Hotels in Santiago

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Tonight
Sep 4 - Sep 5
Tomorrow
Sep 5 - Sep 6
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Where to stay in Santiago?

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.
A spacious lobby with modern seating, a central coffee table, and decorative hanging lights.
A restaurant with booths and tables, wooden paneling, and green plants.
A modern hotel with a prominent entrance, outdoor seating area, and a handicap-accessible parking space.

Hotel Mykonos Panama

Hotel Mykonos Panama
Nuevo Santiago
$90
$99 total
includes taxes & fees
Sep 5 - Sep 6
Hotel Mykonos Panama
A pool surrounded by palm trees and a tiled roof structure.
A tree in a stone planter in a well-lit indoor space with a stone wall and a door in the background.
A hallway with a glass partition leading to a dining area, a stone wall, and a metal gate with decorative patterns.
A spacious room with a high ceiling, a large window, and a wooden door leading to another area. There are several potted plants and a small table with a vase.

Hotel Gran David

Hotel Gran David
Santiago
$73
$80 total
includes taxes & fees
Sep 5 - Sep 6
Hotel Gran David
A swimming pool with a tiled deck, a covered seating area, and a multi-story building with balconies in the background.
An indoor sports court with blue flooring and glass walls.
A child sliding down a multi-colored slide into a ball pit filled with orange, blue, and white balls.
An outdoor seating area with tables and benches, a large screen, and a balloon decoration.

Hotel Plaza

Hotel Plaza
Nuevo Santiago
Hotel Plaza
A swimming pool with a gazebo, lounge chairs, and a tiled patio area.
A building with a swimming pool and a covered patio area.
A gym with treadmills, elliptical machines, and weightlifting equipment.
A spacious indoor area with wicker furniture, ceiling fans, and a balcony with a railing.

Hotel Galería

Hotel Galería
Nuevo Santiago
Hotel Galería
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.
A multi-story hotel with balconies, a pool, and a reflection in the water.
A spacious dining area with high ceilings, large windows, and natural light. Tables are set with chairs and centerpieces.
A hammock suspended between two white walls in a room with a balcony.

HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena
$77
$84 total
includes taxes & fees
Sep 6 - Sep 7
HOTEL VISTA LAGO
A hotel courtyard at night with a central pathway, palm trees, and well-lit buildings.
A group of people playing slot machines in a casino.
A bar area with wicker stools, a stone wall, and a variety of bottles and glasses on shelves.
A building entrance with a checkered floor, a central doorway, and a ceiling light.

Hotel La Hacienda

Hotel La Hacienda
Rodrigo Luque
Hotel La Hacienda
A room with two beds, a refrigerator, and a coat rack.
A view through a glass door of a patio area with a table and chairs, overlooking a lush garden and distant mountains.
Hotel Anachoreo with a corrugated metal roof, surrounded by tropical vegetation.

Hotel Anachoreo

Hotel Anachoreo
Santa Fe
$85
$93 total
includes taxes & fees
Sep 5 - Sep 6
Hotel Anachoreo
A resort with two buildings, a swimming pool, and lush greenery.
A covered outdoor seating area with two wooden tables and two wicker chairs, leading to a patio with a view of greenery.
A bed with a striped bedspread, a green pillow, and a painting of a forest scene on the wall.
A beach with palm trees and a vehicle parked on the sand.

Rainforest Yasmin Hotel

Rainforest Yasmin Hotel
Santa Fe
Rainforest Yasmin Hotel
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Our prices for hotels in Santiago are cheapest in December
Price trends for hotels in Santiago
Pricing is based on two traveler single night rates
View properties in September
Typical weather for Santiago
September
High 29°C / low 23°C. Rainy most days.
View properties in September
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Monthly weather averages (˚C)

Top landmarks in Santiago

Escuela Normal Juan Demostenes Arosemena

9.2/10 (9 reviews)
If you'd like to get a taste of Santiago student life, check out Escuela Normal Juan Demostenes Arosemena, in the heart of the town.
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Omar Torrijos Herrera Stadium

8.4/10 (9 reviews)
You can catch an event at Omar Torrijos Herrera Stadium, located 0.6 mi (1 km) from central Santiago.
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Catedral of Santiago Apostol

8.8/10 (13 reviews)
If you're planning a bit of sightseeing during your trip, head to Catedral of Santiago Apostol— just one of the monuments in central Santiago.
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Plaza Banconal

8.6/10 (12 reviews)
If you like shopping, take time out to go to Plaza Banconal when in Santiago.
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Learn more about Santiago

Santiago is well-known for its attractions such as Catedral of Santiago Apostol and Omar Torrijos Herrera Stadium. The city has something for everyone including restaurants along with sights like Plaza Banconal.

See all hotels in Santiago
A coastal archaeological site with ruins and boats on the water.

Check out reviews of Santiago hotels guests love

Hotel Gran David

Hotel Gran David

10/10 Excellent
"Although road side, this hotel is a gem. Old fashioned but well appointed. Staff were friendly and helpful. Included breakfast was good. Had a nice pool and gym."
David 1-night trip
Posted 5 days ago
Hotel Gran David
HOTEL VISTA LAGO

HOTEL VISTA LAGO

10/10 Excellent
"We had a very nice room with lake view, private terrace with hammock. Breakfast was very good too, pool and garden very nice and clean. Would always go back."
Hedwig 2-night trip
Posted 6 days ago
HOTEL VISTA LAGO
Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes

10/10 Excellent
"Excelente"
Olopilel 1-night trip
Posted 10 days ago
Hotel Plaza Los Tucanes
Hotel Mykonos Panama

Hotel Mykonos Panama

10/10 Excellent
"Very well located"
Ismael 1-night trip
Posted 1 month ago
Hotel Mykonos Panama
Hotel Galería

Hotel Galería

10/10 Excellent
"Hay un restaurante en el hotel con desayuno y comida económica y muy sabrosa. La ubicación del hotel es muy céntrica. Es seguro. Tiene centro comercial al lado. Parqueo de carro seguro. Es perfecto para una visita a Santiago."
Lionel 1-night trip
Posted 5 months ago
Hotel Galería

Frequently asked questions

What hotels do travelers like in Santiago?
Guests like Hotel Gran David, HOTEL CORPORATIVO PLAZA COROTÚ and HOTEL PLAZA COROTÚ.
Where can I get free parking at my hotel in Santiago?
HOTEL PLAZA COROTÚ offers the perk of free parking.
Can I book refundable hotels in Santiago?
If you need the flexibility to change your travel plans to Santiago, most hotels offer refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I consider staying in Santiago if I want a reasonably priced accommodation?
An inexpensive option worth considering is HOTEL PLAZA COROTÚ.
What will the weather in Santiago be like during my trip?
Santiago is a great place to visit any time of year with an average temperature of 77°F during the coldest months.
Why should I book my Santiago accommodation with Hotels.com?
There are lots of reasons to book your Santiago trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.