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Hotels in Melrose

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Where to stay in Melrose?

A swimming pool with a metal ladder, surrounded by a white fence and green chairs.

A living room with a curved sofa, a wooden cabinet, and a fish tank.

A refrigerated display case with beverages and snacks, and a shelf with bottled water and other beverages.

A hotel room with a patterned carpet, a sofa, a small table, a lamp, and a door with a notice.

Best Western Waldo Inn and Suites

Waldo

$103

$115 total

includes taxes & fees

Sep 7 - Sep 8

A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.

A Holiday Inn Express building with a modern design, featuring multiple windows and a flat roof.

An outdoor patio with tables and chairs, a stone wall, and a view of a street with trees and buildings.

A modern reception desk area with a blue geometric wall design, wooden accents, and a visible reception counter.

Holiday Inn Express Starke by IHG

Starke

$110

$122 total

includes taxes & fees

Sep 9 - Sep 10

A covered corridor with a row of parked cars on one side and a building with blue trim on the other.

A hotel room with a bed, a TV mounted on the wall, a remote control on a table, and a door leading to another room.

A bathroom with a toilet, sink, and mirror.

Soho Inn Waldo

Waldo

$54

$61 total

includes taxes & fees

Sep 7 - Sep 8

A kitchen with a sink, a microwave, and cabinets.

A small building with a yellow door, surrounded by trees and parked cars.

A compact kitchen with a green countertop, a patterned sofa, and a wall-mounted light fixture.

A room with a patterned sofa, a green door with a decorative glass panel, and a framed picture on the wall.

The Humming Bird Suite - Affordable Lakefront Fun

Keystone Heights

$80

$123 total

includes taxes & fees

Sep 7 - Sep 8

A clear blue swimming pool with a metal safety fence, surrounded by a building with multiple windows and balconies.

A single-story motel with a red roof and beige walls. It features a covered front porch and a small parking area.

A hotel room with two beds, each with a patterned bedspread. There are two wall-mounted lamps on the nightstand between the beds.

A hotel room with two beds, a bedside table with a lamp, and a painting on the wall.

Red Carpet Inn

Starke

$59

$65 total

includes taxes & fees

Sep 8 - Sep 9

A hotel room with a bed, bedside lamps, a nightstand, a mirror, a bathroom with a sink and a bathtub.

A rectangular pool with a depth of 3 feet 2 inches, surrounded by a white fence and a building with a red roof in the background.

A hotel room with a large bathtub, a bed with a patterned bedspread, two bedside lamps, a nightstand, a dresser, a mirror, and a television.

A bathroom with a bathtub, a sink, and a mirror.

Americas Best Value Inn Starke

Starke

$75

$83 total

includes taxes & fees

Sep 7 - Sep 8

A modern kitchen with dark cabinets, stainless steel appliances, and a wooden ceiling.

A porch with two Adirondack chairs, a wooden door, and a sign reading "Downtown Studio Depot Village".

A bathroom with a white vanity, a round mirror, and a black faucet.

A modern building with a unique facade featuring a grid of colorful panels.

Depot Village

Gainesville

$59

$134 total

includes taxes & fees

Sep 7 - Sep 8

A hotel lobby with a seating area, a sofa, a table, and a lamp.

A snack and treat display area with refrigerated sections and shelves stocked with various snacks.

A hotel lobby with a reception desk, seating area, and a large wall advertisement.

A hotel lobby with multiple seating areas, including tables and booths, a coffee station, and a reception desk.

Hampton Inn & Suites Gainesville-Downtown

Downtown Gainesville

$92

$103 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a large bed, a nightstand, a chair, a window with a view of greenery, and a beach-themed wall mural.

A modern bathroom with a large mirror, a sink, and a hairdryer.

A reception area with a Days Inn sign, a reception desk, a blue couch, and a plant.

Days Inn by Wyndham Gainesville Hospital/University Area

Gainesville

$65

$73 total

includes taxes & fees

Sep 7 - Sep 8

A modern living room with a fireplace, comfortable seating, a flat-screen TV, and a large window.

A hotel room with a bed, a desk, a chair, a sofa, and a window.

A modern hotel lobby with a reception desk, seating area with chairs and ottomans, a large artwork, and a corridor leading to other rooms.

A modern hotel lobby with a long dining table, multiple seating areas, and a large window with curtains.

Comfort Suites Gainesville near University

Gainesville

$85

$95 total

includes taxes & fees

Oct 4 - Oct 5

A gazebo with a tiled roof, surrounded by stone pillars and palm trees.

A modern hotel room with a large bed, bedside tables, a desk, and a mirror.

A conference room with two desks, two chairs, and two monitors.

A reception area with a modern design, featuring a reception desk, a blue patterned wall, and a glass door leading outside.

Best Western Starke

Starke

$97

$108 total

includes taxes & fees

Sep 7 - Sep 8

A modern interior with a staircase, a seating area, and a colorful abstract wall design.

A modern hotel lobby with a round table featuring two drinks, a sofa, and a colorful wall art piece.

A spacious lobby with modern furniture, large windows, and a colorful abstract wall.

A rooftop pool area with lounge chairs, a small table, and a fire pit.

Hyatt Place Gainesville Downtown

Downtown Gainesville

$98

$110 total

includes taxes & fees

Sep 20 - Sep 21

A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.

A hotel room with a large window offering a view of a cityscape, a blue armchair, and a small table with a lamp.

A hotel lobby with a stone wall, a flat-screen TV, orange upholstered seating, and a lamp.

A hotel room with two beds, a large headboard, bedside lamps, and a view of the outdoors through sheer curtains.

Drury Inn & Suites Gainesville

Gainesville

$105

$118 total

includes taxes & fees

Sep 13 - Sep 14

A hotel lobby with a wooden floor, a chandelier, a ceiling fan, a reception desk, and a wall-mounted information board.

A hotel room with a flat-screen TV, a refrigerator, a microwave, and a wooden dresser.

A bathroom with a granite countertop, a white sink, a mirror, a towel rack, a wooden hanger, and a towel hanging on the rack.

A spacious hallway with wooden flooring, a chandelier, and large windows offering views of the outside.

Gator Town Inn

Gainesville

$65

$73 total

includes taxes & fees

Sep 7 - Sep 8

A dining area with a round table, chairs, a chandelier, and a spiral staircase with a view to the outside.

A kitchen with white cabinets, a coffee machine, and a microwave.

A bathroom with a white sink, a mirror, and a shower area.

A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.

University Inn Gainesville

Gainesville

$58

$65 total

includes taxes & fees

Sep 7 - Sep 8

A wooden dock with a chair, surrounded by trees and a calm water body.

A small, single-story building with a blue exterior, a wooden door, and a window.

A living room with a leather sofa, a TV on a wooden stand, a lamp, a bookshelf, and a painting on the wall.

A wooden cabin rental area with a guest registration desk, a sign for cabin rentals, and a sign indicating happy hour hours.

Yearling Restaurant and Cabins

Hawthorne

$139

$156 total

includes taxes & fees

Sep 7 - Sep 8

A hotel room with two beds, a ceiling fan, a TV, and a desk with a chair.

A hotel with a modern facade, a covered entrance, and a palm tree in front.

A modern building with a gray facade, a large window, and a landscaped area with a crocodile sculpture.

HOM Hotel Gainesville, SureStay Collection by Best Western

Gainesville

$77

$87 total

includes taxes & fees

Sep 13 - Sep 14

A swimming pool with a white fence, palm trees, and a building with balconies in the background.

A hotel reception area with a modern design, featuring a reception desk, a coffee station, and a view of the outdoors.

A small indoor seating area with a vending machine stocked with snacks and drinks, and a glass door entrance.

A hotel corridor with a covered balcony, palm trees, and a lawn.

Motel 6 Starke, FL

Starke

$63

$70 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a bed, two bedside tables with lamps, a large bathtub, and green walls.

A breakfast bar with a juice dispenser, cereal boxes, and fruit bowls.

A Sleep Inn & Suites building with a clear entrance, a covered waiting area, and a parking lot.

Outdoor lounge chairs with metal frames and fabric seats, arranged in rows.

Sleep Inn & Suites University/Shands

Gainesville

$76

$91 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with a bed, a sofa, a desk, and a chair.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A clean, well-organized snack and beverage area with two beverage dispensers, shelves stocked with snacks, and a white countertop.

A hotel reception area with a reception desk, a counter, and a seating area with tables and chairs.

Holiday Inn Express Palatka Northwest by IHG

Palatka

$126

$140 total

includes taxes & fees

Sep 13 - Sep 14

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Go beyond your typical stay in Melrose

Pet friendly

Pool

Apartment

Hot tub

Cottage

Family friendly

Learn more about Melrose

The region around Melrose is home to attractions such as Santa Fe Lake and Gainesville Raceway.

See all hotels in Melrose

A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.

Check out reviews of Melrose hotels guests love

DoubleTree by Hilton Gainesville

8/10 Good

"Solid hotel, and great sized rooms. Rooms and hotel are a little dated, but super clean and the bed was good. The A/C unit was a little on the noisy side, but we'd certainly stay again."

Hilton University of Florida Conference Center Gainesville

10/10 Excellent

"Overall, a great stay."

Comfort Suites Gainesville near University

10/10 Excellent

"Located close to UF, clean and a professional staff"

Drury Inn & Suites Gainesville

10/10 Excellent

"Our family loved the free drinks and food in the evening. The breakfast was also really good- great hot options. Hotel and room was clean and comfortable."

Comfort Inn Gainesville - University Area

10/10 Excellent

"Staff was extremely friendly and helpful even had a tailgate party for the gators game close to everything"

Frequently asked questions

Can I book a refundable hotel in Melrose?

If you're looking for the flexibility to change your travel plans to Melrose, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Melrose if I want a vacation home instead of a traditional hotel?

If you want to find a good alternative to a hotel, browse our selection of 24 vacation homes. You can also book one of the 6 cabins for your stay.

What will the weather in Melrose be like during my trip?

July and August are typically the warmest months in Melrose when the average temp is 80°F. January and February are the coldest months when the average temperature is 60°F. August and July are the months with the most rain.

Why should I book my Melrose accommodation with Hotels.com?

There are lots of reasons to book your Melrose trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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