Hotels in San Isidro

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Mamacita's Guest House
Mamacita's Guest House
2.5 star property
Culebra Pueblo
8.0 out of 10, Very Good, (551 reviews)
Perfectly positioned for island adventures, this guesthouse offers easy access to Flamenco Beach. After exploring, return to enjoy local cuisine at Mamacitas Restaurant or sip drinks at the bar while savoring the views from the terrace.
The price is $126
$152 total
includes taxes & fees
May 5 - May 6
Mamacita's Guest House
El Navegante de Culebra
El Navegante de Culebra
3.0 star property
Culebra Pueblo
8.8 out of 10, Excellent, (369 reviews)
Wake up in tranquil Culebra, just minutes from the ferry terminal and pristine Flamenco Beach. This clean, well-situated hotel offers free WiFi, convenient minibars in every room, and complimentary parking for island explorations with attentive staff ready to assist.
The price is $137
$182 total
includes taxes & fees
Apr 29 - Apr 30
El Navegante de Culebra
Sea Gate Hotel
Sea Gate Hotel
2.5 star property
Isabel II
9.6 out of 10, Exceptional, (1,002 reviews)
The price is $110
$126 total
includes taxes & fees
Apr 28 - Apr 29
Sea Gate Hotel
Vieques Tropical Guest House
Vieques Tropical Guest House
2.0 star property
Isabel II
7.8 out of 10, Good, (80 reviews)
Experience tropical tranquility just a 15-minute drive from Vieques Ferry Terminal and the magical Bioluminescent Bay. This welcoming guesthouse provides free WiFi, complimentary parking, and a peaceful garden for ultimate relaxation during your Puerto Rican island retreat.
The price is $75
$139 total
includes taxes & fees
May 17 - May 18
Vieques Tropical Guest House
Old Crow Hotel and Suites
Old Crow Hotel and Suites
2.5 star property
Vieques
8.8 out of 10, Excellent, (228 reviews)
Immerse yourself in island life at this serene hotel just 15 minutes from the Bioluminescent Bay. Splash in the outdoor pool after exploring nearby attractions, then enjoy free WiFi and parking. Staff receive high marks from guests for their exceptional service.
The price is $99
$113 total
includes taxes & fees
Apr 28 - Apr 29
Old Crow Hotel and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What hotels do travelers like in San Isidro?
Can I book a refundable accommodation in San Isidro?
If you're looking for the flexibility to change your plans to San Isidro, most properties offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in San Isidro be like during my visit?
San Isidro is a great place to visit any time of year with an average temperature of 78°F during the coldest months.
Why should I book my San Isidro hotel through Hotels.com?
There are plenty of reasons to book your San Isidro travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.