Hotels in Santa Cruz de la Sierra

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Check prices for these dates

Tonight
Apr 17 - Apr 18
Tomorrow
Apr 18 - Apr 19
This weekend
Apr 17 - Apr 19
Next weekend
Apr 24 - Apr 26

Where to stay in Santa Cruz de la Sierra?

Exterior
Finca El Azahar
Finca El Azahar
3.0 star property
Trujillo
10.0 out of 10, Exceptional, (7 reviews)
Escape to this tranquil Trujillo retreat featuring an inviting seasonal outdoor pool and its own winery. Enjoy complimentary breakfast, WiFi, and parking while discovering nearby hiking and biking trails.
The price is $231
$255 total
includes taxes & fees
Apr 27 - Apr 28
Finca El Azahar
Terrace/patio
Hospedium Hotel Soterraña
Hospedium Hotel Soterraña
3.0 star property
Madronera
8.8 out of 10, Excellent, (38 reviews)
This colonial hotel in Madronera offers a tranquil retreat with 2 restaurants and 2 bars/lounges. Unwind in the garden or terrace after exploring the area. Free WiFi and parking make your countryside escape in Spain convenient and stress-free.
The price is $75
$82 total
includes taxes & fees
Apr 21 - Apr 22
Hospedium Hotel Soterraña
Restaurant
Hostal León
Hostal León
2.0 star property
Trujillo
7.6 out of 10, Good, (53 reviews)
Experience authentic Spanish hospitality at this cozy hostal near Museo de Vino y Queso and Palace of the Dukes of San Carlos. Free WiFi keeps you connected while daily housekeeping ensures a fresh, comfortable atmosphere during your exploration of Trujillo's treasures.
The price is $59
$65 total
includes taxes & fees
May 5 - May 6
Hostal León
Breakfast, lunch, dinner served; Regional cuisine
Hostal Hueso
Hostal Hueso
2.0 star property
Trujillo
8.2 out of 10, Very Good, (24 reviews)
The price is $59
$65 total
includes taxes & fees
May 12 - May 13
Hostal Hueso
Interior
Plaza Sandra
Plaza Sandra
3.0 star property
Trujillo
9.6 out of 10, Exceptional, (53 reviews)
Escape to this tranquil retreat near Palace of the Dukes of San Carlos. Swim in the outdoor pool, unwind with a massage, or explore using free WiFi. Apartments feature convenient kitchens and sofa beds, plus a lovely terrace and garden for peaceful moments.
The price is $76
$84 total
includes taxes & fees
May 3 - May 4
Plaza Sandra
Ballroom
Hotel Izan Trujillo
Hotel Izan Trujillo
4.0 star property
Trujillo
8.8 out of 10, Excellent, (212 reviews)
Immerse yourself in Trujillo's rich culture at this hotel with El Refectorio restaurant serving authentic regional dishes. Swim in the seasonal outdoor pool, enjoy drinks at the bar, or relax on the terrace near Museo de Vino y Queso.
The price is $97
$106 total
includes taxes & fees
Apr 21 - Apr 22
Hotel Izan Trujillo
Exterior
Eurostars Palacio Santa Marta
Eurostars Palacio Santa Marta
4.0 star property
Trujillo
9.2 out of 10, Wonderful, (339 reviews)
Discover Spanish heritage in this historic hotel near Plaza Mayor and the Statue of Francisco Pizarro. Cool off in the outdoor pool, enjoy a drink at the bar, and savor meals at the restaurant. The helpful staff ensures a memorable stay in charming Trujillo.
The price is $84
$92 total
includes taxes & fees
May 17 - May 18
Eurostars Palacio Santa Marta
Exterior
Parador de Trujillo
Parador de Trujillo
4.0 star property
Trujillo
9.2 out of 10, Wonderful, (227 reviews)
This former palace boasts an outdoor pool where you can soak up the Spanish sun. Close to the Palace of the Dukes of San Carlos, the hotel offers a bar, garden, and café. Explore Trujillo's historic sites then unwind on the scenic terrace.
The price is $99
$109 total
includes taxes & fees
Apr 27 - Apr 28
Parador de Trujillo
Garden
Finca la Desa
Finca la Desa
3.0 star property
Miajadas
9.8 out of 10, Exceptional, (9 reviews)
The price is $80
$88 total
includes taxes & fees
Apr 19 - Apr 20
Finca la Desa
Restaurant
Casa Rural Las Canteras
Casa Rural Las Canteras
3.0 star property
Trujillo
8.2 out of 10, Very Good, (33 reviews)
A tranquil country house near historic Trujillo Castle and Pizarro House Museum. Relax with drinks at the bar or savor meals at the on-site restaurant. The outdoor terrace and garden offer peaceful moments after exploring nearby attractions, with free parking always available.
The price is $95
$105 total
includes taxes & fees
Apr 19 - Apr 20
Casa Rural Las Canteras
Apartment | Free WiFi, bed sheets
Hostal Ruralis Altozano
Hostal Ruralis Altozano
1.0 star property
Montánchez
9.0 out of 10, Wonderful, (2 reviews)
The price is $59
$65 total
includes taxes & fees
Apr 19 - Apr 20
Hostal Ruralis Altozano
Lunch and dinner served
Hospedium Hotel Triana
Hospedium Hotel Triana
3.0 star property
Miajadas
7.8 out of 10, Good, (19 reviews)
Escape to this Spanish hotel offering a restaurant and bar/lounge for relaxed dining. Enjoy complimentary WiFi and parking while the 24-hour front desk ensures around-the-clock assistance. A charming terrace and snack bar complete your countryside stay.
The price is $90
$99 total
includes taxes & fees
Apr 27 - Apr 28
Hospedium Hotel Triana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz de la Sierra

The region around Santa Cruz de la Sierra is home to attractions such as Juan Pizarro de Orellana Palace and Plaza Mayor.

See all hotels in Santa Cruz de la Sierra
Catedral de Santa Cruz de la Sierra

Check out reviews of Santa Cruz de la Sierra hotels guests love

Plaza Sandra

Plaza Sandra

10/10 Excellent
"Easy to follow check in instructions. Parking on the street nearby. Beautiful property right in the old town. Highly recommended!"
Ismael 1-night trip
Posted 7 days ago
Plaza Sandra

Frequently asked questions

What hotels do travelers recommend in Santa Cruz de la Sierra?
Guests like Eurostars Palacio Santa Marta, Parador de Trujillo and Hotel Izan Trujillo.
Can I book refundable hotels in Santa Cruz de la Sierra?
If you need the flexibility to change your plans to Santa Cruz de la Sierra, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Cruz de la Sierra be like during my trip?
July and August are typically the warmest months in Santa Cruz de la Sierra when the average temp is 77°F. January and February are the coldest months when the average temperature is 47°F. October and December are the months with the most rain.
Why should I book my Santa Cruz de la Sierra hotel through Hotels.com?
There are lots of reasons to book your Santa Cruz de la Sierra trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.