Hotels in Panacea

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Sep 1 - Sep 2
Tomorrow
Sep 2 - Sep 3
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Top 5 hotels in Panacea at a glance

  1. The Panacea Motel — 2-star hotel in Panacea. Guest rating: 9.0/10 — Wonderful.
  2. Best Western Wakulla Inn & Suites — 2.5-star hotel in Crawfordville. Guest rating: 8.8/10 — Excellent.
  3. Wildwood Inn — 3-star hotel in Crawfordville. Guest rating: 8.6/10 — Excellent.
  4. The Lodge at Wakulla Springs — 3-star hotel in Crawfordville. Guest rating: 9.4/10 — Exceptional.
  5. St James Bay Golf & Pickleball Resort — 3.5-star hotel in Carrabelle. Guest rating: 9.0/10 — Wonderful.

Where to stay in Panacea?

The Panacea Motel

The Panacea Motel
Panacea
$119
$133 total
includes taxes & fees
Sep 2 - Sep 3
The Panacea Motel

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
Crawfordville
$111
$124 total
includes taxes & fees
Sep 23 - Sep 24
Best Western Wakulla Inn & Suites

Wildwood Inn

Wildwood Inn
Crawfordville
$120
$138 total
includes taxes & fees
Sep 23 - Sep 24
Wildwood Inn

The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
Crawfordville
$89
$100 total
includes taxes & fees
Sep 28 - Sep 29
The Lodge at Wakulla Springs

St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
Carrabelle
$118
$168 total
includes taxes & fees
Sep 2 - Sep 3
St James Bay Golf & Pickleball Resort

The Old Carrabelle Hotel

The Old Carrabelle Hotel
Carrabelle
$100
$110 total
includes taxes & fees
Sep 9 - Sep 10
The Old Carrabelle Hotel

The Moorings Hotel and Marina

The Moorings Hotel and Marina
Carrabelle
$138
$153 total
includes taxes & fees
Oct 1 - Oct 2
The Moorings Hotel and Marina

Franklin Inn

Franklin Inn
Carrabelle
$104
$115 total
includes taxes & fees
Sep 2 - Sep 3
Franklin Inn
View all properties
Our prices for hotels in Panacea are cheapest in February
Price trends for hotels in Panacea
Pricing is based on two traveler single night rates
View properties in September
Typical weather for Panacea
September
High 30°C / low 23°C. Sunny most days.
View properties in September
30°
23°
27°
18°
22°
13°
19°
11°
17°
19°
10°
22°
13°
25°
16°
29°
20°
31°
23°
32°
24°
32°
25°
Monthly weather averages (˚C)

Top landmarks in Panacea

Alligator Point Beach

8.8/10 (10 reviews)
When the beach is calling your name, you might want to head down to Alligator Point Beach, located 4.5 mi (7.2 km) from central Alligator Point. Enjoy the sunset by the shore at Wilson Beach.
See properties

Bald Point State Park

8.6/10 (20 reviews)
Bald Point State Park is 1.7 mi (2.7 km) from central Alligator Point, why not stop by during your stay.
See properties

Mashes Sand Beach

8.8/10 (3 reviews)
If being by the water is a major draw, Mashes Sand Beach is a spot you might want to check out, located 5.1 mi (8.2 km) from central Panacea. If you want to continue walking by the waves, head to Shell Point Beach, Wilson Beach, and Alligator Point Beach.
See properties

Wilson Beach

Whether you want to collect beach glass or watch the sunset, Wilson Beach is a spot you might want to check out, located 7.4 mi (11.9 km) from central Panacea. Enjoy the sunset by the shore at Alligator Point Beach.
See properties

beach near Summer Camp Beach

Whether you want to collect beach glass or watch the sunset, beach near Summer Camp Beach is a spot you might want to check out, located 10.3 mi (16.6 km) from central Panacea. If you want to continue walking by the waves, head to Wilson Beach and Alligator Point Beach.
See properties

beach near Alligator Point

When the beach is calling your name, you might want to head down to beach near Alligator Point, located 2.7 mi (4.4 km) from central Alligator Point. If you want to continue walking by the waves, head to Alligator Point Beach and Wilson Beach.
See properties

Panacea Springs

Panacea Springs is worth a visit, located 0.6 mi (1 km) from central Panacea.
See properties

Public Beach Access

Public Beach Access is 2.3 mi (3.7 km) from central Alligator Point, why not stop by during your stay. Want to stretch your legs some more? Head to Alligator Harbor Aquatic Preserve, located nearby.
See properties

Learn more about Panacea

Notable for its natural beauty, Panacea features attractions such as Mashes Sand Beach and Alligator Point Beach. This beachside city has something for everyone including seafood restaurants as well as sights like Bald Point State Park and Wilson Beach. All are within a secluded setting.

See all hotels in Panacea
A sunset over a calm body of water with silhouettes of birds flying and a distant tree line.

Check out reviews of Panacea hotels guests love

The Panacea Motel

The Panacea Motel

10/10 Excellent
"This was a cute little surprise right on the highway. We arrived pretty late, after 10 for sure but our room was ready and we were definitely ready for the place to rest."
Holly 1-night trip
Posted 3 days ago
The Panacea Motel

Frequently asked questions

What hotels do travelers like in Panacea?
Guests like The Panacea Motel.
Can I book a refundable accommodation in Panacea?
If you're looking for the flexibility to change your travel plans to Panacea, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Panacea if I want a vacation home instead of a traditional hotel?
If you want a good alternative to a hotel, browse our selection of 178 vacation homes. In addition, there are 18 apartments and 10 condos.
What will the weather in Panacea be like during my visit?
July and August are typically the warmest months in Panacea when the average temp is 81°F. January and February are the coldest months when the average temperature is 58°F. August and July are the months with the most rain.
Why should I book my Panacea hotel through Hotels.com?
There are lots of reasons to book your Panacea trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring