Hotels in New Madrid

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Feb 26 - Feb 27
Tomorrow
Feb 27 - Feb 28
This weekend
Feb 27 - Mar 1
Next weekend
Mar 6 - Mar 8

Where to stay in New Madrid?

Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi
Super 8 By Wyndham Marston
Super 8 By Wyndham Marston
2.0 star property
Marston
8.2 out of 10, Very Good, (50 reviews)
Discover comfort at this Marston hotel, just off Interstate 55. Wake up to a complimentary full breakfast before exploring nearby attractions. Free WiFi and parking add value to your stay in this convenient Missouri location.
The price is $67
$76 total
includes taxes & fees
Feb 28 - Mar 1
Super 8 By Wyndham Marston
Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets
New Orleans Inn Portageville
New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (746 reviews)
Escape to this welcoming Portageville inn where attentive staff are available around the clock. Enjoy clean, comfortable rooms, complimentary WiFi, and free parking throughout your stay. A convenient base for exploring the region, just under an hour from Cape Girardeau.
The price is $63
$68 total
includes taxes & fees
Mar 1 - Mar 2
New Orleans Inn Portageville
Free daily continental breakfast
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (447 reviews)
Experience Sikeston from this hotel with free breakfast, WiFi, and parking. Take a morning dip in the indoor pool or hit the fitness center. Near Central Park and Sikeston Depot Museum, guests love the helpful staff and clean rooms.
The price is $87
$99 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Express & Suites Sikeston Southwest by IHG
Property amenity
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (60 reviews)
Located in Sikeston, this hotel offers free breakfast, WiFi, and parking. Take a refreshing swim in the indoor pool or grab a bite at the restaurant. Nearby attractions include Central Park and Sikeston Depot Museum for local exploration.
The price is $101
$114 total
includes taxes & fees
Mar 5 - Mar 6
Fairfield Inn & Suites by Marriott Sikeston
Exterior
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (485 reviews)
Dive into vacation mode at this welcoming hotel with an indoor pool and fitness center near Central Park. After enjoying the complimentary breakfast, explore Sikeston Depot Museum before returning to relax in modern rooms with free WiFi.
The price is $100
$113 total
includes taxes & fees
Mar 8 - Mar 9
Hampton Inn Sikeston
Property amenity
TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (12 reviews)
The price is $114
$129 total
includes taxes & fees
Mar 8 - Mar 9
TownePlace Suites by Marriott Sikeston
Soundproofing, free WiFi, bed sheets
Travel Inn
Travel Inn
2.5 star property
Marston
6.0 out of 10, (118 reviews)
The price is $50
$57 total
includes taxes & fees
Mar 14 - Mar 15
Travel Inn
Standard Room, 2 Double Beds, Non Smoking | Blackout drapes, iron/ironing board, free WiFi, bed sheets
Reelfoot Lake Inn
Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (467 reviews)
The price is $70
$80 total
includes taxes & fees
Mar 19 - Mar 20
Reelfoot Lake Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top landmarks in New Madrid

New Madrid Historical Museum

4.1/5 (17 reviews)
Experience the powerful 1811-1812 earthquakes through artifacts and interactive displays at this riverside museum. Don't miss the fascinating Civil War exhibits and the curator's stories about local history.
See properties

River Ridge Winery

3.9/5 (10 reviews)
Sip handcrafted wines in a century-old farmhouse overlooking the Mississippi River hills. The complimentary tastings showcase everything from dry to sweet varieties, perfect for enjoying on their scenic grounds.
See properties

Learn more about New Madrid

New Madrid is applauded for its cultural attractions such as New Madrid Historical Museum and Hunter-Dawson State Historic Site.

See all hotels in New Madrid
Mississippi River Walk at New Madrid. A magnificent view of the Mississippi river from atop of the levee. A steamboat is docked down river. .

Check out reviews of New Madrid hotels guests love

Frequently asked questions

What hotels do travelers like in New Madrid?
Guests like Super 8 By Wyndham Marston and Travel Inn.
Can I book refundable accommodations in New Madrid?
If you need the flexibility to change your travel plans to New Madrid, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in New Madrid be like during my vacation?
The warmest months in New Madrid are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 42°F. The rainiest months are March and April.
Why should I book my New Madrid hotel through Hotels.com?
There are plenty of reasons to book your New Madrid travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.