Hotels in Mayo

your current months are January, 2025 and February, 2025.
January 2025
February 2025

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Free cancellation options if plans change

Where to stay in Mayo?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mayo

Learn more about Mayo

Mayo is well-known for its attractions such as Suwannee River and Lafayette Blue Springs State Park.

Frequently asked questions

What accommodations do travelers recommend in Mayo?
Cindys Motel is a property that our guests really like.
Can I book refundable hotels in Mayo?
If you want the flexibility to change your travel plans to Mayo, most accommodations provide refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in Mayo if I want a vacation home instead of a traditional hotel?
You’ll find 7 vacation homes on our site.
What will the weather in Mayo be like during my vacation?
The warmest months in Mayo are usually July and August with an average temp of 80°F. January and February are the chilliest months when the average temp is 58°F. The rainiest months are June and August.
Why should I book my Mayo hotel with Hotels.com?
There are plenty of reasons to book your Mayo travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.