Hotels in Santa Cruz Tlaxcala

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Hotel Ex hacienda Chautla Puebla, Trademark by Wyndham
Hotel Ex hacienda Chautla Puebla, Trademark by Wyndham
3.5 star property
San Salvador el Verde
8.6 out of 10, Excellent, (782 reviews)
The price is $145
$173 total
includes taxes & fees
May 18 - May 19
Hotel Ex hacienda Chautla Puebla, Trademark by Wyndham
Holiday Inn Tlaxcala by IHG
Holiday Inn Tlaxcala by IHG
3.5 star property
Yauhquemehcan
9.6 out of 10, Exceptional, (265 reviews)
Tucked into central Mexico, this hotel offers a rejuvenating spa experience with hot stone massages and reflexology. Enjoy international cuisine at Mayana restaurant and unwind in the indoor pool after exploring nearby Basilica of Ocotlan.
The price is $115
$136 total
includes taxes & fees
May 8 - May 9
Holiday Inn Tlaxcala by IHG
Hotel del Angel, Apizaco
Hotel del Angel, Apizaco
3.5 star property
San Martin de Porres
8.8 out of 10, Excellent, (289 reviews)
Warm sanctuary in Apizaco with a refreshing indoor pool for year-round relaxation. Grab international cuisine at Los Candiles restaurant, then unwind in the sauna after a workout in the fitness center. The bar offers perfect evening downtime with free parking.
The price is $103
$121 total
includes taxes & fees
May 3 - May 4
Hotel del Angel, Apizaco
Holiday Inn Express Puebla by IHG
Holiday Inn Express Puebla by IHG
3.5 star property
Puebla
9.4 out of 10, Exceptional, (1,817 reviews)
Enjoy complimentary breakfast before exploring Puebla's historic center, just a short drive away. After sightseeing at nearby Puebla Cathedral, unwind in the indoor pool or visit the 24-hour fitness center. The tourist train terminal is only minutes from this convenient hotel.
The price is $59
$70 total
includes taxes & fees
May 10 - May 11
Holiday Inn Express Puebla by IHG
City Express by Marriott Apizaco
City Express by Marriott Apizaco
3.0 star property
Apizaco
9.2 out of 10, Wonderful, (425 reviews)
Wake up to complimentary continental breakfast at this contemporary Marriott hotel in Apizaco. Enjoy the fitness center after exploring the city via the free area shuttle. Just 52 minutes from Puebla International Airport with convenient amenities for business or leisure travelers.
The price is $75
$89 total
includes taxes & fees
May 4 - May 5
City Express by Marriott Apizaco
Hotel 1904
Hotel 1904
3.0 star property
Apizaco
8.0 out of 10, Very Good, (97 reviews)
Housed in a historic building dating back to 1904, this charming Apizaco hotel offers a restaurant and bar/lounge for relaxing evenings. Enjoy convenient perks including free WiFi and parking, just 39 minutes from Puebla Airport.
The price is $52
$62 total
includes taxes & fees
May 3 - May 4
Hotel 1904
Camino Real Puebla Angelopolis
Camino Real Puebla Angelopolis
4.0 star property
Angelópolis
8.2 out of 10, Very Good, (2,279 reviews)
This hotel in San Andrés Cholula offers international cuisine at La Huerta restaurant, a poolside bar, and fitness center. Just a short drive from Angelopolis Commercial Center and Zócalo de Puebla, guests love the helpful staff and convenient location.
The price is $62
$74 total
includes taxes & fees
Jun 1 - Jun 2
Camino Real Puebla Angelopolis
NH Puebla Centro Histórico
NH Puebla Centro Histórico
4.0 star property
Puebla Historic Center
8.6 out of 10, Excellent, (1,561 reviews)
Discover the heart of Puebla at this centrally located hotel, just a 10-minute walk from Zócalo de Puebla and the magnificent cathedral. Relax in the outdoor pool, energize at the 24-hour fitness center, or enjoy drinks at the bar.
The price is $65
$77 total
includes taxes & fees
May 9 - May 10
NH Puebla Centro Histórico
Hotel San Francisco Tlaxcala
Hotel San Francisco Tlaxcala
3.5 star property
Tlaxcala
9.0 out of 10, Wonderful, (442 reviews)
Mexican charm awaits at this Tlaxcala hotel with 2 restaurants and poolside bar. Rejuvenate with hot stone massages after exploring the nearby Art Museum of Tlaxcala or Museo de la Memoria. Free breakfast, WiFi, and parking enhance your authentic cultural experience.
Hotel San Francisco Tlaxcala
La Quinta by Wyndham Puebla Palmas Angelopolis
La Quinta by Wyndham Puebla Palmas Angelopolis
3.0 star property
Angelópolis
8.8 out of 10, Excellent, (1,496 reviews)
Immerse yourself in Art Deco elegance at this San Andrés Cholula retreat. Just a short drive from Angelopolis Commercial Center and Zócalo de Puebla, the hotel offers an indoor pool, fitness center, and bar/lounge, plus free breakfast, WiFi, and parking.
La Quinta by Wyndham Puebla Palmas Angelopolis
Four Points By Sheraton Puebla
Four Points By Sheraton Puebla
3.5 star property
Puebla
9.4 out of 10, Exceptional, (1,289 reviews)
Contemporary comfort in Puebla with an outdoor pool, fitness center, and María Ofelia restaurant serving international cuisine. Free WiFi and parking make this central spot perfect for exploring Zócalo and Puebla Cathedral while enjoying attentive staff service.
The price is $57
$68 total
includes taxes & fees
May 10 - May 11
Four Points By Sheraton Puebla
Courtyard by Marriott Puebla Las Animas
Courtyard by Marriott Puebla Las Animas
4.0 star property
Puebla
8.6 out of 10, Excellent, (1,034 reviews)
This Marriott hotel offers an outdoor pool, fitness center, and on-site dining at Courtyard Cafe serving local cuisine. Located near Angelopolis Commercial Center and Zócalo de Puebla, it features clean rooms and a welcoming terrace.
The price is $62
$74 total
includes taxes & fees
May 8 - May 9
Courtyard by Marriott Puebla Las Animas
Radisson Puebla Angelopolis
Radisson Puebla Angelopolis
4.5 star property
Angelópolis
9.0 out of 10, Wonderful, (483 reviews)
Located minutes from Angelopolis Commercial Center and Puebla Cathedral, this luxury hotel offers 2 restaurants serving international cuisine. Unwind with hot stone massages at the spa or relax at the bar after exploring nearby Zócalo de Puebla.
The price is $62
$74 total
includes taxes & fees
May 7 - May 8
Radisson Puebla Angelopolis
Hotel La Posada
Hotel La Posada
3.0 star property
Apizaco
8.0 out of 10, Very Good, (71 reviews)
Unwind at this business-friendly hotel offering 2 international restaurants and a welcoming bar/lounge. Work out in the fitness center or relax in the garden. Convenient perks include free WiFi and parking, just 48 minutes from Puebla Airport.
The price is $58
$68 total
includes taxes & fees
May 23 - May 24
Hotel La Posada
Grand Fiesta Americana Puebla Angelópolis
Grand Fiesta Americana Puebla Angelópolis
5.0 star property
Angelópolis
9.6 out of 10, Exceptional, (1,004 reviews)
Immerse yourself in international cuisine at La Distral after a relaxing spa day with deep-tissue massages and facials. Just a short drive from Zócalo de Puebla, this hotel offers 2 bars, a poolside lounge, and an outdoor pool.
The price is $140
$167 total
includes taxes & fees
May 26 - May 27
Grand Fiesta Americana Puebla Angelópolis
Fiesta Inn Parque Puebla
Fiesta Inn Parque Puebla
3.5 star property
Puebla
9.4 out of 10, Exceptional, (894 reviews)
Immerse yourself in comfort at this well-appointed Puebla hotel with an indoor pool and fitness center. Grab drinks at the bar or meals at the on-site restaurant with 24-hour room service. Located near Cuauhtemoc Stadium and Zócalo de Puebla.
The price is $88
$105 total
includes taxes & fees
Jun 1 - Jun 2
Fiesta Inn Parque Puebla
Ramada Encore by Wyndham Puebla
Ramada Encore by Wyndham Puebla
4.0 star property
Coronango
9.2 out of 10, Wonderful, (1,000 reviews)
Located in Coronango, this hotel offers easy access to the Great Pyramid of Cholula and Cuauhtemoc Stadium. Enjoy the indoor pool, fitness center, and international cuisine at The Hub restaurant. With free breakfast, WiFi, and parking, guests particularly praise the helpful staff.
The price is $68
$81 total
includes taxes & fees
May 2 - May 3
Ramada Encore by Wyndham Puebla
Holiday Inn Puebla La Noria by IHG
Holiday Inn Puebla La Noria by IHG
3.5 star property
La Noria
9.2 out of 10, Wonderful, (1,060 reviews)
Relax at this Mexican-inspired hotel with direct access to Puebla's top attractions. The fitness center and Terrae restaurant serving local cuisine create a welcoming atmosphere, while free WiFi and parking enhance your stay near Puebla Cathedral.
The price is $58
$69 total
includes taxes & fees
Jun 1 - Jun 2
Holiday Inn Puebla La Noria by IHG
Hotel Gilfer Puebla Centro Histórico
Hotel Gilfer Puebla Centro Histórico
4.0 star property
Puebla Historic Center
8.4 out of 10, Very Good, (680 reviews)
Immerse yourself in central Puebla at this welcoming hotel, just a 10-minute walk from the historic Zócalo and Cathedral. Savor international cuisine at 2 on-site restaurants while enjoying free WiFi throughout your stay.
The price is $69
$82 total
includes taxes & fees
May 3 - May 4
Hotel Gilfer Puebla Centro Histórico
Hilton Garden Inn Puebla Angelópolis, Mexico
Hilton Garden Inn Puebla Angelópolis, Mexico
3.5 star property
Angelópolis
9.2 out of 10, Wonderful, (1,002 reviews)
Wake up to mountain views at this hotel in San Andrés Cholula. Just a 10-minute drive from Angelopolis Commercial Center and Zócalo de Puebla, you'll enjoy an outdoor pool and fitness center after exploring. Unwind at the bar or grab a bite at the on-site restaurant.
The price is $68
$81 total
includes taxes & fees
May 10 - May 11
Hilton Garden Inn Puebla Angelópolis, Mexico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What hotels do travelers recommend in Santa Cruz Tlaxcala?
Can I book refundable hotels in Santa Cruz Tlaxcala?
If you want the flexibility to change your plans to Santa Cruz Tlaxcala, most accommodations provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where should I consider staying in Santa Cruz Tlaxcala if I want a reasonably priced accommodation?
Centro Vacacional IMSS La Trinidad is an accommodation you might want to consider that'll save you money.
What will the weather in Santa Cruz Tlaxcala be like during my vacation?
The warmest months in Santa Cruz Tlaxcala are usually April and May with an average temp of 61°F. January and December are the chilliest months when the average temp is 54°F. The rainiest months are August and September.
Why should I book my Santa Cruz Tlaxcala hotel with Hotels.com?
There are plenty of reasons to book your Santa Cruz Tlaxcala travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.