If museums are on your list of things to see, you might want to browse the collections at muZIEum in Stadscentrum. If you want to see more of the museums in Nijmegen, Valkhof Museum and Nationaal Fietsmuseum Velorama aren't far.
If you're planning a bit of sightseeing head to St Stevenskerk— just one of the monuments in Nijmegen-Centrum. You could also start your cultural experience by heading over to the museums in the area.