
Hotels in Louisiana
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River's Edge Motel
River's Edge Motel
2.0 star property
Louisiana
9.0 out of 10, Wonderful, (358)
9.0/10
Wonderful
(358)
cleanliness Enjoy a tranquil Louisiana getaway with river views and convenient amenities.
The price is $80
$80
$91 total
includes taxes & fees
Jan 1 - Jan 2, 2026




The Eagles Nest Inn
The Eagles Nest Inn
3.0 star property
Louisiana
9.4 out of 10, Exceptional, (19)
9.4/10
Exceptional
(19)
cleanliness Central Louisiana inn just steps from the Mississippi River with Italian dining.
The price is $96
$96
$109 total
includes taxes & fees
Jan 5 - Jan 6, 2026




Rodeway Inn Pittsfield
Rodeway Inn Pittsfield
2.0 star property
Pittsfield
6.8 out of 10, (127)
6.8/10
(127)
cleanliness Cozy Pittsfield retreat near local attractions with complimentary amenities.
The price is $62
$62
$68 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Green Acres Hotel
Green Acres Hotel
2.5 star property
Pittsfield
8.6 out of 10, Excellent, (141)
8.6/10
Excellent
(141)
cleanliness Charming countryside escape in Pittsfield with easy access to local attractions.
The price is $107
$107
$118 total
includes taxes & fees
Jan 1 - Jan 2, 2026




Monroe Street Suites
Monroe Street Suites
2.5 star property
Pittsfield
9.6 out of 10, Exceptional, (57)
9.6/10
Exceptional
(57)
cleanliness Wake up to small-town charm with modern conveniences in central Illinois.
The price is $86
$86
$95 total
includes taxes & fees
Jan 1 - Jan 2, 2026




William Watson Hotel
William Watson Hotel
3.0 star property
Pittsfield
9.2 out of 10, Wonderful, (348)
9.2/10
Wonderful
(348)
cleanliness Experience local charm at a historic hotel in downtown Pittsfield with fitness center.
The price is $85
$85
$93 total
includes taxes & fees
Jan 1 - Jan 2, 2026




Best Western On The River
Best Western On The River
2.5 star property
Hannibal
8.6 out of 10, Excellent, (1001)
8.6/10
Excellent
(1001)
cleanliness Make historic Hannibal adventures easy with pools, free breakfast, and riverfront access.
The price is $102
$102
$117 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Riverside Inn Hannibal
Riverside Inn Hannibal
2.5 star property
Hannibal
9.4 out of 10, Exceptional, (165)
9.4/10
Exceptional
(165)
cleanliness Experience classic riverside charm, minutes from Mark Twain's legacy.
The price is $182
$182
$244 total
includes taxes & fees
Jan 1 - Jan 2, 2026




Garden House Bed and Breakfast
Garden House Bed and Breakfast
2.0 star property
Hannibal
8.6 out of 10, Excellent, (38)
8.6/10
Excellent
(38)
cleanliness Relax near Hannibal's attractions with cozy beds and hiking trails nearby.
The price is $107
$107
$123 total
includes taxes & fees
Jan 3 - Jan 4, 2026




Motel 6 Hannibal, MO
Motel 6 Hannibal, MO
2.0 star property
Hannibal
7.4 out of 10, Good, (1000)
7.4/10
Good
(1000)
The price is $58
$58
$67 total
includes taxes & fees
Jan 14 - Jan 15, 2026




Howard Johnson BY Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
2.0 star property
Hannibal
7.2 out of 10, Good, (153)
7.2/10
Good
(153)
cleanliness Scenic riverside stay near Mark Twain sites with indoor pool and complimentary perks.
The price is $58
$58
$67 total
includes taxes & fees
Jan 3 - Jan 4, 2026




Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal
2.0 star property
Hannibal
7.4 out of 10, Good, (220)
7.4/10
Good
(220)
cleanliness Experience a warm welcome close to the Mississippi River in historic Hannibal.
The price is $68
$68
$78 total
includes taxes & fees
Jan 16 - Jan 17, 2026




Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
2.5 star property
Hannibal
7.6 out of 10, Good, (662)
7.6/10
Good
(662)
cleanliness Idyllic Missouri hotel near historic attractions with an indoor pool and spa.
The price is $76
$76
$90 total
includes taxes & fees
Jan 11 - Jan 12, 2026




Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
2.5 star property
Hannibal
6.4 out of 10, (737)
6.4/10
(737)
cleanliness Wake up to the Mississippi in this riverside hotel with an indoor pool and free hot breakfast.
The price is $59
$59
$68 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal
2.0 star property
Hannibal
7.2 out of 10, Good, (1001)
7.2/10
Good
(1001)
cleanliness Restful riverside getaway with outdoor pool and friendly staff awaits by the trails.
The price is $65
$65
$74 total
includes taxes & fees
Jan 16 - Jan 17, 2026




Lighthouse Inn & Suites
Lighthouse Inn & Suites
4.0 star property
Hannibal
8.8 out of 10, Excellent, (24)
8.8/10
Excellent
(24)
cleanliness Upgraded boutique aparthotel moments from Mississippi River and Molly Brown Museum.
The price is $188
$188
$215 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Quality Inn & Suites Hannibal West
Quality Inn & Suites Hannibal West
2.5 star property
Hannibal
8.0 out of 10, Very Good, (1004)
8.0/10
Very Good
(1004)
cleanliness Relax just 5 minutes from Historic Hannibal with indoor pool and free perks.
The price is $70
$70
$82 total
includes taxes & fees
Jan 11 - Jan 12, 2026




Sleep Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (1000)
9.6/10
Exceptional
(1000)
cleanliness Cozy Hannibal hotel offering indoor pool and free amenities near local attractions.
The price is $98
$98
$114 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Louisiana
Pet friendly
Family friendly
Learn more about Louisiana
Louisiana is hailed for its riverfront while attractions include Mississippi River.

Check out reviews of Louisiana hotels guests love

Super 8 by Wyndham Bowling Green
10/10 Excellent
"Welcoming staff for a holiday stay."

Quality Inn & Suites Hannibal West
10/10 Excellent
"Great hotel !!!!"

Sleep Inn & Suites Hannibal West
10/10 Excellent
"All of it perfect "

River's Edge Motel
10/10 Excellent
"Friendly and efficient check-in. Room was clean and fairly modern."

Howard Johnson BY Wyndham Hannibal
10/10 Excellent
"Great staff! Very friendly! "

Comfort Inn & Suites - Hannibal
10/10 Excellent
"The staff was very accommodating, very helpful with giving us dining places to go. Everyone was very friendly"

Best Western On The River
10/10 Excellent
"Nice place. "

Super 8 by Wyndham Hannibal
10/10 Excellent
"My stay was excellent staff very friendly and breakfast was always great "

Days Inn by Wyndham Hannibal
10/10 Excellent
"Great"
Frequently asked questions
What accommodations do travelers recommend in Louisiana?
River's Edge Motel is an accommodation that is popular with guests.
Can I book refundable accommodations in Louisiana?
If you want the flexibility to change your travel plans to Louisiana, most hotels provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Louisiana be like during my trip?
The warmest months in Louisiana are usually July and August with an average temp of 74°F. January and February are the chilliest months when the average temp is 35°F. The rainiest months are May and April.
Why should I book my Louisiana accommodation with Hotels.com?
There are plenty of reasons to book your Louisiana travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.