Photo by De Smet Development Corporation

Hotels in Eastern South Dakota

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Nov 11 - Nov 12
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Nov 12 - Nov 13
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Nov 14 - Nov 16
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Nov 21 - Nov 23

Where to stay in Eastern South Dakota?

Room, Multiple Beds, Accessible, Non Smoking | Desk, laptop workspace, soundproofing, iron/ironing board
Comfort Inn & Suites at Sanford Sports Complex
Comfort Inn & Suites at Sanford Sports Complex
2.5 star property
9.6 out of 10, Exceptional, (842)
The price is $94
$106 total
includes taxes & fees
Nov 24 - Nov 25
Comfort Inn & Suites at Sanford Sports Complex
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Eastern South Dakota, SD

Showing deals for:Nov 21 - Nov 23

Image gallery for Lewis and Clark Resort

32-inch LCD TV with digital channels, TV

Lewis and Clark Resort

2.5 star property
Yankton
8.8/10Excellent (278 reviews)
10% off
$124 nightly
Price is $262
Total includes taxes and fees
Lewis and Clark Resort

Check out pet-friendly hotels in Eastern South Dakota

Desk, blackout drapes, soundproofing, iron/ironing board
Days Inn by Wyndham Sioux Falls Airport

Days Inn by Wyndham Sioux Falls Airport

2.0 star property
North Sioux Falls
7.2 out of 10, Good, (1009)
The price is $59
$66 total
includes taxes & fees
Nov 17 - Nov 18
Days Inn by Wyndham Sioux Falls Airport
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You may also like hotels with hot tubs in Eastern South Dakota

Studio Suite, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Super 8 by Wyndham Sioux Falls

Super 8 by Wyndham Sioux Falls

2.0 star property
Sioux Falls
7.4 out of 10, Good, (1005)
The price is $69
$78 total
includes taxes & fees
Nov 12 - Nov 13
Super 8 by Wyndham Sioux Falls
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You can also stay at hotels with a pool in Eastern South Dakota

Room, Multiple Beds, Accessible, Non Smoking | Desk, laptop workspace, soundproofing, iron/ironing board
Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex

2.5 star property
Northwest Sioux Falls
9.6 out of 10, Exceptional, (842)
The price is $94
$106 total
includes taxes & fees
Nov 24 - Nov 25
Comfort Inn & Suites at Sanford Sports Complex
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top landmarks in Central United States

Beautiful park containing the famous Sioux Falls on the Sioux River in winter. What remains of a hundred year old mill can be seen. #waterfalls #siouxfalls #southdakota #travel #river #winter #ice #park #mill #localgem #snow
Photo by Erik Rowley
Open Photo by Erik Rowley

Falls Park

4.6/5 (1,189 reviews)
Falls Park is worth a pic or two when discovering Downtown Sioux Falls.
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Aerial View of a large University in Brookings, South Dakota

South Dakota State University

4.7/5 (170 reviews)
If you'd like to get a taste of Brookings student life, check out South Dakota State University, located 1 mi (1.6 km) from central Brookings.
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Learn more about Eastern South Dakota

Eastern South Dakota, well-known for its castle and university life, features attractions such as Ingalls Homestead and Lake Thompson Recreation Area. This family-friendly city has something for everyone including its live music, restaurants, and sights like Laura Ingalls Wilder Memorial and Prairie Village.

See all hotels in Eastern South Dakota
De Smet showing heritage elements and an administrative buidling
Photo by De Smet Development Corporation
Open Photo by De Smet Development Corporation

Check out reviews of Eastern South Dakota hotels guests love

Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex

10/10 Excellent
"Friendly staff"
Jo 1-night trip
Posted 3 days ago
Comfort Inn & Suites at Sanford Sports Complex

Frequently asked questions

Why should I book my Eastern South Dakota accommodation with Hotels.com?
There are plenty of reasons to book your Eastern South Dakota travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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