Hotels in Saint Leo

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An aerial view of a hotel with a heart-shaped pool surrounded by lounge chairs and umbrellas, with palm trees and a landscaped garden.

A hotel lobby with a reception desk, two sofas, a coffee table, and a large window.

A modern hotel room with a blue sofa, a desk, a bed, a large mirror, and a kitchen area.

A hotel room with two beds, a desk, a shower, and artwork on the walls.

OASIS BAY SUITES, Tampa, Busch Gardens, USF

Terrace Park

$96

$109 total

includes taxes & fees

Sep 21 - Sep 22

A hotel atrium with multiple floors, a central courtyard with palm trees, and a sign reading "Welcome to the Four Points by Sheraton Tampa Airport Westshore."

A lobby with a marble floor, two sofas, a coffee table, and a chandelier.

An indoor swimming pool with clear blue water, a tiled floor, and a few lounge chairs and tables along the edge.

A multi-story hotel with balconies, surrounded by palm trees and well-maintained landscaping.

Four Points by Sheraton Suites Tampa Airport Westshore

Westshore

$106

$120 total

includes taxes & fees

Sep 17 - Sep 18

A modern living room with a leather sofa, a coffee table, a bookshelf, and a large potted plant.

A hotel room with a large bed, a desk with a lamp, and a view of a cityscape at night.

A bar area with multiple high stools, a long counter, and a shelf with various bottles.

The Barrymore Hotel Tampa Riverwalk

Downtown Tampa

$143

$164 total

includes taxes & fees

Sep 14 - Sep 15

A patio with two chairs and a table, overlooking a pond with lily pads and a grassy area with trees.

An aerial view of a golf course with a pond, surrounded by buildings with blue roofs, and dense greenery.

A modern hotel room with a large window, a dining area, and a bathroom with a sink.

A poolside area with lounge chairs, a person sitting on the edge of the pool, and a building in the background.

Saddlebrook Resort

Wesley Chapel South

$141

$189 total

includes taxes & fees

Sep 20 - Sep 21

A kitchenette with a black countertop and wooden cabinets, a water dispenser, and a framed map on the wall.

A reception area with a counter, a wooden bench, and a seating area with chairs.

A hotel room with two beds, a desk, a chair, a bookshelf, and a kitchen area.

A compact kitchen with wooden cabinetry, a microwave, a stainless steel sink, and a refrigerator.

HomeTowne Studios by Red Roof Tampa - Airport

Town 'n' Country

$76

$86 total

includes taxes & fees

Sep 14 - Sep 15

A swimming pool with clear water, surrounded by lounge chairs and umbrellas, and a glass ceiling above.

A hotel dining area with a wooden table, chairs, a menu board, and a coffee machine.

A hotel lobby with a reception desk, a lobby shop, and a seating area with chairs and a potted plant.

Marriott Tampa Westshore

Westshore

$161

$182 total

includes taxes & fees

Sep 25 - Sep 26

A reception area with a wooden reception desk, a welcome sign, a counter with a cash register, and a door to the right.

A kitchen area with a chalkboard menu, waffle station, and various kitchen appliances.

A Hampton Inn hotel with a clear entrance, a sign above the entrance, and a handicap accessibility sign.

A hotel room with two beds, a desk, a TV, and a window with blinds.

Hampton Inn Dade City - Zephyrhills

Dade City

$98

$109 total

includes taxes & fees

Sep 20 - Sep 21

A hotel room with a bed, a desk, a TV, a wardrobe, and a bathroom.

A swimming pool with a metal ladder, lounge chairs, and a white fence.

Spot X Hotel Wesley Chapel - Tampa Area

Wesley Chapel

$84

$94 total

includes taxes & fees

Sep 9 - Sep 10

A modern hotel lobby with large windows, a blue sofa, a round coffee table, and a seating area with a small rug.

A modern indoor pool area with a tiled edge, a table with chairs, and a seating area with lounge chairs.

A balcony with a table and chairs, overlooking a cityscape with tall buildings.

Mint House Tampa Downtown by Kasa

Downtown Tampa

$125

$142 total

includes taxes & fees

Sep 28 - Sep 29

Hotel Haya

Ybor City

$135

$188 total

includes taxes & fees

Sep 9 - Sep 10

A hotel entrance with palm trees, a fountain, and outdoor seating.

A modern coffee shop interior with a wooden counter, seating area, and various coffee-related products on display.

A waterfront hotel with a convention center, marina, and city skyline in the background.

A spacious lobby with multiple seating areas, a central plant arrangement, and a staircase leading to an upper level.

Embassy Suites by Hilton Tampa Downtown Convention Center

Downtown Tampa

$163

$225 total

includes taxes & fees

Sep 14 - Sep 15

A hotel with multiple floors, a swimming pool area, and a dome structure.

A pool bar and grill with outdoor seating and a modern architectural design.

A modern spa and salon interior with a central reception desk, seating area, and large windows.

A spacious lobby with a grand piano, a large chandelier, and a quote by Elvis Presley on the wall.

Seminole Hard Rock Hotel & Casino Tampa

Tampa

$219

$277 total

includes taxes & fees

Sep 14 - Sep 15

A hotel room with a large bed, a sofa, a coffee table, a desk, and a window with curtains.

A spacious lobby with a beige sofa, two armchairs, a coffee table, and a large potted plant.

A reception desk at the Roadstar Hotel with a clock, a digital screen, and a sign indicating breakfast availability.

A swimming pool with lounge chairs and palm trees.

Roadstar Hotel Zephyrhills

Zephyrhills

$77

$91 total

includes taxes & fees

Sep 9 - Sep 10

A hotel room with a large bed, a desk with a computer, a TV, and a window with curtains.

A self-service snack and beverage area with refrigerated drink dispensers and shelves stocked with various snacks and packaged goods.

A hotel with a prominent sign, a central tower, and a well-lit facade.

A hotel reception area with marble counters, a cityscape mural, and a large pillar.

La Quinta Inn & Suites by Wyndham Tampa Brandon Regency Park

Limona Improvement

$92

$104 total

includes taxes & fees

Sep 15 - Sep 16

A covered outdoor seating area with a wooden deck, surrounded by greenery and palm trees.

A covered outdoor area with a pool, wooden deck, and palm trees.

A modern hotel room with a grey sofa, a round coffee table, a large artwork on the wall, a dark headboard, and a bedside table with a lamp.

A modern bedroom with a large bed, a television, a chandelier, and a wall-mounted abstract painting.

Hilton Tampa Airport Westshore

Westshore

$106

$120 total

includes taxes & fees

Sep 10 - Sep 11

A reception area with two counters, framed pictures on the wall, and pendant lighting.

A clean, well-organized store with a refrigerated section, snack shelves, and a wooden counter.

A modern restaurant with booths, tables, and a kitchen area.

Drury Plaza Hotel Tampa Brandon

Tampa

$113

$128 total

includes taxes & fees

Sep 13 - Sep 14

A modern hotel lobby with seating areas, a central coffee station, and a large painting on the wall.

A nighttime pool area with lounge chairs and a pool.

A modern hotel lobby with a central seating area, a kitchen area, and a dining space.

La Quinta Inn by Wyndham Tampa Near Busch Gardens

Terrace Park

$76

$86 total

includes taxes & fees

Sep 10 - Sep 11

A poolside area with lounge chairs, a fire pit, and outdoor seating.

A modern reception area with a wooden reception desk, multiple seating arrangements, and hanging pendant lights.

An outdoor seating area with fire pits, umbrellas, and modern furniture.

A bar area with a long counter, multiple bar stools, and a seating area with white chairs.

Hyatt House Tampa Airport Westshore

Westshore

$143

$162 total

includes taxes & fees

Sep 17 - Sep 18

A rooftop swimming pool with a city skyline in the background, palm trees, and a 'No Diving' sign.

A modern living room with a built-in entertainment system, wooden cabinetry, and a flat-screen TV.

A hotel room with a large window, a bed, a desk, and a chair.

A reception area with a "WELCOME TO CIGAR CITY" sign, a reception desk, and multiple elevators.

Hampton Inn Tampa Downtown Channel District

Downtown Tampa

$135

$155 total

includes taxes & fees

Sep 14 - Sep 15

A Best Western hotel with a prominent sign, multiple floors, and a well-lit entrance.

A conference room with a long table, six chairs, three pendant lights, two framed artworks, and a flat-screen TV on the wall.

A modern reception area with a teal-tiled backsplash, a wooden counter, and a green office chair.

A hotel room with a large bed, a desk, a chair, and a nightstand with lamps.

Best Western Wesley Chapel

Wesley Chapel

$95

$106 total

includes taxes & fees

Sep 14 - Sep 15

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Go beyond your typical stay in Saint Leo

Pet friendly

Pool

Family friendly

Cottage

Learn more about Saint Leo

The region around Saint Leo is home to attractions such as Mirada Lagoon and Dade City Atlantic Coast Line Railroad Depot.

See all hotels in Saint Leo

A building with a corner featuring arched windows and a triangular pediment against a clear blue sky.

Check out reviews of Saint Leo hotels guests love

Spot X Hotel Wesley Chapel - Tampa Area

10/10 Excellent

"Premises were nice. Staff were fantastic. Glad to enjoy a hot breakfast in the mornings along w/ the basics."

Hyatt Place Tampa/Wesley Chapel

10/10 Excellent

"There was some signs of wear but the hotel is exceptionally clean. Staff very helpful"

Saddlebrook Resort

10/10 Excellent

"Our stay was wonderful. We’re in Florida and extended our trip for the drive through safari. When we arrived at Saddlebrook we felt right at home. The staff was absolutely amazing. I met some awesome guests, as well. We did leave the following day though nothing at fault to the resort however, it truly is only to relax. There’s not much to do other than swim. I wish the best for this place. Any negative review is coming from someone who doesn’t know how to be polite to others or wanted to be pampered like the Ritz. When I called, they came. They were overly pleasant & helpful and most importantly, my kids were super safe there. If you want somewhere the adults can relax and let the kids play while you lay on a beach chair and no one is around you, this is your place! Your kids need to be able to pkay by themselves though."

Roadstar Hotel Zephyrhills

10/10 Excellent

"Room was renovated and everything was fine."

Hampton Inn & Suites Tampa-Wesley Chapel

10/10 Excellent

"Clean room, friendly staff, and nice amenities."

SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms

8/10 Good

"The front desk person who did the check-in was great! I saw him solve 3 issues with knowledge, a great attitude, and timely efficiency. He was very friendly and polite to every guest. Excellent customer service!"

Quality Inn Zephyrhills-dade City

10/10 Excellent

"100% recommend."

Days Inn by Wyndham Brooksville/Dade City

10/10 Excellent

"Clean rooms and friendly staff"

Holiday Inn Express & Suites Tampa North - Wesley Chapel by IHG

10/10 Excellent

"clean, awesome showers and great area"

Frequently asked questions

What hotels do travelers like in Saint Leo?

Guests like Saddlebrook Resort, Roadstar Hotel Zephyrhills and Quality Inn Zephyrhills-dade City.

Can I book refundable hotels in Saint Leo?

If you're looking for the flexibility to change your plans to Saint Leo, most hotels provide refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Saint Leo be like during my trip?

August and July are typically the warmest months in Saint Leo when the average temp is 81°F. January and February are the coldest months when the average temperature is 63°F. August and July are the months with the most rain.

Why should I book my Saint Leo hotel with Hotels.com?

There are lots of reasons to book your Saint Leo trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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