Hotels in St. Charles
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White Valley Motel
White Valley MotelSt. Charles
5.6 out of 10, (129 reviews)
cleanliness Cozy riverside motel in St. Charles with easy access to Whitewater River.
The price is $69
$77 total
includes taxes & fees
Feb 1 - Feb 2

Days Inn by Wyndham Winona
Days Inn by Wyndham WinonaWinona
7.8 out of 10, Good, (1,001 reviews)
cleanliness Modern Days Inn by the Mississippi with complimentary amenities and fitness.
The price is $68
$76 total
includes taxes & fees
Feb 2 - Feb 3

AmericInn by Wyndham Winona
AmericInn by Wyndham WinonaWinona
9.0 out of 10, Wonderful, (905 reviews)
cleanliness Stay minutes from Winona State University with hot tub and complimentary perks.
The price is $103
$115 total
includes taxes & fees
Feb 8 - Feb 9

The Wen Inn formerly Andor Wenneson
The Wen Inn formerly Andor WennesonPeterson
9.8 out of 10, Exceptional, (57 reviews)
cleanliness Escape to a charming inn adjacent to Peterson's golf course, with hiking trails nearby.
The price is $98
$107 total
includes taxes & fees
Feb 15 - Feb 16

Big River Escape Riverside Cabins
Big River Escape Riverside CabinsCochrane
9.2 out of 10, Wonderful, (42 reviews)
cleanliness Unwind in riverside cabins with kitchen convenience, just minutes from Mississippi River.
The price is $124
$130 total
includes taxes & fees
Feb 24 - Feb 25

Stone Mill Hotel & Suites
Stone Mill Hotel & SuitesLanesboro
9.2 out of 10, Wonderful, (664 reviews)
cleanliness Experience the serenity of countryside living at this golf-adjacent retreat in Lanesboro.
The price is $105
$113 total
includes taxes & fees
Feb 1 - Feb 2

Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGRochester
8.8 out of 10, Excellent, (1,002 reviews)
cleanliness Modern rooms near Mayo Clinic with indoor pool and free hot breakfast daily.
The price is $69
$79 total
includes taxes & fees
Feb 6 - Feb 7

Spark by Hilton Rochester South
Spark by Hilton Rochester SouthRochester
9.4 out of 10, Exceptional, (366 reviews)
cleanliness Cozy lodging near Mayo Clinic with complimentary breakfast and indoor pool access.
The price is $71
$81 total
includes taxes & fees
Feb 8 - Feb 9

Hampton Inn Rochester-South
Hampton Inn Rochester-SouthRochester
9.0 out of 10, Wonderful, (1,006 reviews)
cleanliness Peaceful hotel near Mayo Clinic with indoor pool and daily complimentary breakfast.
The price is $82
$95 total
includes taxes & fees
Feb 22 - Feb 23

Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic AreaRochester
9.0 out of 10, Wonderful, (929 reviews)
cleanliness Restful retreat near Mayo Clinic with 24-hour fitness center and complimentary perks.
The price is $63
$72 total
includes taxes & fees
Feb 13 - Feb 14

Big River Escape Parkside Bungalow
Big River Escape Parkside BungalowWinona
10.0 out of 10, Exceptional, (1 review)
cleanliness Quiet cottage retreat near Winona Station with free WiFi and parking.
The price is $206
$230 total
includes taxes & fees
Feb 3 - Feb 4

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic SRochester
7.2 out of 10, Good, (1,031 reviews)
cleanliness Convenient location near Mayo Clinic with free daily breakfast and on-site fitness.
The price is $72
$83 total
includes taxes & fees
Feb 1 - Feb 2

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHGDowntown Rochester
8.8 out of 10, Excellent, (924 reviews)
cleanliness Relax in quiet comfort with Mayo Clinic just a 15-minute walk away from this hotel.
The price is $99
$114 total
includes taxes & fees
Feb 21 - Feb 22

Quality Inn & Suites Mayo Clinic Area
Quality Inn & Suites Mayo Clinic AreaRochester
8.8 out of 10, Excellent, (845 reviews)
cleanliness Quiet refuge in Rochester's medical district with free hot breakfast daily.
The price is $64
$74 total
includes taxes & fees
Feb 14 - Feb 15

Hilton Garden Inn Rochester Downtown, MN
Hilton Garden Inn Rochester Downtown, MNDowntown Rochester
8.8 out of 10, Excellent, (869 reviews)
cleanliness A welcoming downtown haven near Mayo Clinic with indoor pool and hot tub.
The price is $107
$123 total
includes taxes & fees
Feb 6 - Feb 7

Baymont by Wyndham Rochester Mayo Clinic Area
Baymont by Wyndham Rochester Mayo Clinic AreaRochester
7.0 out of 10, Good, (733 reviews)
The price is $60
$69 total
includes taxes & fees
Feb 5 - Feb 6

Country Inn & Suites Rochester South Mayo Clinic
Country Inn & Suites Rochester South Mayo ClinicRochester
8.4 out of 10, Very Good, (1,002 reviews)
cleanliness A peaceful Mayo Clinic escape with complimentary hot breakfast and tranquil pool area.
The price is $84
$97 total
includes taxes & fees
Feb 22 - Feb 23

AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo ClinicRochester
8.0 out of 10, Very Good, (1,197 reviews)
cleanliness Peaceful retreat near Mayo Clinic with serene atmosphere and indoor pool.
The price is $74
$85 total
includes taxes & fees
Feb 22 - Feb 23

Birch Hill Suite Rochester – Med City
Birch Hill Suite Rochester – Med CityRochester
7.6 out of 10, Good, (12 reviews)
cleanliness Stylish retreat close to Mayo Clinic with thoughtful traveler amenities.
The price is $54
$63 total
includes taxes & fees
Feb 8 - Feb 9

MainStay Suites Rochester South Mayo Clinic
MainStay Suites Rochester South Mayo ClinicRochester
7.0 out of 10, Good, (94 reviews)
cleanliness Wake up just minutes from Mayo Clinic in comfort at this all-suite Rochester hotel.
The price is $56
$64 total
includes taxes & fees
Feb 1 - Feb 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in St. Charles
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Learn more about St. Charles
St. Charles is well-known for its attractions such as Whitewater State Park and Whitewater River.

Check out reviews of St. Charles hotels guests love

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
10/10 Excellent




































































