Hotels in Santa Clara

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A garden with a stream, a stone building, and a hanging planter.

A room with a wooden ceiling, a bed, a desk, a chair, and a TV.

A living room with a sofa, a coffee table, and a lamp.

A modern building with a stone facade, a central entrance with a triangular roof, and a parking area with several cars.

1. Hotel Dos Rios

Nueva California

$86

$94 total

includes taxes & fees

Oct 15 - Oct 16

An indoor swimming pool area with a wooden ceiling and glass walls, surrounded by plants and seating.

A serene park with a pond, fountains, and lush greenery.

A hotel with a red roof, multiple floors, and a fountain in the foreground.

A hotel room with a large bed, a desk, and chairs, a balcony with a view of greenery, and a brick wall.

2. Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

Volcan

$120

$132 total

includes taxes & fees

Nov 8 - Nov 9

A room with two beds, wooden beams on the ceiling, a stone wall, a window with curtains, and a bedside table with a lamp.

A bar area with a counter, bar stools, and a fireplace. There are leather sofas and a table with chairs.

A restaurant with a long table set for a meal, a bar with various bottles, and a television screen above the bar.

A building named "Los Brezos" with a parking area in front, surrounded by mountains and some vegetation.

3. Los Brezos Boutique Hotel

Volcan

$119

$131 total

includes taxes & fees

Oct 15 - Oct 16

A residential area with a well-maintained lawn, satellite dishes, and a white car parked in front of a yellow building.

A room with a wooden wardrobe, a desk with a chair, a small white appliance, a mirror, and a mounted television.

A room with a white door, a black TV mounted on the wall, a white standing fan, and various informational posters on the wall.

A bedroom with a wooden wardrobe, a television mounted on the wall, and a window with patterned curtains.

4. Hostal Victoria Volcán Chiriquí S. A.

Nueva California

$41

$45 total

includes taxes & fees

Oct 15 - Oct 16

A wooden cabin surrounded by dense forest.

A cozy interior with a fireplace, wooden furniture, and large windows.

A wooden-paneled bedroom with a large bed, two bedside lamps, and framed artwork on the walls.

A covered outdoor swimming pool with wooden benches and a view of a lush forest.

5. Los Quetzales Ecolodge & Spa

Cerro Punta

$108

$118 total

includes taxes & fees

Oct 15 - Oct 16

A living room with a sofa, armchair, and dining table.

A flat-screen TV mounted on a wall with a white shelf below it containing electronic devices and cables.

A single-story building with a flat roof, a front door, and a large window.

A bedroom with a bed, a nightstand, a wall-mounted cabinet, and a window with a floral curtain.

6. la casa de Matias

Volcán

$45

$49 total

includes taxes & fees

Oct 15 - Oct 16

A room with a dark-colored sofa set, a matching armchair, and a door with a light blue frame.

A flat-screen TV mounted on a wall with a white stand below it, connected to various electronic devices and cables.

A dining area with a rectangular table, four matching chairs, and a red patterned runner.

A single-bed room with a wooden headboard, a patterned bedspread, and a small bedside table with a lamp.

7. Urban Loft Nueva California

Nueva California

$41

$45 total

includes taxes & fees

Oct 15 - Oct 16

A spacious dining area with wooden beams and hanging light fixtures, large windows with views of greenery, and neatly arranged tables and chairs.

An aerial view of a large, two-story building with a green roof, surrounded by lush greenery and terraced fields.

An outdoor seating area with wicker chairs and a stone fireplace.

A rustic interior with a stone fireplace, wooden floors, and a bar area with stools.

8. Hotel Finca Lerida

Los Naranjos

$168

$184 total

includes taxes & fees

Oct 15 - Oct 16

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Check out reviews of Santa Clara hotels guests love

Los Brezos Boutique Hotel

8/10 Good

"Me encantó el hotel solo haría unos cambios en los ingredientes de la cocina pero me volvería a quedar la habitación cumple con toda la comodidad para la estancia Gracias"

la casa de Matias

8/10 Good

"The location on Google maps was very poor, we had to contact the owner because we couldn't find the house. In the house it would have been nice to have a closet to hang clothes, and some out door seating with a small table would be nice."

Hotel Finca Lerida

10/10 Excellent

"Todo muy rico y el lugar encantador"

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

10/10 Excellent

"Una buena propiedad para alejarse de todo y encontrarse con la naturaleza. Muy buen ambiente y hospitalidad. El personal se portó de maravillas, y fueron muy servicial. Tomé la opción de desayuno incluidos, y muy sabrosos. Me quedé 2 noches en Septiembre 2026. Regresaría de nuevo."

Hotel Dos Rios

10/10 Excellent

"Wonderful staff, property, and restaurant"

Wild on the Farm, Boquete Cloud Forest Lodge

10/10 Excellent

"Leon was very communicative throughout the booking. We STRONGLY recommend meeting Leon in the town for transportation or escort up to the lodge for initial arrival. It is a very steep climb. The path gets smaller as you go higher. There are no signs letting you know if you are on the right track. Our navigation told us we had arrived when we still had further to go. We rented a 4X4 in Panama City specifically for this booking. DO NOT UNDERESTIMATE the climb up to the location. It is very difficult for someone not familiar with the area."

Hostal Victoria Volcán Chiriquí S. A.

10/10 Excellent

"Room was clean. No breakfast served but coffee in the reception area where there are also breakfast snacks available for sale. The staff was amazing!"

Frequently asked questions

What hotels do travelers like in Santa Clara?

Guests like Hotel Dos Rios, Hostal Victoria Volcán Chiriquí S. A. and la casa de Matias.

Can I book a refundable hotel in Santa Clara?

If you're looking for the flexibility to change your plans to Santa Clara, most properties offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Santa Clara be like during my visit?

Santa Clara is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.

Why should I book my Santa Clara hotel through Hotels.com?

There are plenty of reasons to book your Santa Clara travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.