Photo by Nico Barner

Hotels in Eastern Panama

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

This weekend
Next weekend

Where to stay in Eastern Panama?

Private Bedroom on Paradise San Blas Island
Private Bedroom on Paradise San Blas Island
2.5 star property
Narganá
10.0 out of 10, Exceptional, (1 review)
  • cleanliness
    Wake to crystal waters in this slice of San Blas Island paradise.
The price is $166
$183 total
includes taxes & fees
Mar 27 - Mar 28
Private Bedroom on Paradise San Blas Island
San Blas Private Oceanfront Cabin
San Blas Private Oceanfront Cabin
2.5 star property
Narganá
  • cleanliness
    Escape to a serene beach cabin in Narganá with complimentary morning meals.
The price is $259
$385 total
includes taxes & fees
Mar 27 - Mar 28
San Blas Private Oceanfront Cabin
San Blas Private Beach Cabin
San Blas Private Beach Cabin
2.5 star property
Narganá
  • cleanliness
    Oceanside cabin in Narganá offers tranquil beach stays with easy island access.
San Blas Private Beach Cabin
Ranchos de Chalia
Ranchos de Chalia
3.0 star property
Puerto Lindo
9.8 out of 10, Exceptional, (17 reviews)
  • cleanliness
    Relax in Puerto Lindo Bay with convenient access to top local attractions.
The price is $117
$129 total
includes taxes & fees
Mar 29 - Mar 30
Ranchos de Chalia
Private Ocean-Front Cabin with private bathroom on San Blas Island
Private Ocean-Front Cabin with private bathroom on San Blas Island
2.0 star property
Narganá
10.0 out of 10, Exceptional, (1 review)
  • cleanliness
    Oceanfront hideaway in San Blas Islands offers breathtaking views and island charm.
Private Ocean-Front Cabin with private bathroom on San Blas Island
Ciel y Miel
Ciel y Miel
3.0 star property
Cacique
10.0 out of 10, Exceptional, (10 reviews)
  • cleanliness
    Coastal getaway with spa treatments and four pools at the bay's edge in Cacique.
Ciel y Miel
Hotel Cocotal
Hotel Cocotal
2.5 star property
Isla Grande
9.0 out of 10, Wonderful, (8 reviews)
  • cleanliness
    Beach paradise with 20 restaurants and bars for your tropical getaway.
The price is $59
$109 total
includes taxes & fees
Apr 6 - Apr 7
Hotel Cocotal
Ordovician Beach Resort
Ordovician Beach Resort
4.5 star property
Isla Grande
10.0 out of 10, Exceptional, (9 reviews)
  • cleanliness
    Beachfront luxury resort with free cabanas and massages on a private shoreline.
The price is $500
$549 total
includes taxes & fees
Mar 26 - Mar 27
Ordovician Beach Resort
Discovery Gunayar
Discovery Gunayar
2.0 star property
Narganá
6.0 out of 10, (1 review)
  • cleanliness
    Stay in a serene beach lodge with nearby islands and free morning meals.
Discovery Gunayar
Konsenda San Blas
Konsenda San Blas
2.0 star property
El Llano
10.0 out of 10, Exceptional, (2 reviews)
  • cleanliness
    A cozy getaway in El Llano with complimentary breakfast and parking.
The price is $45
$50 total
includes taxes & fees
Mar 26 - Mar 27
Konsenda San Blas
Private Over-Water Cabins on San Blas Island
Private Over-Water Cabins on San Blas Island
2.5 star property
Narganá
  • cleanliness
    Snorkel in paradise at this oceanfront cabin with free daily breakfast in Narganá.
The price is $209
$330 total
includes taxes & fees
Mar 26 - Mar 27
Private Over-Water Cabins on San Blas Island
Cocoloco - Catamaran Lagoon 52F SAN BLAS
Cocoloco - Catamaran Lagoon 52F SAN BLAS
3.0 star property
Narganá
  • cleanliness
    Sail the stunning San Blas archipelago on a floating paradise with sea views.
The price is $2,045
$2,250 total
includes taxes & fees
Mar 26 - Mar 27
Cocoloco - Catamaran Lagoon 52F SAN BLAS
Cabins on paradise San Blas island
Cabins on paradise San Blas island
2.0 star property
Narganá
  • cleanliness
    Explore Panama's San Blas island from a rustic cabin steps away from paradise.
Cabins on paradise San Blas island
Trips Guna Yala
Trips Guna Yala
2.0 star property
Narganá
  • cleanliness
    Retreat to pristine Guna Yala with pool and daily breakfast in tropical Panama.
The price is $104
$240 total
includes taxes & fees
Mar 26 - Mar 27
Trips Guna Yala
Sanblastourgy
Sanblastourgy
2.0 star property
Nargana
The price is $251
$276 total
includes taxes & fees
Mar 26 - Mar 27
Sanblastourgy
Cabins in Asserya Island - San Blas paradise - meals included
Cabins in Asserya Island - San Blas paradise - meals included
2.0 star property
Ailigandi
  • cleanliness
    Experience San Blas with seaside cabins and island meals included in paradise.
Cabins in Asserya Island - San Blas paradise - meals included
San Blas Tour Aridub
San Blas Tour Aridub
2.0 star property
Narganá
  • cleanliness
    Oceanfront cabins offering authentic San Blas adventure with beach access.
The price is $86
$144 total
includes taxes & fees
Mar 26 - Mar 27
San Blas Tour Aridub
Paradise Over the Water Cabins in San Blas
Paradise Over the Water Cabins in San Blas
2.5 star property
Narganá
6.0 out of 10, (1 review)
  • cleanliness
    Oceanside cabin retreat with a free breakfast on the San Blas Islands.
Paradise Over the Water Cabins in San Blas
Cabañas Isla Nubesidub San Blas
Cabañas Isla Nubesidub San Blas
2.0 star property
Narganá
Cabañas Isla Nubesidub San Blas
San Blas Private Over-the-Water Cabin
San Blas Private Over-the-Water Cabin
2.5 star property
Narganá
8.0 out of 10, Very Good, (2 reviews)
  • cleanliness
    Ocean cabin retreat with waterfront balconies and restaurant by Narganá shores.
San Blas Private Over-the-Water Cabin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Get last-minute hotel deals in Eastern Panama and save more

Sign in to unlock great savings.
Showing deals for:Apr 3 - Apr 5

You can also stay at hotels with a pool in Eastern Panama

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Eastern Panama

Learn more about Eastern Panama

Eastern Panama is well-known for its attractions such as Cayos Holandeses and Isla Diablo. The city has something for everyone including sights like Chagres National Park and Darien National Park within a tropical setting.

50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience  a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. 
#BVSBlue
Photo by Nico Barner
Open Photo by Nico Barner

Check out reviews of Eastern Panama hotels guests love

Frequently asked questions

Why should I book my Eastern Panama hotel with Hotels.com?
There are plenty of reasons to book your Eastern Panama travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.