows.

Home2 Suites by Hilton Las Cruces

Las Cruces

$126

$146 total

includes taxes & fees

Sep 7 - Sep 8

View all properties

Go beyond your typical stay in Mesquite

Pet friendly

Hot tub

Pool

Family friendly

Check out reviews of Mesquite hotels guests love

Drury Inn & Suites Las Cruces

8/10 Good

"Had a wonderful breakfast. The staff were super accommodating."

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

10/10 Excellent

"Great for travelers!"

Days Inn by Wyndham Las Cruces

8/10 Good

"I wish that I had read more details about this place. I looked at reviews and price. I want to preface by saying this isn't a bad place! It's over-all clean, the bed was comfortable, and the shower pressure was amazing. Those things are really the only thing that matters. However, the amenities are not there in the room like free bottles of shampoo or conditioner. I couldn't wash my hair because I didn't know I needed to bring my own shampoo. I would say that this is a motel vs. hotel. You drive up to the room vs within a building. I prefer a building vs easy access as a single woman. I can't speak for the breakfast because I didn't go. You won't be disappointed if you go with this information."

Motel 6 El Paso, TX - West

10/10 Excellent

"We are very satisfied staying there, from beginning to the end. We felt there secure us two women with two children from Germany. Lots of greetings."

La Quinta Inn by Wyndham El Paso West

8/10 Good

"Esta bien en general pero la alberca me toco en reparación ya esta lista cuando me boy"

Holiday Inn Express & Suites Las Cruces North by IHG

10/10 Excellent

"Great location, staff is super friendly, breakfast was excellent."

Frequently asked questions

What accommodations do travelers like in Mesquite?

Guests like Ramada Hotel & Conference Center by Wyndham Las Cruces and Comfort Suites University Las Cruces.

Can I book refundable accommodations in Mesquite?

If you need the flexibility to change your plans to Mesquite, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Mesquite be like during my trip?

June and July are typically the warmest months in Mesquite when the average temp is 82°F. January and December are the coldest months when the average temperature is 48°F. August and September are the months with the most rain.

Why should I book my Mesquite hotel with Hotels.com?

There are lots of reasons to book your Mesquite trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

More ways to book

Book Hotels in Mesquite on Hotels.com