Hotels in Effingham

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Quality Inn Mullins - Marion
Quality Inn Mullins - Marion
2.5 star property
Marion
7.8 out of 10, Good, (394 reviews)
  • cleanliness
    Relax in a Marion hotel offering free breakfast and parking near Florence Regional.
The price is $98
$107 total
includes taxes & fees
Apr 24 - Apr 25
Quality Inn Mullins - Marion
Holiday Inn Express & Suites Latta by IHG
Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.6 out of 10, Exceptional, (568 reviews)
  • cleanliness
    Seasonal pool and free breakfast add value to your Florence-adjacent stay.
The price is $118
$129 total
includes taxes & fees
Apr 6 - Apr 7
Holiday Inn Express & Suites Latta by IHG
Best Western Executive Inn
Best Western Executive Inn
2.5 star property
Latta
8.2 out of 10, Very Good, (973 reviews)
  • cleanliness
    Quiet retreat with pool access in Latta, just 22 minutes from Florence Regional.
The price is $106
$116 total
includes taxes & fees
Apr 5 - Apr 6
Best Western Executive Inn
The Inn at the Crossroads
The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (866 reviews)
  • cleanliness
    Enjoy Lake City Bistro while staying minutes from Lynches Lake and The Bean Market.
The price is $183
$206 total
includes taxes & fees
Mar 29 - Mar 30
The Inn at the Crossroads
Quality Inn & Suites Lake City
Quality Inn & Suites Lake City
2.5 star property
Lake City
7.2 out of 10, Good, (171 reviews)
  • cleanliness
    Peaceful retreat with fitness center, free breakfast, and nearby lake attractions.
The price is $115
$129 total
includes taxes & fees
Apr 12 - Apr 13
Quality Inn & Suites Lake City
Days Inn by Wyndham Lake City
Days Inn by Wyndham Lake City
2.0 star property
Lake City
6.4 out of 10, (251 reviews)
  • cleanliness
    Lakeside motel with seasonal pool just minutes from local attractions.
The price is $109
$122 total
includes taxes & fees
Apr 6 - Apr 7
Days Inn by Wyndham Lake City
Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Stay comfortably near Florence attractions with an outdoor pool and 24-hour fitness center.
The price is $122
$137 total
includes taxes & fees
Apr 5 - Apr 6
Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton
Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (623 reviews)
  • cleanliness
    Take in serene surroundings at this spa hotel near Florence Station.
The price is $130
$146 total
includes taxes & fees
Apr 5 - Apr 6
Hotel Florence, Tapestry Collection by Hilton
Rodeway Inn Florence Downtown
Rodeway Inn Florence Downtown
2.0 star property
Florence
4.8 out of 10, (3 reviews)
  • cleanliness
    Experience Florence's downtown convenience in a hotel near local attractions.
The price is $55
$63 total
includes taxes & fees
Apr 26 - Apr 27
Rodeway Inn Florence Downtown
Super 8 by Wyndham Florence
Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1,001 reviews)
  • cleanliness
    Just outside Florence's center with easy highway access and a seasonal pool.
The price is $58
$65 total
includes taxes & fees
Apr 5 - Apr 6
Super 8 by Wyndham Florence
Clarion Inn & Suites Florence - Darlington
Clarion Inn & Suites Florence - Darlington
2.5 star property
Florence
4.4 out of 10, (315 reviews)
  • cleanliness
    Discover a comfortable stay near Darlington Raceway with pool and fitness center.
The price is $63
$71 total
includes taxes & fees
Apr 27 - Apr 28
Clarion Inn & Suites Florence - Darlington
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Set among lush landscapes, this Florence hotel offers easy interstate access and relaxing poolside comfort.
The price is $131
$147 total
includes taxes & fees
Apr 12 - Apr 13
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Best Western Inn
Best Western Inn
2.5 star property
Florence
7.8 out of 10, Good, (1,000 reviews)
  • cleanliness
    Restful stay in this well-located Florence hotel with helpful, attentive staff.
The price is $99
$111 total
includes taxes & fees
Mar 29 - Mar 30
Best Western Inn
MainStay Suites Florence - Darlington
MainStay Suites Florence - Darlington
2.5 star property
Florence
3.8 out of 10, (83 reviews)
  • cleanliness
    Step into modern comfort in Florence, just 10 minutes from the regional airport.
The price is $76
$85 total
includes taxes & fees
Apr 26 - Apr 27
MainStay Suites Florence - Darlington
Suburban Studios Florence I-95
Suburban Studios Florence I-95
2.0 star property
Florence
5.6 out of 10, (592 reviews)
  • cleanliness
    Stay minutes from Darlington Raceway in a convenient spot with easy I-95 access.
The price is $51
$58 total
includes taxes & fees
Apr 27 - Apr 28
Suburban Studios Florence I-95
Econo Lodge Florence - Darlington
Econo Lodge Florence - Darlington
2.0 star property
Florence
5.8 out of 10, (1,003 reviews)
  • cleanliness
    Experience NASCAR country with a simple stay just 15 minutes from Darlington Raceway.
The price is $53
$59 total
includes taxes & fees
Mar 29 - Mar 30
Econo Lodge Florence - Darlington
Studio 6 Florence , SC
Studio 6 Florence , SC
2.5 star property
Florence
3.4 out of 10, (6 reviews)
The price is $55
$62 total
includes taxes & fees
Mar 29 - Mar 30
Studio 6 Florence , SC
Motel 6 Florence, SC
Motel 6 Florence, SC
2.0 star property
Florence
6.2 out of 10, (672 reviews)
  • cleanliness
    Unwind in Florence with free WiFi and self-parking near top attractions.
The price is $60
$67 total
includes taxes & fees
Mar 29 - Mar 30
Motel 6 Florence, SC
Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very Good, (58 reviews)
The price is $89
$104 total
includes taxes & fees
Apr 7 - Apr 8
Spark by Hilton Florence North I-95, SC
La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,633 reviews)
  • cleanliness
    Experience comfort near highways and popular dining spots in peaceful Florence.
The price is $104
$117 total
includes taxes & fees
Apr 22 - Apr 23
La Quinta Inn & Suites by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What accommodations do travelers like in Effingham?
Can I book refundable accommodations in Effingham?
If you need the flexibility to change your plans to Effingham, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Effingham be like during my trip?
July and August are typically the warmest months in Effingham when the average temp is 78°F. January and February are the coldest months when the average temperature is 50°F. August and July are the months with the most rain.
Why should I book my Effingham accommodation with Hotels.com?
There are lots of reasons to book your Effingham trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.