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Hotels in Mesa

October 2026
7
November 2026

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This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Where to stay in Mesa?

A restaurant interior with wooden beams, antler decorations, and a long wooden bench.
A building with a porch, wooden steps, and two large wheels on the facade.
A bedroom with a wooden headboard, a bed with a green bedspread, two bedside tables with lamps, and a small wooden desk with a plant.
A bar area with wooden bar stools, a central bar counter, and shelves stocked with bottles and glasses.

1. Wagon Wheel Restaurant Bar and Motel

Wagon Wheel Restaurant Bar and Motel
Mesa
$170
$179 total
includes taxes & fees
Oct 11 - Oct 12
Wagon Wheel Restaurant Bar and Motel
A hotel with a swimming pool, lounge chairs, and a view of a mountain.
A house with a covered porch, a stone wall, and a mountain in the background.
A formal dining setting with a table set for four, including wine glasses and a vase of red roses.
A covered porch with white rocking chairs, a wooden barrel, and a view of a mountain.

2. Wine Country Inn Palisade

Wine Country Inn Palisade
Palisade
$152
$169 total
includes taxes & fees
Nov 1 - Nov 2
Wine Country Inn Palisade
Two people sitting on chairs outside a building with green doors, one holding a bottle.
A green door with the number 3, two brown chairs, and a potted plant.
A room with a sofa, a dining table, chairs, a potted plant, a wall-mounted plant, and a framed picture.
Two people sitting on a bed with a laptop and a book.

3. The Alpine Motel

The Alpine Motel
Collbran
$122
$131 total
includes taxes & fees
Oct 8 - Oct 9
The Alpine Motel
A rustic cabin with a garage, surrounded by a gravel driveway, a large tree with yellow leaves, and a rocky cliff in the background.
A modern bedroom with a large bed, a TV mounted on the wall, a bathroom with a shower curtain, and a small seating area with a chair.
A patio with a lounge chair and a table, a tree, and a view of the landscape.
A patio with two lounge chairs and a wooden table, overlooking a grassy area with autumn foliage and distant mountains.

4. The Homestead

The Homestead
Palisade
$207
$218 total
includes taxes & fees
Nov 1 - Nov 2
The Homestead
A sign for the Spoke and Vine Motel with a bicycle symbol, set against a mountainous backdrop.
A bar area with a bicycle wheel decoration, a bar menu, and shelves with bottles and snacks.
A metal cart with shelves holding mugs, a kettle, wine bottles, and fruit.
A dining area with a wooden table and chairs, a patterned rug, and pendant lighting.

5. Spoke and Vine Motel

Spoke and Vine Motel
Palisade
$152
$169 total
includes taxes & fees
Oct 27 - Oct 28
Spoke and Vine Motel
A wooden deck with a view of a forest and a lake.
A rustic interior with a wooden dining table, a striped armchair, a gray sofa, and a wooden cabinet.
A spacious restaurant with wooden tables and chairs, a chandelier, and a mural on the wall.
Two wooden cabins surrounded by a snowy forest.

6. Grand Mesa Lodge

Grand Mesa Lodge
Cedaredge
$122
$133 total
includes taxes & fees
Oct 11 - Oct 12
Grand Mesa Lodge
A wooden deck with a table and chairs, a stone wall, and a view of a lake surrounded by trees.
A room with a large window offering a view of a lake surrounded by trees.
A wooden cabin room with two beds, a small desk, and a stone archway.
A long wooden table with a polished surface, surrounded by chairs, in a rustic room with wooden walls and a brick fireplace.

7. Alexander lake lodge

Alexander lake lodge
Cedaredge
$113
$122 total
includes taxes & fees
Oct 21 - Oct 22
Alexander lake lodge
A spacious living area with a high ceiling, a wooden coffee table, a leather sofa, and a staircase leading to an upper level.
A spacious living room with a stone fireplace, a leather sofa, a desk with a computer, and a large mirror.
A hotel room with a large bed, a TV, a dresser, and a door.
An indoor swimming pool with clear water, a 3-foot depth marker, and a lifeguard stand.

8. Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites
Clifton
$110
$117 total
includes taxes & fees
Oct 26 - Oct 27
Best Western Grande River Inn & Suites
A rustic interior with a staircase, wooden beams, and potted plants.
A modern building with large windows, a staircase, and a solar panel.
A room with a bed, a desk, a chair, a table, and a view through a glass door to the outside.
A stone-floored patio with a bed, a chair, and a table.

9. Maison de Terre

Maison de Terre
Cedaredge
$140
$179 total
includes taxes & fees
Oct 11 - Oct 12
Maison de Terre
A parking lot with a red SUV, a blue truck, and a white car.
A gym with treadmills, weight machines, and exercise balls.
A hotel room with a bed, a desk, a television, and a window with curtains.
A reception area with a wooden counter, a coffee bar, and a large landscape painting on the wall.

10. Western Slope suites

Western Slope suites
Parachute
$72
$81 total
includes taxes & fees
Nov 1 - Nov 2
Western Slope suites
A reception desk at the Grand River Hotel with a stone wall backdrop and a large illuminated sign.
A cozy living room with a stone accent wall, leather sofa, patterned chairs, and horse-themed artwork.
A Grand River Hotel with a modern design, featuring a prominent entrance and a parking lot.
An indoor swimming pool with clear water, a red lounge chair, and a tiled floor.

11. Grand River Hotel

Grand River Hotel
Parachute
$65
$74 total
includes taxes & fees
Nov 1 - Nov 2
Grand River Hotel
A large indoor swimming pool with a hot tub, surrounded by lounge chairs and a tiled floor.
An outdoor patio with stone walls, wooden benches, and a fire pit.
A Grand Vista Hotel with a covered entrance, multiple windows, and a well-lit facade.
A hotel lobby with a reception desk, seating area, and fireplace.

12. Grand Vista Hotel Parachute

Grand Vista Hotel Parachute
Parachute
$84
$95 total
includes taxes & fees
Oct 8 - Oct 9
Grand Vista Hotel Parachute
A restaurant with stone walls and large windows, outdoor wooden tables and chairs, and a garden with colorful flowers.
A bar area with a wooden interior, bar stools, and a sign for Cook's Goldblume beer.
An indoor swimming pool with a mural of a desert landscape, a ceiling with skylights, and a seating area with chairs.
A dining area with a wooden table and chairs, a kitchen counter with various items, and a view of trees through large windows.

13. Grand Vista Hotel

Grand Vista Hotel
Horizon Drive District
$79
$91 total
includes taxes & fees
Nov 1 - Nov 2
Grand Vista Hotel
A spacious room with a large window, a red armchair, a wooden desk, and a lamp.
A reception desk with a wooden finish, a non-smoking sign, framed certificates on the wall, and a clock.
A hotel room with a bed, a desk with a computer, a mirror, a lamp, and a telephone.
A buffet area with a wooden counter, a glass display case, and a Coca-Cola machine.

14. Quality Inn Grand Junction near University

Quality Inn Grand Junction near University
Horizon Drive District
$64
$73 total
includes taxes & fees
Nov 4 - Nov 5
Quality Inn Grand Junction near University
A reception area with a wooden reception desk, a framed welcome sign, and a no-smoking sign.
A hotel room with two beds, a nightstand with a lamp, and two framed pictures on the wall.
A rectangular swimming pool with a blue tiled edge, surrounded by white lounge chairs and a metal fence.
A clean, modern dining area with a wooden counter and chairs.

15. Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado
Horizon Drive District
$60
$68 total
includes taxes & fees
Oct 18 - Oct 19
Super 8 by Wyndham Grand Junction Colorado
A reception desk with a clock, a computer, and a potted plant.
A modern office space with a desk, office chair, and a large landscape painting on the wall.
A modern living room with a fireplace, red leather chairs, a glass coffee table, and a large window with a mountain view.
A hotel hallway with a patterned carpet, doors on both sides, and a tiled ceiling.

16. Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction
Horizon Drive District
$68
$78 total
includes taxes & fees
Nov 1 - Nov 2
Ramada by Wyndham Grand Junction
Room
Living area
Interior
Living area

17. Camp Eddy

Camp Eddy
Pear Park
$61
$124 total
includes taxes & fees
Oct 18 - Oct 19
Camp Eddy
A bathroom with a large mirror, a sink, and a towel rack.
A reception area with a large mural of a desert landscape, two reception desks with modern design, and a patterned wall to the left.
A breakfast bar with a variety of food items, including fruits, pastries, and dairy products.
A hotel room with two beds, a desk, and a window with curtains.

18. La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction
Horizon Drive District
$98
$112 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Grand Junction
A spacious living area with a staircase, two grey armchairs, a round coffee table, and a view of the outside.
An indoor swimming pool with a lifeguard chair, pool ladder, and a seating area with tables and chairs.
A spacious dining area with multiple tables and chairs, a kitchen in the background, and a modern ceiling design.
A hotel room with a large bed, a desk, a chair, a small table, and a wall-mounted heater.

19. Comfort Inn Grand Junction I-70

Comfort Inn Grand Junction I-70
Horizon Drive District
$86
$99 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Inn Grand Junction I-70
A hotel entrance with a brick facade, a glass door, and a seating area with a table and chairs.
A modern kitchen with a wooden staircase, stainless steel countertops, and a built-in oven.
A bedroom with a large bed, a view of a vineyard, and a staircase.
A modern kitchen with wooden cabinetry, a black countertop, and a built-in oven.

20. Honey Rock Landing

Honey Rock Landing
Delta
$219
$237 total
includes taxes & fees
Nov 2 - Nov 3
Honey Rock Landing
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Go beyond your typical stay in Mesa

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Pet friendly
Pet friendly
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Hot tub
Hot tub
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Pool
Pool
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Spa
Spa
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Family friendly
Family friendly
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Apart­ment
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Cottage
Cottage
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Campsite
Campsite
Our prices for hotels in Mesa are cheapest in September

Price trends for hotels in Mesa

Pricing is based on two traveler single night rates
View properties in October

October

High 15°C / low 4°C. Sunny most days.
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Monthly weather averages (˚C)

Top landmarks in Mesa

Powderhorn Resort

8.6/10 (106 reviews)
Skiers and snowboarders might want to test out the slopes at Powderhorn Resort, a skiing spot located 6.7 mi (10.8 km) from central Mesa.
See properties

Learn more about Mesa

Mesa is well-known for its attractions such as Powderhorn Resort and Grand Mesa National Forest.

See all hotels in Mesa
A leafless tree on a rocky hillside with a vast landscape in the background.

Check out reviews of Mesa hotels guests love

A restaurant interior with wooden beams, antler decorations, and a long wooden bench.
A building with a porch, wooden steps, and two large wheels on the facade.
A bedroom with a wooden headboard, a bed with a green bedspread, two bedside tables with lamps, and a small wooden desk with a plant.
A bar area with wooden bar stools, a central bar counter, and shelves stocked with bottles and glasses.

Wagon Wheel Restaurant Bar and Motel

Wagon Wheel Restaurant Bar and Motel
Mesa

10/10 Exceptional

United States
Benjamin
Wagon Wheel Restaurant Bar and Motel
A rustic cabin with a garage, surrounded by a gravel driveway, a large tree with yellow leaves, and a rocky cliff in the background.
A modern bedroom with a large bed, a TV mounted on the wall, a bathroom with a shower curtain, and a small seating area with a chair.
A patio with a lounge chair and a table, a tree, and a view of the landscape.
A patio with two lounge chairs and a wooden table, overlooking a grassy area with autumn foliage and distant mountains.

The Homestead

The Homestead
Palisade

10/10 Exceptional

United States
Anne
The Homestead
A sign for the Spoke and Vine Motel with a bicycle symbol, set against a mountainous backdrop.
A bar area with a bicycle wheel decoration, a bar menu, and shelves with bottles and snacks.
A metal cart with shelves holding mugs, a kettle, wine bottles, and fruit.
A dining area with a wooden table and chairs, a patterned rug, and pendant lighting.

Spoke and Vine Motel

Spoke and Vine Motel
Palisade

10/10 Exceptional

United States
Robert
Spoke and Vine Motel
Two people sitting on chairs outside a building with green doors, one holding a bottle.
A green door with the number 3, two brown chairs, and a potted plant.
A room with a sofa, a dining table, chairs, a potted plant, a wall-mounted plant, and a framed picture.
Two people sitting on a bed with a laptop and a book.

The Alpine Motel

The Alpine Motel
Collbran

10/10 Exceptional

United States
Theresa
The Alpine Motel
A wooden deck with a table and chairs, a stone wall, and a view of a lake surrounded by trees.
A room with a large window offering a view of a lake surrounded by trees.
A wooden cabin room with two beds, a small desk, and a stone archway.
A long wooden table with a polished surface, surrounded by chairs, in a rustic room with wooden walls and a brick fireplace.

Alexander lake lodge

Alexander lake lodge
Cedaredge

10/10 Exceptional

United States
Richard
Alexander lake lodge
A rustic interior with a staircase, wooden beams, and potted plants.
A modern building with large windows, a staircase, and a solar panel.
A room with a bed, a desk, a chair, a table, and a view through a glass door to the outside.
A stone-floored patio with a bed, a chair, and a table.

Maison de Terre

Maison de Terre
Cedaredge

10/10 Exceptional

United States
Rosalind
Maison de Terre
A wooden deck with a view of a forest and a lake.
A rustic interior with a wooden dining table, a striped armchair, a gray sofa, and a wooden cabinet.
A spacious restaurant with wooden tables and chairs, a chandelier, and a mural on the wall.
Two wooden cabins surrounded by a snowy forest.

Grand Mesa Lodge

Grand Mesa Lodge
Cedaredge

10/10 Exceptional

United States
Amy
Grand Mesa Lodge
A spacious living area with a high ceiling, a wooden coffee table, a leather sofa, and a staircase leading to an upper level.
A spacious living room with a stone fireplace, a leather sofa, a desk with a computer, and a large mirror.
A hotel room with a large bed, a TV, a dresser, and a door.
An indoor swimming pool with clear water, a 3-foot depth marker, and a lifeguard stand.

Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites
Clifton

10/10 Exceptional

United States
Dana
Best Western Grande River Inn & Suites
An outdoor patio area with seating arrangements, tables, and umbrellas.
A modern restaurant with large windows offering a city view. Tables are set with dinnerware.
A modern living room with a sofa, a side table, a lamp, and a view of the city through large windows.
A modern bar area with a long counter, bar stools, and a view of the outdoors.

Hotel Maverick

Hotel Maverick
Capitol Hill

10/10 Exceptional

United States
Nate
Hotel Maverick
Room
Living area
Interior
Living area

Camp Eddy

Camp Eddy
Pear Park

10/10 Exceptional

United States
Matt
Camp Eddy
A living room with a fireplace, a television, and a shelf with decorative items.
A covered outdoor deck with a gazebo, a dining table with chairs, and a patio umbrella.
A bedroom with a large bed, a ceiling fan, a television, and a window with curtains.
A breakfast setting with a table set for two, including plates with food, glasses of orange juice, a pitcher, and a mug.

Castle Creek B&B

Castle Creek B&B
Grand Junction

10/10 Exceptional

United States
Keven
Castle Creek B&B
A parking lot with a red SUV, a blue truck, and a white car.
A gym with treadmills, weight machines, and exercise balls.
A hotel room with a bed, a desk, a television, and a window with curtains.
A reception area with a wooden counter, a coffee bar, and a large landscape painting on the wall.

Western Slope suites

Western Slope suites
Parachute

10/10 Exceptional

United States
Heather
Western Slope suites
An outdoor dining area with orange chairs and tables, a glass railing, and a view of the cityscape through large windows.
A modern hotel with a glass facade, outdoor seating area, and a visible logo.
A modern lounge area with blue and purple seating, round tables, and unique pendant lighting.
A breakfast station with yogurt and oatmeal dispensers, a coffee machine, and a sign advertising 'Top T Breakfast'.

Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown
Historic Grand Junction

10/10 Exceptional

United States
Anonymous traveler
Tru by Hilton Grand Junction Downtown
A hotel room with two beds, large windows, and a view of the street.
A red brick building with the year 1908 and the name 'MELROSE' on the facade.
A room with a dark blue wall, a round table, a pink velvet armchair, a sofa, and a chandelier.
A room with a glass table, a book, a lamp, and a mounted deer skull on the wall.

The Hotel Melrose

The Hotel Melrose
Historic Grand Junction

10/10 Exceptional

United States
Lisa
The Hotel Melrose
A bathroom with a large mirror, a sink, and a towel rack.
A reception area with a large mural of a desert landscape, two reception desks with modern design, and a patterned wall to the left.
A breakfast bar with a variety of food items, including fruits, pastries, and dairy products.
A hotel room with two beds, a desk, and a window with curtains.

La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction
Horizon Drive District

10/10 Exceptional

United States
Natalia
La Quinta Inn & Suites by Wyndham Grand Junction
A restaurant with stone walls and large windows, outdoor wooden tables and chairs, and a garden with colorful flowers.
A bar area with a wooden interior, bar stools, and a sign for Cook's Goldblume beer.
An indoor swimming pool with a mural of a desert landscape, a ceiling with skylights, and a seating area with chairs.
A dining area with a wooden table and chairs, a kitchen counter with various items, and a view of trees through large windows.

Grand Vista Hotel

Grand Vista Hotel
Horizon Drive District

10/10 Exceptional

United States
Chris
Grand Vista Hotel
A spacious living area with a staircase, two grey armchairs, a round coffee table, and a view of the outside.
An indoor swimming pool with a lifeguard chair, pool ladder, and a seating area with tables and chairs.
A spacious dining area with multiple tables and chairs, a kitchen in the background, and a modern ceiling design.
A hotel room with a large bed, a desk, a chair, a small table, and a wall-mounted heater.

Comfort Inn Grand Junction I-70

Comfort Inn Grand Junction I-70
Horizon Drive District

10/10 Exceptional

United States
Sandy
Comfort Inn Grand Junction I-70

Frequently Asked Questions

What accommodations do travelers like in Mesa?

Guests like Wagon Wheel Restaurant Bar and Motel and Powderhorn Lodging.

Can I book a refundable hotel in Mesa?

If you need the flexibility to change your travel plans to Mesa, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Mesa if I want a vacation home instead of a hotel?

Browse 10 vacation homes on our site. You can also book one of the 13 cabins for your stay.

What will the weather in Mesa be like during my vacation?

July and August are typically the warmest months in Mesa when the average temp is 69°F. January and December are the coldest months when the average temperature is 27°F. March and December are the months with the most rain.

Why should I book my Mesa hotel with Hotels.com?

There are lots of reasons to book your Mesa trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.