Hotels in Santa Ana

your current months are January, 2025 and February, 2025.
January 2025
February 2025

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Where to stay in Santa Ana?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santa Ana

Learn more about Santa Ana

The region around Santa Ana is home to attractions such as Nuestra Senora de Santa Ana and San Ignacio Miní.

Frequently asked questions

Can I book a refundable accommodation in Santa Ana?
If you’re looking for the flexibility to change your plans to Santa Ana, most hotels offer refundable* rates you can book. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Santa Ana be like during my visit?
The warmest months in Santa Ana are usually January and February with an average temp of 78°F. July and June are the chilliest months when the average temp is 62°F. The rainiest months are October and May.
Why should I book my Santa Ana hotel through Hotels.com?
There are plenty of reasons to book your Santa Ana travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.