Photo by Fabrice Récalt
Hotels in Guadalupe
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Guest House Quinta Natural
Guest House Quinta Natural
3.0 star property
Trindade
10.0 out of 10, Exceptional, (1)
10/10
Exceptional
(1)
- Eco-friendly sanctuary in colonial property, minutes from Coffee Museum and waterfalls.
Mucumbli Hotel
Mucumbli Hotel
3.0 star property
Neves
9.4 out of 10, Exceptional, (26)
9.4/10
Exceptional
(26)
- Immerse in lush tropical gardens just steps away from São Tomé Island's coastline.
The price is $136
$136
$156 total
includes taxes & fees
Dec 21 - Dec 22
Praia Accommodation
Praia Accommodation
3.0 star property
São Tomé
7.2 out of 10, Good, (17)
7.2/10
Good
(17)
- Beachfront São Tomé escape with spa services and free airport transfers.
The price is $127
$127
$146 total
includes taxes & fees
Dec 25 - Dec 26
Omali São Tomé – Principe Collection
Omali São Tomé – Principe Collection
4.0 star property
São Tomé
9.4 out of 10, Exceptional, (62)
9.4/10
Exceptional
(62)
- Tropical beach retreat with poolside luxury and personal service on São Tomé Island.
The price is $214
$214
$251 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Praia
Hotel Praia
3.5 star property
São Tomé
7.6 out of 10, Good, (17)
7.6/10
Good
(17)
- Bask in island bliss near São Tomé airport with a free 24-hour shuttle service.
The price is $170
$170
$196 total
includes taxes & fees
Dec 21 - Dec 22
Hotel Kenito
Hotel Kenito
2.5 star property
São Tomé
10.0 out of 10, Exceptional, (3)
10/10
Exceptional
(3)
- Relax in São Tomé with a refreshing poolside escape close to cultural landmarks.
The price is $92
$92
$105 total
includes taxes & fees
Dec 21 - Dec 22
Hotel Central
Hotel Central
3.5 star property
São Tomé
8.2 out of 10, Very Good, (24)
8.2/10
Very Good
(24)
- Conveniently close to the airport with complimentary breakfast and parking.
The price is $56
$56
$65 total
includes taxes & fees
Dec 28 - Dec 29
SH Boutique Hotel
SH Boutique Hotel
3.5 star property
São Tomé
8.6 out of 10, Excellent, (10)
8.6/10
Excellent
(10)
Casa de Ferias
Casa de Ferias
3.0 star property
São Tomé
8.8 out of 10, Excellent, (6)
8.8/10
Excellent
(6)
- Tranquil island escape with complimentary airport shuttle and easy access to São Tomé.
The price is $21
$21
$76 total
includes taxes & fees
Dec 21 - Dec 22
Pestana São Tomé
Pestana São Tomé
5.0 star property
Vila Maria
8.0 out of 10, Very Good, (78)
8.0/10
Very Good
(78)
- Experience a tropical paradise at this beachfront hotel with fitness center and poolside bar.
The price is $201
$201
$236 total
includes taxes & fees
Dec 23 - Dec 24
Alojamento Santos Silva
Alojamento Santos Silva
3.0 star property
São Tomé
The price is $321
$321
$369 total
includes taxes & fees
Dec 25 - Dec 26
CAMPISMO PRAIA GRANDE
CAMPISMO PRAIA GRANDE
1.0 star property
Malanza
8.6 out of 10, Excellent, (4)
8.6/10
Excellent
(4)
- Experience beachside camping in Malanza with on-site water activities and free perks.
The price is $55
$55
$63 total
includes taxes & fees
Dec 22 - Dec 23
Pestana Miramar São Tomé
Pestana Miramar São Tomé
3.0 star property
São Tomé
7.2 out of 10, Good, (45)
7.2/10
Good
(45)
- Beach resort with international dining, poolside bar, and airport shuttle service.
The price is $146
$146
$172 total
includes taxes & fees
Dec 21 - Dec 22
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Guadalupe and vicinity
8.8 out of 10, Excellent, (6)
8.8/10
Excellent
(6)
The price is $21
$21
$76 total
includes taxes & fees
Dec 21 - Dec 22
8.6 out of 10, Excellent, (4)
8.6/10
Excellent
(4)
The price is $55
$55
$63 total
includes taxes & fees
Dec 22 - Dec 23
8.2 out of 10, Very Good, (24)
8.2/10
Very Good
(24)
The price is $56
$56
$65 total
includes taxes & fees
Dec 28 - Dec 29
10.0 out of 10, Exceptional, (1)
10/10
Exceptional
(1)
8.6 out of 10, Excellent, (10)
8.6/10
Excellent
(10)
10.0 out of 10, Exceptional, (3)
10/10
Exceptional
(3)
The price is $92
$92
$105 total
includes taxes & fees
Dec 21 - Dec 22
7.2 out of 10, Good, (45)
7.2/10
Good
(45)
The price is $146
$146
$172 total
includes taxes & fees
Dec 21 - Dec 22
7.2 out of 10, Good, (17)
7.2/10
Good
(17)
The price is $127
$127
$146 total
includes taxes & fees
Dec 25 - Dec 26
9.4 out of 10, Exceptional, (26)
9.4/10
Exceptional
(26)
The price is $136
$136
$156 total
includes taxes & fees
Dec 21 - Dec 22
7.6 out of 10, Good, (17)
7.6/10
Good
(17)
The price is $170
$170
$196 total
includes taxes & fees
Dec 21 - Dec 22
8.0 out of 10, Very Good, (78)
8.0/10
Very Good
(78)
The price is $201
$201
$236 total
includes taxes & fees
Dec 23 - Dec 24
9.4 out of 10, Exceptional, (62)
9.4/10
Exceptional
(62)
The price is $214
$214
$251 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Guadalupe
Learn more about Guadalupe
The region around Guadalupe is home to attractions such as São Sebastião Museum and Estadio Nacional 12 de Julho.
Photo by Fabrice Récalt
Open Photo by Fabrice Récalt
Check out reviews of Guadalupe hotels guests love
Pestana São Tomé
10/10 Excellent
"Wonderful stay, great staff, easy, relaxing delightful."
Omali São Tomé – Principe Collection
10/10 Excellent
"Staff was very friendly. Food was excellent. Room was clean and well kept."
Hotel Kriola
10/10 Excellent
"Loved the mermaids in the pool"
Porcelana Hotel
10/10 Excellent
"The place is great, water flows very well and you can get warm for your shower real quick. The hotel manager Leu was helpful and addressed any concerns I had. Again Sipson Tours was great with helping me navigate my accommodation. There is breakfast included and my best part is the fruit options which always part of the meal. The downside is that there is really no variety in the breakfast meal. However, overall I enjoyed my stay. "
Hotel Kenito
10/10 Excellent
"Exceptional"
CAMPISMO PRAIA GRANDE
10/10 Excellent
"A little piece of paradise on an amazing beach. "
Casa de Ferias
10/10 Excellent
"It's basic, but it's the best value on sao tome"
Frequently asked questions
What accommodations do travelers like in Guadalupe?
Guests like Residêncial Tamarindos, Pestana São Tomé and Hotel Central.
Can I book refundable hotels in Guadalupe?
If you need the flexibility to change your plans to Guadalupe, most properties provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Why should I book my Guadalupe hotel through Hotels.com?
There are lots of reasons to book your Guadalupe trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.