Hotels in Clarksdale

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Top 5 hotels in Clarksdale at a glance

Drury Inn & Suites St Joseph — 3-star hotel in St. Joseph. Guest rating: 9.4/10 — Exceptional.
Hampton Inn St. Joseph — 2.5-star hotel in St. Joseph. Guest rating: 8.2/10 — Very Good.
Holiday Inn Express Hotel & Suites St. Joseph by IHG — 2.5-star hotel in St. Joseph. Guest rating: 9.2/10 — Wonderful.
Fairfield Inn & Suites by Marriott St. Joseph — 3-star hotel in St. Joseph. Guest rating: 9.6/10 — Exceptional.
Stoney Creek Hotel St. Joseph — 3.5-star hotel in St. Joseph. Guest rating: 9.2/10 — Wonderful.

Where to stay in Clarksdale?

A lobby with a seating area, a reception desk, and a chandelier.

A hotel room with a kitchenette, a sofa, a bench, a lamp, and a framed picture on the wall.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

A hotel lobby with a reception desk, seating area, and a refrigerator.

Drury Inn & Suites St Joseph

St. Joseph

$110

$127 total

includes taxes & fees

Aug 30 - Aug 31

An indoor swimming pool with clear lane markings, a lifeguard chair, and a pool ladder.

A Hampton Inn by Hilton building with a modern facade, large windows, and a well-lit entrance.

A reception desk with a clock, a framed picture, and a wall with a 'smile' sign.

A snack and beverage vending area with various snack options and refrigerated beverage dispensers.

Hampton Inn St. Joseph

St. Joseph

$93

$108 total

includes taxes & fees

Aug 30 - Aug 31

A buffet with labeled food stations including omelets and cheese.

A hotel room with a bed, a sofa, a small table, a microwave, and a TV.

A Holiday Inn Express building with a stone facade, large windows, and a covered entrance area.

A hotel lobby with a green sofa, yellow armchairs, a patterned carpet, and a reception desk.

Holiday Inn Express Hotel & Suites St. Joseph by IHG

St. Joseph

$101

$117 total

includes taxes & fees

Aug 23 - Aug 24

A modern living room with a blue sofa, a fireplace, and a stone accent wall.

A Fairfield Inn & Suites Marriott hotel entrance with a modern design, including a prominent overhang and a stone pillar.

A restaurant with a long wooden table, chairs, and a bar area.

A modern hotel lobby with a stone fireplace, blue sofas, a round table, and large windows offering a view of the parking lot.

Fairfield Inn & Suites by Marriott St. Joseph

St. Joseph

$105

$122 total

includes taxes & fees

Aug 30 - Aug 31

A pool area with a rock formation backdrop, a wooden post, and a sign indicating a clinic.

A cozy log cabin interior with a fireplace, wooden furniture, and a television.

A wooden reception desk with a moose mural, a mounted cow head, and a framed map on the wall.

A hotel with a stone facade, a covered entrance, and a landscaped area with a small pond.

Stoney Creek Hotel St. Joseph

St. Joseph

$134

$155 total

includes taxes & fees

Aug 23 - Aug 24

A hotel room with a sofa, two beds, a patterned ottoman, a wall art piece, and a window with a view.

Home2 Suites By Hilton St. Joseph

St. Joseph

$102

$118 total

includes taxes & fees

Aug 30 - Aug 31

A swimming pool with a hot tub, a ladder, and a slide.

A reception area with a coffee station, a potted plant, and a banner promoting breakfast.

A hotel room with a large bed, two bedside tables with lamps, a desk, and a chair.

A reception area with a reception desk, a plant, a coffee station, and a sign for breakfast.

Quality Inn Cameron

Cameron

$111

$123 total

includes taxes & fees

Sep 20 - Sep 21

A hotel bathroom with a wooden bathtub, a desk with a lamp, a chair, a television, and a microwave.

A reception area with a marble counter, a fish tank, a welcome sign, and a 'Super 8' sign.

An indoor swimming pool with clear water, surrounded by white plastic chairs and tables, and a lifeguard sign on the wall.

A two-story building with a covered parking area and a brick facade.

Super 8 by Wyndham Cameron

Cameron

$84

$93 total

includes taxes & fees

Sep 4 - Sep 5

A hotel room with two beds, a desk, a television, and a bathroom visible through an open door.

A cozy room with a coffee machine, a clock, and a potted plant.

A 8 ft. clearance hotel entrance with a SureStay sign, brick exterior, and potted plants.

A hotel with a covered outdoor area, a brick building, and a sign for a nearby Subway.

SureStay Hotel by Best Western Cameron

Cameron

$78

$86 total

includes taxes & fees

Aug 26 - Aug 27

A hotel room with a bed, a desk, a chair, a kitchenette, and a framed picture on the wall.

A modern restaurant with a bar area, seating arrangements, and a kitchen in the background.

My Place Hotel St Joseph MO

St. Joseph

$89

$103 total

includes taxes & fees

Sep 6 - Sep 7

A hotel room with a large bed, a desk, a chair, and a TV on the wall.

A hotel room with a bed, a desk, a chair, a TV mounted on the wall, and an air conditioning unit.

Red Roof Inn Cameron

Cameron

$89

$98 total

includes taxes & fees

Sep 1 - Sep 2

A hotel room with a large bed, a red wall, and a cityscape painting above the bed.

A reception desk with a clock, decorative wall art, and American flags.

A hotel room with a television, a lamp, a microwave, and a desk with a chair.

AmeriStay Inn

St. Joseph

$72

$83 total

includes taxes & fees

Sep 13 - Sep 14

A large, historic brick building with a prominent tower and a grand entrance.

A brick building with a covered porch and a large bush of white flowers.

A traditional interior with a fireplace, wooden furniture, and a chandelier.

A grand room with a red patterned carpet, a large potted plant, a wooden staircase, and a chandelier.

Vineyard Mansion & Carriage House Bed & Breakfast

St. Joseph

$107

$157 total

includes taxes & fees

Aug 21 - Aug 22

A hotel room with two beds, a desk, a chair, and a television.

A hallway with a 7UP vending machine, white doors, and a brown mat.

A building with a 'welcome' sign, a number '6' on the door, and a covered entrance area.

A vending machine with snacks and a 7UP machine in a hallway with a staircase.

Motel 6 Saint Joseph, MO

St. Joseph

$70

$81 total

includes taxes & fees

Aug 23 - Aug 24

A living room with a dark sofa, two cushions, a small side table with a plant, and a floral wall decal with the text 'Stay a while'.

A room with a pool table, a projector displaying a Roku interface, and a basketball hoop.

A modern kitchen with black cabinets, a white stove, and a dining area with a wooden table and chairs.

Firefly Lofts

Cameron

$133

$331 total

includes taxes & fees

Aug 21 - Aug 22

A large brick building with multiple windows and a covered porch area.

A grand entrance with a stained glass window, a red upholstered sofa, and a wooden chair.

A covered porch with columns, potted plants, and a brick wall.

A red brick building with a garden in front.

Whiskey Mansion

St. Joseph

$156

$181 total

includes taxes & fees

Aug 21 - Aug 22

A gazebo with a metal roof and wooden benches.

A living room with a leather sofa, a glass coffee table, and various potted plants.

A hotel room with two beds, a nightstand with a lamp, a small table, a mirror, and a window.

A hotel room with a wooden desk, two red chairs, a TV mounted on the wall, a mirror, and a wardrobe.

Econo Lodge Cameron

Cameron

$75

$82 total

includes taxes & fees

Sep 6 - Sep 7

A reception desk with a "WELCOME" sign, a clock, and a mirror.

A kitchenette with a coffee machine, a trash bin, and a coffee sign on the wall.

A living room with a sofa, coffee table, and side tables.

A compact kitchenette with a microwave, sink, and small refrigerator.

Motel 6 Cameron, MO

Cameron

View all properties

Go beyond your typical stay in Clarksdale

Pet friendly

Pool

Family friendly

Check out reviews of Clarksdale hotels guests love

Stoney Creek Hotel St. Joseph

8/10 Good

"X"

My Place Hotel St Joseph MO

8/10 Good

"The stay was part enjoyable."

Whiskey Mansion

10/10 Excellent

"Olin is a great proprietor, and Holly and Sharon could not have been more helpful and kind in getting us going every morning with a hearty breakfast and wonderful cheer. I was with three kids and we all loved it. Will be back again."

SureStay Hotel by Best Western Cameron

10/10 Excellent

"It was an ok place to stay late at night. The staff was very pleasant "

Fairfield Inn & Suites by Marriott St. Joseph

10/10 Excellent

"We are always happy when we stay at Fairfield’s. Clean, good breakfast and staff is always friendly."

Quality Inn Cameron

10/10 Excellent

"Very welcoming staff. The breakfast was delicious and one of the staff showed us how to use the waffle machine without us asking. Very clean with ample parking. We’ll definitely stay there again."

Vineyard Mansion & Carriage House Bed & Breakfast

10/10 Excellent

"My daughter and I loved staying at the mansion. Beautiful property, excellent decor, and it was very clean. We stayed in Emma and we were very impressed with the room. The bed was incredibly comfortable as well as the couch. We felt like royalty. We have decided to make this a yearly girls trip destination. Thank you Jason for your hospitality."

Motel 6 Saint Joseph, MO

8/10 Good

"Yes. Air was nice and cool! No pets with me."

AmeriStay Inn

8/10 Good

"It’s an older property, worn linens and towels. However, the unit was clean and smelled GOOD (not your usual hotel musk), staff was helpful and kind."

Frequently asked questions

Can I book a refundable hotel in Clarksdale?

If you're looking for the flexibility to change your plans to Clarksdale, most accommodations offer refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Clarksdale be like during my visit?

The warmest months in Clarksdale are usually July and August with an average temp of 74°F. January and February are the chilliest months when the average temp is 33°F. The rainiest months are May and July.

Why should I book my Clarksdale hotel with Hotels.com?

There are plenty of reasons to book your Clarksdale travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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