Hotels in Santa Clara

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Check prices for these dates

Tonight
Feb 24 - Feb 25
Tomorrow
Feb 25 - Feb 26
This weekend
Feb 27 - Mar 1
Next weekend
Mar 6 - Mar 8

Where to stay in Santa Clara?

Poolside bar
Gamboa Rainforest Reserve
Gamboa Rainforest Reserve
3.5 star property
Colon
8.0 out of 10, Very Good, (705 reviews)
Immerse yourself in nature at this Colon retreat with guided wildlife tours showcasing monkeys and sloths. The 2 restaurants, marina, and pools complement stunning rainforest surroundings, while helpful staff ensure a memorable Gamboa adventure.
The price is $152
$167 total
includes taxes & fees
Feb 25 - Feb 26
Gamboa Rainforest Reserve
2 outdoor pools, pool umbrellas, sun loungers
Summit Rainforest & Golf Resort
Summit Rainforest & Golf Resort
4.0 star property
Panama City
8.4 out of 10, Very Good, (1,001 reviews)
Escape to paradise at this Panama City retreat with 2 outdoor pools, a golf course, and 3 restaurants. Near Summit Botanical Gardens & Zoo, you'll enjoy free breakfast and WiFi while the friendly staff cater to your needs.
The price is $94
$103 total
includes taxes & fees
Feb 26 - Feb 27
Summit Rainforest & Golf Resort
Restaurant
Mahogany Suites
Mahogany Suites
2.0 star property
Rousseau
9.2 out of 10, Wonderful, (5 reviews)
The price is $130
$143 total
includes taxes & fees
Feb 25 - Feb 26
Mahogany Suites
Interior detail
Albrook Inn
Albrook Inn
3.0 star property
Panama City
7.8 out of 10, Good, (582 reviews)
This Panama City hotel features lush gardens and a poolside bar just minutes from Albrook Shopping Mall and Cinta Costera. Guests praise the helpful staff while enjoying convenient amenities like free WiFi, parking, and an outdoor pool at this peaceful retreat.
The price is $65
$72 total
includes taxes & fees
Feb 25 - Feb 26
Albrook Inn
Outdoor pool, pool umbrellas, sun loungers
Holiday Inn Panama Canal by IHG
Holiday Inn Panama Canal by IHG
3.5 star property
Panama City
8.6 out of 10, Excellent, (456 reviews)
The price is $91
$100 total
includes taxes & fees
Mar 7 - Mar 8
Holiday Inn Panama Canal by IHG
Hallway
Modal
Modal
2.0 star property
Panama City
10.0 out of 10, Exceptional, (1 review)
The price is $61
$67 total
includes taxes & fees
Feb 25 - Feb 26
Modal
Lobby lounge
Renaissance Panama City Hotel
Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (158 reviews)
Soak in Panama City vibes at this luxury hotel with casino and poolside bar, just 4 minutes from Iglesia del Carmen Station. Enjoy free WiFi and valet parking while exploring nearby Albrook Shopping Mall and Avenida Balboa attractions.
The price is $135
$149 total
includes taxes & fees
Mar 2 - Mar 3
Renaissance Panama City Hotel
Outdoor pool, open 8:00 AM to 8:00 PM, pool umbrellas, sun loungers
Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals
Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals
3.5 star property
Calidonia
7.4 out of 10, Good, (200 reviews)
Steps from Avenida Balboa and Cinta Costera, this hotel offers an outdoor pool and El Baru restaurant serving international cuisine. With free breakfast, airport shuttle, and convenient access to Albrook Shopping Mall, you'll experience Panama's vibrant energy between sightseeing adventures.
The price is $66
$72 total
includes taxes & fees
Feb 25 - Feb 26
Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals
Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas
Marriott Panama Hotel
Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1,012 reviews)
Embrace the urban energy of Panama City at this sleek hotel right beside Albrook Shopping Mall. Jump into the outdoor pool, enjoy international cuisine at Canal Bistro, or sip drinks at one of 3 bars. With free WiFi and just minutes from Cinta Costera, shopping adventures await.
The price is $152
$167 total
includes taxes & fees
Mar 7 - Mar 8
Marriott Panama Hotel
Garden
Radisson Hotel Panama Canal
Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,007 reviews)
Panoramic views await at this Panama City hotel with 2 outdoor pools, a children's pool, and TGI Fridays restaurant. Just minutes from Albrook Shopping Mall and Amador Causeway, enjoy free WiFi and parking with airport shuttle service available.
The price is $85
$93 total
includes taxes & fees
Mar 24 - Mar 25
Radisson Hotel Panama Canal
Outdoor pool
Hyatt Regency Panama City
Hyatt Regency Panama City
4.5 star property
Bella Vista
9.8 out of 10, Exceptional, (202 reviews)
Immerse yourself in cosmopolitan Panama City. This upscale hotel boasts a full-service spa and free valet parking within walking distance of Avenida Balboa. Two bars and a restaurant await after workouts in the 24-hour fitness center.
The price is $174
$191 total
includes taxes & fees
Mar 14 - Mar 15
Hyatt Regency Panama City
3 outdoor pools, pool umbrellas, sun loungers
The Westin Playa Bonita Panama
The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very Good, (1,013 reviews)
The price is $228
$251 total
includes taxes & fees
Mar 27 - Mar 28
The Westin Playa Bonita Panama
50-inch LED TV with satellite channels
Arcadia Condo Suites
Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (220 reviews)
This Panama City aparthotel features spacious apartments with kitchens and washer/dryers for home-like comfort. Swim in the outdoor pool, grab a bite at the café, then relax on the rooftop terrace. Close to Avenida Balboa with free WiFi and parking.
The price is $84
$138 total
includes taxes & fees
Mar 1 - Mar 2
Arcadia Condo Suites
Terrace/patio
Hotel San Felipe
Hotel San Felipe
4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (306 reviews)
Unwind at this Panama City hotel with deep-tissue massages and aromatherapy at the full-service spa. A short walk to Cinta Costera, this spot offers a peaceful garden and welcoming bar. Praised for its helpful staff and prime location near Albrook Shopping Mall.
The price is $141
$155 total
includes taxes & fees
Mar 1 - Mar 2
Hotel San Felipe
Reception
MARINN Tropical Vibes Hotel
MARINN Tropical Vibes Hotel
3.5 star property
Amador
8.2 out of 10, Very Good, (229 reviews)
This Panama City hotel offers 6 restaurants and 3 bars near Fuerte Amador Resort & Marina. With free parking and WiFi, plus staff that earn rave reviews, you'll enjoy easy access to Albrook Shopping Mall while experiencing tropical comfort.
The price is $89
$98 total
includes taxes & fees
Feb 25 - Feb 26
MARINN Tropical Vibes Hotel
On the beach
The Beach House
The Beach House
3.0 star property
Amador
8.4 out of 10, Very Good, (416 reviews)
Immerse in coastal tranquility at this Panama City haven featuring an outdoor pool and refreshing pool bar. Within a short drive to Amador Causeway, Albrook Shopping Mall, and Cinta Costera, enjoy free WiFi and parking during your beach retreat.
The Beach House
Front of property
La Résidence Panamá
La Résidence Panamá
2.5 star property
Bella Vista
9.0 out of 10, Wonderful, (6 reviews)
Discover serene relaxation at this spa hotel, just minutes from Iglesia del Carmen Station. Enjoy pampering massages while staying within walking distance of Via Espana and Avenida Balboa. Albrook Shopping Mall and Cinta Costera are a quick 5-minute drive from this comfortable urban haven.
The price is $130
$143 total
includes taxes & fees
Feb 26 - Feb 27
La Résidence Panamá
Outdoor pool
Ramada Panama Centro Via Argentina
Ramada Panama Centro Via Argentina
3.0 star property
Bella Vista
7.4 out of 10, Good, (296 reviews)
Wake up to Panama City adventures from this downtown hotel with a rooftop terrace, outdoor pool, and bar. Just minutes from Iglesia del Carmen Station and near Albrook Shopping Mall and Avenida Balboa. Enjoy free WiFi and parking after workouts in the 24-hour gym.
The price is $68
$75 total
includes taxes & fees
Feb 25 - Feb 26
Ramada Panama Centro Via Argentina
Outdoor pool, open 8:00 AM to 8:00 PM, pool umbrellas, sun loungers
Best Western El Dorado Panama Hotel
Best Western El Dorado Panama Hotel
3.0 star property
Bethania
9.0 out of 10, Wonderful, (669 reviews)
The price is $90
$99 total
includes taxes & fees
Mar 17 - Mar 18
Best Western El Dorado Panama Hotel
Daily buffet breakfast (PAB 21 per person)
Sheraton Grand Panama
Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,011 reviews)
Immerse in luxury at this Panama City resort with outdoor pool and poolside bar. Located near Multiplaza Pacific Mall, indulge at the full-service spa or dine at 3 restaurants. Free WiFi, complimentary parking, and attentive staff enhance your stay.
The price is $134
$148 total
includes taxes & fees
Mar 8 - Mar 9
Sheraton Grand Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in Santa Clara

Culebra Cut

If you're planning a bit of sightseeing during your trip, head to Culebra Cut— just one of the landmarks located 5.8 mi (9.3 km) from central Santa Clara.
See properties

Learn more about Santa Clara

The region around Santa Clara is home to attractions such as Culebra Cut and Albrook Shopping Mall.

See all hotels in Santa Clara
Adobe

Check out reviews of Santa Clara hotels guests love

Principe Hotel and Suites

Principe Hotel and Suites

10/10 Excellent
"Always nice "
Kenneth 5-night trip
Posted 15 hours ago
Principe Hotel and Suites

Frequently asked questions

Can I book a refundable accommodation in Santa Clara?
If you want the flexibility to change your plans to Santa Clara, most properties offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Clara be like during my trip?
With an average temperature of 78°F, Santa Clara is a great place if you want to enjoy the sunshine year all year long.
Why should I book my Santa Clara accommodation with Hotels.com?
There are plenty of reasons to book your Santa Clara travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.